Frequency distribution of Hepatitis C Virus (HCV) genotypes and its association with viral loads in chronic HCV infected patients of Isfahan, Iran

Journal of Pure and Applied Microbiology

Volumn 8, Issue SPEC. ISS. 1, 2014, Pages 293-298

  Shanehsazzadeh, Mehrnaz ^a   Rad, Javad Sharifi ^b   Pourazar, Abasalli ^a   Behbahani, Mandana ^c  

^a Department of Medicinal Biology Zist Partak Institute Academic Center for Education and Research   (Iran)

^b ZABOL UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c UNIVERSITY OF ISFAHAN   (Iran)

Author keywords

Genotyping; HCV; Real time PCR; Viral load

Indexed keywords

EID: 84905858187     PISSN: 09737510     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Berry, V., Arora, R.and Paul P. Hepatitis C-Clinical outcome and diagnosis. JK. Sci., 2005; 7: 129-32.
2. Seeff, L.B., Hollinger, F.B., Alter, H.J., Wright, E.C., Cain, C.M., Buskell, Z.J.et al, . Long-term mortality and morbidity of transfusion- associated non-A, non-B, and type C hepatitis; a National Heart, Lung, and Blood Institute collaborative study. Hepa. J., 2001; 33: 455-63 (Pubitemid 32119036)
3. Alavian, S.M., Adibi, P. and Zali, M.R. Hepatitis C virus in Iran.Epidemiology of an emerging infection. Arch Iranian Med., 2005; 8: 84-90. (Pubitemid 40613753)
4. Simmonds, P. Genetic diversity and evolution of hepatitis C virus-15 years on. J GenerViro., 2004; 85: 3173-88. (Pubitemid 39445434)
5. Zein, N.N. and Persing, D.H. Hepatitis C genotypes: current trends and future implications. Mayo Clin Proc., 1996; 71: 458-62 (Pubitemid 26144150)
6. Jimenez-Mendez, R., Uribe-Salas, F.,López-Guillen, P.,Cisneros-Garza, L. and Castañeda-Hernandez, G. Distribution of HCV genotypes and HCV RNA viral load in different regions of Mexico. AnnalsHepa., 2010; 9: 33-9
7. Abid, K., Quadri, R., Veuthey, A.L., Hadengue, A. and Negro, F. A novel hepatitis C virus (HCV) subtype from Somalia and its classification into HCV clade 3. J Gen & Viro., 2000; 81: 1485-93. (Pubitemid 30342896)
8. Trepo, C. Genotype and viral load as prognostic indicators in the treatment of hepatitis C. J Viral Hepa., 2000; 7:250-7.
9. Bell H., Hellum K., Harthug S., Maeland A., Ritland S., Myrvang B., Lippe B V D., Rakenerud N., Skaug K., Gutigard B-G., Skjaerven R., Prescott L E., Simmonds P., Group C. Genotype, viral load and age as independent predictors of treatment outcome of interferon-± 2a treatment in patients with chronic hepatitis C. Sc and J Infect Dis. 1997; 29: 17-22
10. Yoshioka, K., Kakumu, S., Wakita, T.Ishikawa, T., Itoh, Y.,Takayanagi, M., et al. Detection of hepatitis C virus by polymerase chain reaction and response to interferon-alpha therapy: relationship to genotypes of hepatitis C virus. Hepa., 1992; 16: 293-9.
11. Dalgard, O., Bjoro, K., Hellum, K.B.,Myrvang, B., Ritland, S., Skaug, K., et al.Treatment with pegylated interferon and ribavarin in HCV infection with genotype 2 or 3 for 14 weeks:a pilot study. Hepa., 2004; 40:1260-5. (Pubitemid 39656999)
12. Wagner, M.V., Huber, M., Berg, T., Hinrichsen, H., Rasenack, J., Heintges, T., et al. Peginterferon-alpha-2a (40KD) and ribavirin for 16 or 24 weeks in patients with genotype 2 or 3 chronic hepatitis C. Gastroentero., 2005; 129: 522-7. (Pubitemid 41096640)
