Clostridium difficile infection worsens the prognosis of ulcerative colitis

Canadian Journal of Gastroenterology and Hepatology

Volumn 28, Issue 7, 2014, Pages 373-380

  Negrón, María E ^a   Barkema, Herman W ^a   Rioux, Kevin ^a   De Buck, Jeroen ^a   Checkley, Sylvia ^a   Proulx, Marie Claude ^a   Frolkis, Alexandra ^a   Beck, PaulL ^a   Dieleman, Levinus A ^a,b   Panaccione, Remo ^a   Ghosh, Subrata ^a   Kaplan, Gilaad G ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Clostridium difficile; Colectomy; Postoperative complications; Ulcerative colitis

Indexed keywords

ADULT; ARTICLE; CANADA; CLOSTRIDIUM DIFFICILE INFECTION; COLON RESECTION; CONTROLLED STUDY; EARLY DIAGNOSIS; EMERGENCY SURGERY; FEMALE; HOSPITAL ADMISSION; HUMAN; INFECTIOUS COMPLICATION; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OUTCOME ASSESSMENT; POPULATION BASED CASE CONTROL STUDY; POSTOPERATIVE INFECTION; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; ULCERATIVE COLITIS; AGED; ALBERTA; CASE CONTROL STUDY; COLITIS, ULCERATIVE; DISEASE COURSE; ENTEROCOLITIS, PSEUDOMEMBRANOUS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; PEPTOCLOSTRIDIUM DIFFICILE; POSTOPERATIVE COMPLICATIONS; REGRESSION ANALYSIS; STATISTICS AND NUMERICAL DATA;

ADULT; AGED; ALBERTA; CASE-CONTROL STUDIES; CLOSTRIDIUM DIFFICILE; COLECTOMY; COLITIS, ULCERATIVE; DISEASE PROGRESSION; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FEMALE; HUMANS; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; REGRESSION ANALYSIS;

EID: 84905820004     PISSN: 22912789     EISSN: 22912797     Source Type: Journal    
DOI: 10.1155/2014/914303     Document Type: Article

References (33)

