Autocrine positive regulatory feedback of glucocorticoid secretion: Glucocorticoid receptor directly impacts H295R human adrenocortical cell function

Molecular and Cellular Endocrinology

Volumn 395, Issue 1-2, 2014, Pages 1-9

  Asser, Laetitia ^a,b   Hescot, Ségolène ^a,b   Viengchareun, Say ^a,b   Delemer, Brigitte ^c   Trabado, Séverine ^a,b,d   Lombès, Marc ^a,b,d  

^a INSERM   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c Service d'Endocrinologie Centre Hospitalier de Reims   (France)

^d BICÊTRE HOSPITAL   (France)

Author keywords

Adrenocortical cell; Glucocorticoid biosynthesis; Glucocorticoid receptor

Indexed keywords

ALDOSTERONE SYNTHASE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CORTICOTROPIN; CORTODOXONE; CYTOCHROME P450; CYTOCHROME P450 11B1; DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; HYDROCORTISONE; HYDROXYPROGESTERONE; MESSENGER RNA; MIFEPRISTONE; SMALL INTERFERING RNA; STEROID 21 MONOOXYGENASE; STEROIDOGENIC FACTOR 1; UNCLASSIFIED DRUG; HORMONE ANTAGONIST;

ADRENAL CORTEX; ADRENAL CORTEX CELL; ARTICLE; AUTOCRINE EFFECT; CELL FUNCTION; CELL PROLIFERATION; CELL VIABILITY; DRUG MECHANISM; HUMAN; HUMAN CELL; HYDROCORTISONE RELEASE; POSITIVE FEEDBACK; PRIORITY JOURNAL; STEROID RELEASE; STEROIDOGENESIS; SUPERNATANT; AGONISTS; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS); TUMOR CELL LINE;

17-ALPHA-HYDROXYPROGESTERONE; ADRENAL CORTEX; AUTOCRINE COMMUNICATION; CELL LINE, TUMOR; CORTODOXONE; DEXAMETHASONE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GLUCOCORTICOIDS; HORMONE ANTAGONISTS; HUMANS; HYDROCORTISONE; MIFEPRISTONE; RECEPTORS, GLUCOCORTICOID;

EID: 84905859396     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2014.07.012     Document Type: Article

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