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Volumn 9, Issue 8, 2014, Pages

Cyclophilin a (CypA) interacts with NF-κB subunit, p65/RelA, and contributes to NF-κB activation signaling

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHILIN A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; CYCLOHEXIMIDE; CYCLOSPORIN; LACTONE; PROTEIN BINDING; RELA PROTEIN, MOUSE; SANGLIFEHRIN A; SPIRO COMPOUND;

EID: 84905833521     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096211     Document Type: Article
Times cited : (50)

References (39)
  • 1
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: Linking inflammation and immunity to cancer development and progression
    • DOI 10.1038/nri1703
    • Karin M, Greten FR (2005) NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 5:749-759. (Pubitemid 41400849)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 2
    • 67650724069 scopus 로고    scopus 로고
    • Regulation and function of NF-kappaB transcription factors in the immune system
    • Vallabhapurapu S, Karin M (2009) Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 27:693-733.
    • (2009) Annu Rev Immunol , vol.27 , pp. 693-733
    • Vallabhapurapu, S.1    Karin, M.2
  • 3
    • 0035174615 scopus 로고    scopus 로고
    • Series introduction: The transcription factor NF-kappaB and human disease
    • Baldwin AS Jr (2001) Series introduction: the transcription factor NF-kappaB and human disease. J Clin Invest 107:3-6.
    • (2001) J Clin Invest , vol.107 , pp. 3-6
    • Baldwin Jr., A.S.1
  • 4
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, Li ZW (2002) NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2:301-310. (Pubitemid 37328783)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.4 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.-W.4
  • 5
    • 33750454819 scopus 로고    scopus 로고
    • Mutations in the NF-kappaB signaling pathway: Implications for human disease
    • DOI 10.1038/sj.onc.1209939, PII 1209939
    • Courtois G, Gilmore TD (2006) Mutations in the NF-kappaB signaling pathway: implications for human disease. Oncogene 25:6831-6843. (Pubitemid 44657855)
    • (2006) Oncogene , vol.25 , Issue.51 , pp. 6831-6843
    • Courtois, G.1    Gilmore, T.D.2
  • 6
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-κB activity
    • DOI 10.1146/annurev.immunol.18.1.621
    • Karin M, Ben-Neriah Y (2000). Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu. Rev. Immunol 18:621-663. (Pubitemid 30365393)
    • (2000) Annual Review of Immunology , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 7
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-κB signaling
    • Hayden MS, Ghosh S (2008) Shared principles in NF-κB signaling. Cell 132:344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 8
    • 2342522110 scopus 로고    scopus 로고
    • Shaping the nuclear action of NF-kappaB
    • Chen LF, Greene WC (2004) Shaping the nuclear action of NF-kappaB. Nat Rev Mol Cell Biol 5:392-401.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 392-401
    • Chen, L.F.1    Greene, W.C.2
  • 10
    • 0034916613 scopus 로고    scopus 로고
    • p300/CBP proteins: HATs for transcriptional bridges and scaffolds
    • Chan HM, La Thangue NB (2001) p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J Cell Sci 114(Pt 13):2363-2373. (Pubitemid 32684792)
    • (2001) Journal of Cell Science , vol.114 , Issue.13 , pp. 2363-2373
    • Chan, H.M.1    La, T.N.B.2
  • 11
    • 79953319238 scopus 로고    scopus 로고
    • LRP16 Integrates into NF-κB Transcriptional Complex and Is Required for Its Functional Activation
    • Wu Z, Li Y, Li X, Ti D, Zhao Y, et al. (2011) LRP16 Integrates into NF-κB Transcriptional Complex and Is Required for Its Functional Activation. PLoS ONE 6:e18157.
    • (2011) PLoS ONE , vol.6
    • Wu, Z.1    Li, Y.2    Li, X.3    Ti, D.4    Zhao, Y.5
  • 12
    • 1242292029 scopus 로고    scopus 로고
    • Regulation of peptide bond cis/trans isomerization by enzyme catalysis and its implication in physiological processes
    • Fischer G, Aumüller T (2003) Regulation of peptide bond cis/trans isomerization by enzyme catalysis and its implication in physiological processes. Rev Physiol Biochem Pharmacol 148:105-150.