1. Molodecky NA, Soon IS, Rabi DM, et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterol 2012;142:46-54.
2. Kaplan GG, Seow CH, Ghosh S, et al. Decreasing colectomy rates for ulcerative colitis: A population-based time trend study. Am J Gastroenterol 2012;12:1879-87.
3. Frolkis AD, Dykeman J, Negron ME, et al. Risk of surgery for inflammatory bowel diseases has decreased over time: A systematic review and meta-analysis of population-based studies. Gastroenterol 2013;145:996-1006.
4. de Silva S, Ma C, Proulx MC, et al. Postoperative complications and mortality following colectomy for ulcerative colitis. Clin Gastroenterol Hepatol 2011;11:972-80.
5. Soon IS, Wrobel I, deBruyn JC, et al. Postoperative complications following colectomy for ulcerative colitis in children. J Pediatr Gastroenterol Nutr 2012;54:763-8.
6. Ricciardi R, Ogilvie JW, Roberts PL, Marcello PW, Concannon TW, Baxter NN. Epidemiology of Clostridium difficile colitis in hospitalized patients with inflammatory bowel diseases. Dis Colon Rectum 2009;52:40-5.
7. Chandler RE, Hedberg K, Cieslak PR. Clostridium difficile associated disease in Oregon: Increasing incidence and hospital-level risk factors. Infect Control Hosp Epidemiol 2007;28:116-22. (Pubitemid 46374150)
8. Hubert B, Loo VG, Bourgault AM, et al. A portrait of the geographic dissemination of the Clostridium difficile North American pulsed-field type 1 strain and the epidemiology of C. difficile-associated disease in Quebec. Clin Infect Dis 2007;44:238-44. (Pubitemid 46079988)
9. Ananthakrishnan AN. Clostridium difficile infection: Epidemiology, risk factors and management. Nat Rev Gastroenterol Hepatol 2011;8:17-26.
10. Berg AM, Kelly CP, Farraye FA. Clostridium difficile infection in the inflammatory bowel disease patient. Inflamm Bowel Dis 2013;19:194-204.
11. Nguyen GC, Kaplan GG, Harris ML, Brant SR. A national survey of the prevalence and impact of Clostridium difficile infection among hospitalized inflammatory bowel disease patients. Am J Gastroenterol 2008;103:1443-50. (Pubitemid 351813903)
12. Issa M, Vijayapal A, Graham MB, et al. Impact of Clostridium difficile on inflammatory bowel disease. Clin Gastroenterol Hepatol 2007;5:345-51. (Pubitemid 46401531)
13. Ananthakrishnan AN, McGinley EL, Saeian K, Binion DG. Temporal trends in disease outcomes related to Clostridium difficile infection in patients with inflammatory bowel disease. Inflamm Bowel Dis 2011;17:976-83.
14. Ananthakrishnan AN, McGinley EL, Binion DG. Excess hospitalisation burden associated with Clostridium difficile in patients with inflammatory bowel disease. Gut 2008;57:205-10. (Pubitemid 351158048)
15. Alberta Health Services. Alberta Health Services Annual Report, April 1, 2009-March 31, 2010. 〈www.albertahealthservices.ca/Publications/ahs-pub- annual-rpt.pdf〉 (Accessed November 1, 2012).
16. Ma C, Crespin M, Proulx MC, et al. Postoperative complications following colectomy for ulcerative colitis: A validation study. BMC Gastroenterol 2012;12:39.
17. Dindo D, Demartines N, Clavien P-A. Classification of surgical complications. Ann Surg 2004;240:205-13.
18. Vandenbroucke JP, von Elm E, Altman DG, et al. Strengthening the reporting of observational studies in epidemiology (STROBE): Explanation and elaboration. PLoS Med 2007;4:e297.
19. Murthy SK, Steinhart AH, Tinmouth J, et al. Impact of Clostridium difficile colitis on 5-year health outcomes in patients with ulcerative colitis. Aliment Pharmacol Ther 2012;36:1032-9.
20. Navaneethan U, Mukewar S, Venkatesh PG, et al. Clostridium difficile infection is associated with worse long term outcome in patients with ulcerative colitis. J Crohns Colitis 2012;6:330-6.
21. Kariv R, Navaneethan U, Venkatesh PG, Lopez R, Shen B. Impact of Clostridium difficile infection in patients with ulcerative colitis. J Crohns Colitis 2011;5:34-40.
22. Kaneko T, Matsuda R, Taguri M, et al. Clostridium difficile infection in patients with ulcerative colitis: Investigations of risk factors and efficacy of antibiotics for steroid refractory patients. Clin Res Hepatol Gastroenterol 2011;35:315-20.
23. Molodecky NA, Panaccione R, Ghosh S, Barkema HW, Kaplan GG. Challenges associated with identifying the environmental determinants of the inflammatory bowel diseases. Inflamm Bowel Dis 2011;17:1792-9.
24. Kaplan GG, McCarthy EP, Ayanian JZ, Korzenik J, Hodin R, Sands BE. Impact of hospital volume on postoperative morbidity and mortality following a colectomy for ulcerative colitis. Gastroenterol 2008;134:680-7.
25. Sundram F, Guyot A, Carboo I, Green S, Lilaonitkul M, Scourfield A. Clostridium difficile ribotypes 027 and 106: Clinical outcomes and risk factors. J Hospl Infect 2009;72:111-8.
26. Goodhand JR, Alazawi W, Rampton DS. Systematic review: Clostridium difficile and inflammatory bowel disease. Aliment Pharmacol Ther 2011;33:428-41.
27. Yanai H, Nguyen GC, Yun L, et al. Practice of gastroenterologists in treating flaring inflammatory bowel disease patients with Clostridium difficile: Antibiotics alone or combined antibiotics/immunomodulators? Inflamm Bowel Dis 2011;17:1540-6.
28. Kaplan GG, Hubbard J, Panaccione R, et al. Risk of comorbidities on postoperative outcomes in patients with inflammatory bowel disease. Arch Surg 2011;146:959-64.
29. Tacconelli E, De Angelis G, Cataldo MA, et al. Antibiotic usage and risk of colonization and infection with antibiotic-resistant bacteria: A hospital population-based study. Antimicrob Agents Chemother 2009;53:4264-9.
30. Moore R, Pothoulakis C, LaMont JT, Carlson S, Madara JL. C. difficile toxin A increases intestinal permeability and induces Cl- secretion. Am J Physiol Gastrointest Liver Physiol 1990;259:G165-G72.
31. Hetch G, Charalabos P, LaMont JT, Madara JL. Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers. J Clin Invest 1988;82:1516-24. (Pubitemid 19007753)
32. Feltis BA, Kim AS, Kinneberg KM, et al. Clostridium difficile toxins may augment bacterial penetration of intestinal epithelium. Arch Surg 1999;134:1235-42.
33. Schulz KF, Grimes DA. Case-control studies: Research in reverse. Lancet 2002;359:431-4. (Pubitemid 34158958)