13. Shakil, A.O., Conry-Cantilena, C., Alter, H.J.,Hayashi, P., Kleiner, D.E., Tedeschi, V., et al. Volunteer blood donors with antibody to hepatitis C virus:clinical, biochemical, virologic, and histologic features. The Hepatitis C Study Group. Ann Int Med., 1995; 123: 330-7
14. Ahmad, W., Ijaz, B., Javed, T.F., Jahan, S., Shahid, I.,Khan, F.M., et al. HCV genotype distribution and possible transmission risks in Lahore, Pakistan. Wor J Gastroentero., 2010; 16: 4321-8.
15. Moucari R, Ripault MP, Martinot-Peignoux M, Voitot H, Cardoso A-C, Stern C, Boyer N, Maylin S, Nicolas-Chanoine M-H, Vidaud M, Valla D, Bedrossa P, Marcellin P. Insulin resistance and geographical origin: major predictors of liver fibrosis and response to peginterferon and ribavarin in HCV-4. Gut. 2009; 58: 1662-1669.
16. Shaker, O., Ahmed, A., Doss, W. and Abdel-Hamid, M. MxA expression as marker for assessing the therapeutic response in HCV genotype 4 Egyptian patients. J Viral Hepati., 2010; 17: 794-9.
17. Ohno, O., Mezokami, M., Wu, R., Saleh, MG., Ohba, K., Orito, E., et al. New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a. J Clin Microbiol., 1997; 35: 201-202.
18. Idrees, M., Riazuddin, S. Frequency distribution of hepatitis C virus genotypes in different geographical regions of Pakistan and their possible routes of transmission. BMC Infect Dis., 2008; 23(8) :69.
19. Muhammad, N. and Jan, M.A.Frequency of hepatitis "C" in Buner, NWFP.J College Physi& Surge Pakistan., 2005; 15: 11-4.
20. Ali, A., Ahmed, H. and Idrees, M. Molecular epidemiology of Hepatitis C virus genotypes in Khyber Pakhtoonkhaw of Pakistan.Viro J., 2010; 203:1-7.
21. Sajid, A., Ayaz, A., Raham Sh. Kh., Sanaullah, Kh., Muhammad, H., Sumera, A. Kh., Amjad, I., Abid, A.Kh., Abdul, W., Taj, Ur R., and Ali, H. B. Genotyping of HCV RNA Reveals That 3a Is the Most Prevalent Genotype in Mardan, Pakistan. Advances in Virology ., 2014;Article ID 606201, 5 pages
22. Altuglu, I., Soyler, I., Ozacar, T. and Erensoy, S. Distribution of hepatitis C virus genotypes in patients with chronic hepatitis C infection in Western Turkey. Intional J Infection Dis., 2008; 12: 239-44. (Pubitemid 351539094)
23. Chowdhury, A., Santra, A., Chaudhuri, S., Dhali, G.K., Chaudhuri, S., Maity, S.G., et al.Hepatitis C virus infection in the general population:a community-based study in West Bengal, India. Hepa., 2003; 37: 802-9. (Pubitemid 36397391)
24. Tokita, H.,Okamoto, H., Luengrojanakul, P., Vareesangthip, K., Chainuvati, T., Iizuka, H.,et al.Hepatitis C virus variants from Thailand classifiable into five novel genotypes in the sixth (6b), seventh (7c, 7d) and ninth (9b, 9c) major genetic groups. J Gen &Viro., 1998; 76: 2329-35.
25. Zarkesh-Esfahani, H., T Kardi, M., Edalati, MHepatitisCvirus genotype frequency in Isfahan province of Iran: a descriptive cross-sectional study. Virology Journal ., 2010; 7: 69
26. Pawlotsky, J.M. Mechanism of antiviral treatment efficacy and failure in chronic hepatitis C. Antivir Res., 2003; 59: 1-11.
27. Roman, F., Hawotte, K., Struck, D., et al. Hepatitis C virus genotypes distribution and transmission risk factors in Luxembourg from 1991 to 2006. World J Gastroenterol., 2008; 14: 1237-43. (Pubitemid 351356332)
28. Ziyaeyan, M., Alborzi,A., Jamalidoust, M., Badiee, P., Moeini,M., Kadivar, A. Prevalence of hepatitis C virus genotypes in chronic infected patients, southern Iran. Jundishapur Journal of Microbiology., 20114; 3: 141-146.