Low-intensity pulsed ultrasound induces angiogenesis and ameliorates left ventricular dysfunction in a porcine model of chronic myocardial ischemia

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Hanawa, Kenichiro ^a   Ito, Kenta ^a   Aizawa, Kentaro ^a   Shindo, Tomohiko ^a   Nishimiya, Kensuke ^a   Hasebe, Yuhi ^a   Tuburaya, Ryuji ^a   Hasegawa, Hideyuki ^b   Yasuda, Satoshi ^c   Kanai, Hiroshi ^b   Shimokawa, Hiroaki ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; NOS3 PROTEIN, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CONTROLLED STUDY; GENE EXPRESSION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE BLOOD FLOW; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN CELL; ISCHEMIC HEART DISEASE; LOW INTENSITY PULSED ULTRASOUND THERAPY; NON INVASIVE PROCEDURE; NONHUMAN; PORCINE MODEL; SWINE; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BLOOD FLOW; CARDIAC MUSCLE; CELL LINE; ECHOCARDIOGRAPHY; ECHOGRAPHY; HEART LEFT VENTRICLE FUNCTION; HIGH-ENERGY SHOCK WAVE; MYOCARDIAL ISCHEMIA; PATHOLOGY; PIG; THERAPEUTIC USE; ULTRASOUND;

ANIMALS; CELL LINE; ECHOCARDIOGRAPHY; FIBROBLAST GROWTH FACTOR 2; HIGH-ENERGY SHOCK WAVES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MYOCARDIAL ISCHEMIA; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE SYNTHASE TYPE III; REGIONAL BLOOD FLOW; SWINE; ULTRASONIC WAVES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84905823864     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0104863     Document Type: Article

References (37)

