Homocysteine induces the expression of C-reactive protein via NMDAr-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells

Atherosclerosis

Volumn 236, Issue 1, 2014, Pages

  Pang, Xiaoming ^a   Liu, Juntian ^a   Zhao, Jingjing ^a   Mao, Junjun ^b   Zhang, Xiaolu ^a   Feng, Liuxin ^a   Han, Chunjie ^c   Li, Ming ^a   Wang, Shuyue ^a   Wu, Di ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b XI'AN MEDICAL UNIVERSITY   (China)

^c Shaanxi Institute for Food and Drug Control   (China)

Author keywords

Atherosclerosis; C reactive protein; Homocysteine; Inflammation; Vascular smooth muscle cells

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; C REACTIVE PROTEIN; DIZOCILPINE; HOMOCYSTEINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA ANTIBODY; INTERLEUKIN 6 ANTIBODY; LUCIGENIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUTRALIZING ANTIBODY; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; THENOYLTRIFLUOROACETONE; CATION; DIPHENYLIODONIUM SALT; DIZOCILPINE MALEATE; INTERLEUKIN DERIVATIVE; METHIONINE; NR1 NMDA RECEPTOR; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; IMMUNOFLUORESCENCE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; ATHEROSCLEROSIS; BIOSYNTHESIS; CELL CULTURE; COMPLICATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HYPERHOMOCYSTEINEMIA; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; SPRAGUE DAWLEY RAT;

ANIMALS; ATHEROSCLEROSIS; C-REACTIVE PROTEIN; CELLS, CULTURED; DIZOCILPINE MALEATE; GENE EXPRESSION REGULATION; HOMOCYSTEINE; HYPERHOMOCYSTEINEMIA; INTERLEUKINS; MALE; MAP KINASE SIGNALING SYSTEM; METHIONINE; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; ONIUM COMPOUNDS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPEROXIDES; THENOYLTRIFLUOROACETONE;

EID: 84905845515     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2014.06.021     Document Type: Article

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