    • (2003) Rev Physiol Biochem Pharmacol , vol.148 , pp. 105-150
    • Fischer, G.1    Aumüller, T.2
  • 13
    • 0028890084 scopus 로고
    • Enzyme Assembly after de Novo Synthesis in Rabbit Reticulocyte Lysate Involves Molecular Chaperones and Immunophilins
    • Kruse M, Brunke M, Escher A, Szalay AA, Tropschug M, et al. (1995) Enzyme Assembly after de Novo Synthesis in Rabbit Reticulocyte Lysate Involves Molecular Chaperones and Immunophilins. J Biol Chem 270:2588-2594.
    • (1995) J Biol Chem , vol.270 , pp. 2588-2594
    • Kruse, M.1    Brunke, M.2    Escher, A.3    Szalay, A.A.4    Tropschug, M.5
  • 14
    • 0021159379 scopus 로고
    • Cyclophilin: A specific cytosolic binding protein for cyclosporin A
    • Handschumacher RE, Harding MW, Rice J, Drugge RJ, Speicher DW (1984) Cyclophilin: a specific cytosolic binding protein for cyclosporin A. Science 226:544-547. (Pubitemid 14018525)
    • (1984) Science , vol.226 , Issue.4674 , pp. 544-547
    • Handschumacher, R.E.1    Harding, M.W.2    Rice, J.3
  • 15
    • 0027323876 scopus 로고
    • Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: Roles of calcineurin binding and cellular location
    • Bram RJ, Hung DT, Martin PK, Schreiber SL, Crabtree GR (1993) Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporine A and FK506: roles of calcineurin binding and cellular location. Mol Cell Biol 13:4760-4769. (Pubitemid 23220381)
    • (1993) Molecular and Cellular Biology , vol.13 , Issue.8 , pp. 4760-4769
    • Bram, R.J.1    Hung, D.T.2    Martin, P.K.3    Schreiber, S.L.4    Crabtree, G.R.5
  • 16
    • 18644384463 scopus 로고    scopus 로고
    • Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine
    • Colgan J, Asmal M, Yu B, Luban J (2005) Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine. J Immunol 174:6030-6038. (Pubitemid 40663790)
    • (2005) Journal of Immunology , vol.174 , Issue.10 , pp. 6030-6038
    • Colgan, J.1    Asmal, M.2    Yu, B.3    Luban, J.4
  • 18
    • 67449113506 scopus 로고    scopus 로고
    • Suppression of NF-kappaB by cyclosporine A and tacrolimus (FK506) via induction of C/EBP family:Implication for unfolded protein response
    • Du S, Hiramatsu N, Hayakawa K, Kasai A, Okamura M, et al. (2009) Suppression of NF-kappaB by cyclosporine A and tacrolimus (FK506) via induction of C/EBP family:implication for unfolded protein response. J Immunol 182:7201-7211.
    • (2009) J Immunol , vol.182 , pp. 7201-7211
    • Du, S.1    Hiramatsu, N.2    Hayakawa, K.3    Kasai, A.4    Okamura, M.5
  • 19
    • 34548660854 scopus 로고    scopus 로고
    • Prolyl cis-trans isomerization as a molecular timer
    • DOI 10.1038/nchembio.2007.35, PII NCHEMBIO200735
    • Lu KP, Finn G, Lee TH, Nicholson LK (2007) Prolyl cis-trans isomerization as a molecular timer. Nat Chem Biol 3:619-629. (Pubitemid 47417709)
    • (2007) Nature Chemical Biology , vol.3 , Issue.10 , pp. 619-629
    • Lu, K.P.1    Finn, G.2    Lee, T.H.3    Nicholson, L.K.4
  • 21
    • 2642571741 scopus 로고    scopus 로고
    • Cyclophilin A is required for retinoic acid-induced neuronal differentiation in p19 cells
    • DOI 10.1074/jbc.M311406200
    • Song J, Lu Y-C, Yokoyama K, Rossi J, Chiu R (2004) Cyclophilin A is required for retinoic acid-induced neuronal differentiation in p19 cells. J Biol Chem 279:24414-24419. (Pubitemid 38725304)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.23 , pp. 24414-24419
    • Song, J.1    Lu, Y.-C.2    Yokoyama, K.3    Rossi, J.4    Chiu, R.5
  • 23
    • 38049125795 scopus 로고    scopus 로고
    • Cyclophilin A is required for CXCR4-mediated nuclear export of heterogenous nuclear ribonucleaoprotein A2 activation and nuclear translocation of ERK1/2, and chemotactic cell migration
    • Pan H, Luo C, Li R, Qiao A, Zhang L, et al. (2008) Cyclophilin A is required for CXCR4-mediated nuclear export of heterogenous nuclear ribonucleaoprotein A2 activation and nuclear translocation of ERK1/2, and chemotactic cell migration. J Biol Chem 283:623-637.