1. Ruff CT, Braunwald E. (2011) The evolving epidemiology of acute coronary syndromes. Nat Rev Cardiol 8: 140-147.
2. Japanese Coronary Artery Disease (JCAD) Study Investigators. (2006) Current status of the background of patients with coronary artery disease in Japan. Circ J 70: 1256-1262.
3. Hata J, Kiyohara Y. (2013) Epidemiology of stroke and coronary artery disease in Asia. Circ J 77: 1923-1932.
4. Nishida T, Shimokawa H, Matsumoto Y, Takeshita A, Sunagawa K, et al. (2004) Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo. Circulation 110: 3055-3061. (Pubitemid 39491998)
5. Fukumoto Y, Ito A, Takeshita A, Sunagawa K, Shimokawa H, et al. (2006) Extracorporeal cardiac shock wave therapy ameliorates myocardial ischemia in patients with severe coronary artery disease. Coron Artery Dis 17: 63-70. (Pubitemid 44365923)
6. Ito K, Fukumoto Y, Shimokawa H. (2009) Extracorporeal shock wave therapy as a new and non-invasive angiogenic therapy. Tohoku J Exp Med 219: 1-9.
7. Kikuchi Y, Ito K, Kuriyama S, Tsuji I, Shimokawa H, et al. (2010) Double-blind and placebo-controlled study of the effectiveness and safety of extracorporeal cardiac shock wave therapy for severe angina pectoris. Circ J 74: 589-591.
8. Ito K, Fukumoto Y, Shimokawa H. (2011) Extracorporeal shock wave therapy for ischemic cardiovascular disorders. Am J Cardiovasc Drugs 11: 295-302.
9. ter Haar G. (2007) Therapeutic applications of ultrasound. Prog Biophys Mol Biol 93: 111-129.
10. Barzelai S, Sharabani-Yosef O, Walden R, Engelberg S, Scheinowitz M, et al. (2006) Low-intensity ultrasound induces angiogenesis in rat hind-limb ischemia. Ultrasound Med Biol 32: 139-145. (Pubitemid 41814869)
11. Mizrahi N, Seliktar D, Kimmel E. (2007) Ultrasound-induced angiogenic response in endothelial cells. Ultrasound Med Biol 33: 1818-1829. (Pubitemid 47632996)
12. Ramli R, Reher P, Harris M, Meghji S. (2009) The effect of ultrasound on angiogenesis: an in vivo study using the chick chorioallantoic membrane. Int J Oral Maxillofac Implants. 24: 591-596.
13. O'Konski MS, White FC, Longhurst J, Roth D, Bloor CM. (1987) Ameroid constriction of the proximal left circumflex coronary artery in swine: a model of limited coronary collateral circulation. Am J Cardiovasc Pathol 1: 69-77.
14. Roth DM, Maruoka Y, White FC, Longhurst JC, Bloor CM, et al. (1987) Development of coronary collateral circulation in left circumflex ameroid-occluded swine myocardium. Am J Physiol 253: H1279-1288.
15. Rentrop KP, Cohen M, Blanke H, Phillips RA. (1985) Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects. J Am Coll Cardiol 5: 587-592. (Pubitemid 15141963)
16. Prinzen FW, Bassingthwaighte JB. (2000) Blood flow distributions by microsphere deposition methods. Cardiovasc Res 45: 13-21.
17. Weaver ME, Pantely GA, Bristow JD, Ladley HD. (1986) A quantitative study of the anatomy and distribution of coronary arteries in swine in comparison with other animals and man. Cardiovasc Res 20: 907-17. (Pubitemid 17210511)
18. Bir SC, Xiong Y, Kevil CG, Luo J. (2012) Emerging role of PKA/eNOS pathway in therapeutic angiogenesis for ischaemic tissue diseases. Cardiovasc Res 95: 7-18.
19. Przybylski M. (2009) A review of the current research on the role of bFGF and VEGF in angiogenesis. J Wound Care 18: 516-519.
20. Zhang M, Shah AM. (2014) ROS signalling between endothelial cells and cardiac cells. Cardiovasc Res 102: 249-57.
21. Garin G, Mathews M, Berk BC. (2005) Tissue-resident bone marrow-derived progenitor cells: key players in hypoxia-induced angiogenesis. Circ Res 97: 955-957. (Pubitemid 41668905)
22. Xu P, Gul-Uludag H, Xing J, Swanson E, Chen J, et al. (2012) Low-intensity pulsed ultrasound-mediated stimulation of hematopoietic stem/progenitor cell viability, proliferation and differentiation in vitro. Biotechnol Lett 34: 1965-1973.
23. Toyama Y, Sasaki K, Chibana H, Itaya N, Imaizumi T, et al. (2012) Ultrasound stimulation restores impaired neovascularization-related capacities of human circulating angiogenic cells. Cardiovasc Res 95: 448-459.
24. Leri A, Kajstura J, Anversa P. (2011) Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biology. Circ Res 109: 941-961.
25. Reher P, Doan N, Bradnock B, Meghji S, Harris M. (1999) Effect of ultrasound on the production of IL-8, basic FGF and VEGF. Cytokine 11: 416-423. (Pubitemid 29259636)
26. Nakamura T, Fujihara S, Katsura T, Inubushi T, Tanaka E, et al. (2011) Low-intensity pulsed ultrasound reduces the inflammatory activity of synovitis. Ann Biomed Eng 39: 2964-2971.
27. Fu M, Sun CK, Shao PL, Leu S, Yip HK, et al. (2011) Extracorporeal shock wave therapy reverses ischemia-related left ventricular dysfunction and remodeling: molecular-cellular and functional assessment. PLoS One 6: e24342.
28. Shyy JY, Chien S. (2002) Role of integrins in endothelial mechanosensing of shear stress. Circ Res 91: 769-775. (Pubitemid 35285073)
29. Yu J, Bergaya S, Kurzchalia TV, Stan RV, Sessa WC, et al. (2006) Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels. J Clin Invest 116: 1284-1291.
30. Zaragoza C, Márquez S, Saura M. (2012) Endothelial mechanosensors of shear stress as regulators of atherogenesis. Curr Opin Lipidol 23: 446-452.
31. 2+ in ultrasound-elicited bioeffects: progress, perspectives and prospects. Drug Discov Today 15: 892-906.
32. Serizawa F, Ito K, Sato A, Shimokawa H, Satomi S, et al. (2012) Extracorporeal shock wave therapy improves the walking ability of patients with peripheral artery disease and intermittent claudication. Circ J 76: 1486-1493.
33. Serizawa F, Ito K, Sato A, Shimokawa H, Satomi S, et al. (2011) Extracorporeal shock wave therapy induces therapeutic lymphangiogenesis in a rat model of secondary lymphoedema. Eur J Vasc Endovasc Surg 42: 254-260.
34. Hayashi D, Kawakami K, Ito K, Shimokawa H, Tachi M, et al. (2012) Low-energy extracorporeal shock wave therapy enhances skin wound healing in diabetic mice: a critical role of endothelial nitric oxide synthase. Wound Repair Regen 20: 887-895.
35. Yamaya S, Ozawa H, Ito K, Shimokawa H, Itoi E, et al. (2014) Low-energy extracorporeal shock wave therapy promotes VEGF expression and neuroprotection and improves locomotor recovery after spinal cord injury. J Neurosurg (in press).
36. Uwatoku T, Ito K, Hizume T, Sunagawa K, Shimokawa H, et al. (2007) Extracorporeal cardiac shock wave therapy improves left ventricular remodeling after acute myocardial infarction in pigs. Coron Artery Dis 18: 397-404. (Pubitemid 47186841)
37. Ito Y, Ito K, Fukumoto Y, Yasuda S, Shimokawa H, et al. (2010) Cardiac shock wave therapy ameliorates left ventricular remodeling after myocardial ischemia-reperfusion injury in pigs in vivo. Coron Artery Dis 21: 304-11.