    • (2008) J Biol Chem , vol.283 , pp. 623-637
    • Pan, H.1    Luo, C.2    Li, R.3    Qiao, A.4    Zhang, L.5
  • 24
    • 68349148257 scopus 로고    scopus 로고
    • Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells
    • Bauer K, Kretzschmar AK, Cvijic H, Blumert C, Löffler D, et al., (2009) Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells. Oncogene 28:2784-2795.
    • (2009) Oncogene , vol.28 , pp. 2784-2795
    • Bauer, K.1    Kretzschmar, A.K.2    Cvijic, H.3    Blumert, C.4    Löffler, D.5
  • 25
    • 23444447275 scopus 로고    scopus 로고
    • Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from marcrophages
    • Kim H, Kim WJ, Jeon ST, Koh EM, Cha HS, et al., (2005) Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from marcrophages. Clin Immunol 116:217-224.
    • (2005) Clin Immunol , vol.116 , pp. 217-224
    • Kim, H.1    Kim, W.J.2    Jeon, S.T.3    Koh, E.M.4    Cha, H.S.5
  • 27
    • 78651275992 scopus 로고    scopus 로고
    • Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB
    • Sun S, Wang Q, Qiang A, Cheng C, Soo C, et al. (2011) Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB. J Neurooncol 101:1-14.
    • (2011) J Neurooncol , vol.101 , pp. 1-14
    • Sun, S.1    Wang, Q.2    Qiang, A.3    Cheng, C.4    Soo, C.5
  • 28
    • 41049102001 scopus 로고    scopus 로고
    • Preparation, culture, and immortalization of mouse embryonic fibroblasts
    • Xu J (2005) Preparation, culture, and immortalization of mouse embryonic fibroblasts. Curr Protoc Mol Biol 28:28.1.1-28.1.8.
    • (2005) Curr Protoc Mol Biol , vol.28
    • Xu, J.1
  • 29
    • 0036022137 scopus 로고    scopus 로고
    • Interaction of the retinoblastoma gene product, RB, with cyclophilin A negatively affects cyclosporin-inhibited NFAT signaling
    • DOI 10.1002/jcb.10253
    • Cui Y, Mirkia K, Fu Y-HF, Zhu L, Yokoyama KK, et al. (2002) Interaction of the Retinoblastoma Gene Product, RB, With Cyclophilin A Negatively Affects Cyclosporin-Inhibited NFAT Signaling. J Cell Biochem 86:630-641. (Pubitemid 34839965)
    • (2002) Journal of Cellular Biochemistry , vol.86 , Issue.4 , pp. 630-641
    • Cui, Y.1    Mirkia, K.2    Fu, Y.-H.F.3    Zhu, L.4    Yokoyama, K.K.5    Chiu, R.6
  • 30
    • 0346094059 scopus 로고    scopus 로고
    • Effects of Altered Expression and Localization of Cyclophilin A on Differentiation of p19 Embryonic Carcinoma Cells
    • DOI 10.1023/B:CEMN.0000005321.11544.cc
    • Chiu R, Rey O, Zheng JQ, Twiss JL, Song J, et al. (2003) Effects of Altered Expression and Localization of Cyclophilin A on Differentiation of p19 Embryonic Carcinoma Cells. Cell Mol Neurobiol 23:929-943. (Pubitemid 38063333)
    • (2003) Cellular and Molecular Neurobiology , vol.23 , Issue.6 , pp. 929-943
    • Chiu, R.1    Rey, O.2    Zheng, J.-Q.3    Twiss, J.L.4    Song, J.5    Pang, S.6    Yokoyama, K.K.7
  • 31
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in immune system
    • Li Q, Verma IM (2002) NF-kappaB regulation in immune system. Nat Rev Immunol 2:725-734.
    • (2002) Nat Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 32
    • 0034144377 scopus 로고    scopus 로고
    • Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52
    • Mamane Y, Sharma S, Petropoulos L, Lin R, Hiscott J (2000) Postranslational regulation of IRF-4 activity by the immunophilin FKBP52. Immunity 12:129-140. (Pubitemid 30398627)
    • (2000) Immunity , vol.12 , Issue.2 , pp. 129-140
    • Mamane, Y.1    Sharma, S.2    Petropoulos, L.3    Rongtuan, L.4    Hiscott, J.5
  • 33
    • 0347955360 scopus 로고    scopus 로고
    • Regulation of NF-kappaB Signaling by Pin1-Dependent Prolyl Isomerization and Ubiquitin-Mediated Proteolysis of p65/RelA
    • DOI 10.1016/S1097-2765(03)00490-8
    • Ryo A, Suizu F, Yoshida Y, Perrem K, Liou YC, et al., (2003) Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol Cell 12:1413-1426. (Pubitemid 38037011)
    • (2003) Molecular Cell , vol.12 , Issue.6 , pp. 1413-1426
    • Ryo, A.1    Suizu, F.2    Yoshida, Y.3    Perrem, K.4    Liou, Y.-C.5    Wulf, G.6    Rottapel, R.7    Yamaoka, S.8    Lu, K.P.9
  • 34
    • 77949894155 scopus 로고    scopus 로고
    • Role of cyclophilin A during oncogenesis
    • Lee J (2010) Role of cyclophilin A during oncogenesis. Arch Pharm Res 33:181-718.
    • (2010) Arch Pharm Res , vol.33 , pp. 181-718
    • Lee, J.1
  • 35
    • 71649105843 scopus 로고    scopus 로고
    • Cyclophilin A: Potential functions and therapeutic target for human cancer
    • Obchoei S, Wongkhan S, Wongkham C, Li M, Yao Q, et al (2009) Cyclophilin A: potential functions and therapeutic target for human cancer. Med Sci Monit 15:RA221-232.
    • (2009) Med Sci Monit , vol.15
    • Obchoei, S.1    Wongkhan, S.2    Wongkham, C.3    Li, M.4    Yao, Q.5
  • 36
    • 17844397949 scopus 로고    scopus 로고
    • The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
    • DOI 10.1215/S1152851704001061
    • Brat DJ, Bellail AC, Van Meir EG (2005) The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro Oncol 7:122-133. (Pubitemid 40590513)
    • (2005) Neuro-Oncology , vol.7 , Issue.2 , pp. 122-133
    • Brat, D.J.1    Bellail, A.C.2    Van Meir, E.G.3
  • 37
    • 74549167737 scopus 로고    scopus 로고
    • Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
    • Park EJ, Lee JH, Yu GY, He G, Ali SR, et al., (2010) Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 140:197-208.
    • (2010) Cell , vol.140 , pp. 197-208
    • Park, E.J.1    Lee, J.H.2    Yu, G.Y.3    He, G.4    Ali, S.R.5
  • 38
    • 84875771578 scopus 로고    scopus 로고
    • IL-1 and EGF regulate expression of genes important in inflammation and cancer
    • Kasza A (2013) IL-1 and EGF regulate expression of genes important in inflammation and cancer. Cytokine 62:22-33.
    • (2013) Cytokine , vol.62 , pp. 22-33
    • Kasza, A.1
  • 39
    • 0027071803 scopus 로고
    • Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition
    • Zydowsky LD, Etzkorn FA, Chang HY, Ferguson SB, Stolz LA, et al. (1992) Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporine A binding and calcineurin inhibition. Protein Sci 1:1092-1099. (Pubitemid 23016423)
    • (1992) Protein Science , vol.1 , Issue.9 , pp. 1092-1099
    • Zydowsky, L.D.1    Etzkorn, F.A.2    Chang, H.Y.3    Ferguson, S.B.4    Stolz, L.A.5    Ho, S.I.6    Walsh, C.T.7


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