Absolute Level of Gamma Synchrony is Increased in FirstEpisode Schizophrenia during Face Processing

Journal of Experimental Psychopathology

Volumn 3, Issue 4, 2012, Pages 702-723

  Silverstein, Steven M ^a   All, Sherrie D ^a   Thompson, Judy L ^b   Williams, Leanne M ^c,d,f,g   Whitford, Thomas J ^c   Nagy, Marie ^c   Flynn, Gary ^c   Harris, Anthony WF ^c,d   Galletly, Cherrie ^e   Gordon, Evian ^c,d,f,g  

^a UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c UNIVERSITY OF SYDNEY   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

^e UNIVERSITY OF ADELAIDE   (Australia)

^f Brain Resource International Database   (Australia)

^g NONE   (United States)

Author keywords

Brain Research and Integrative Neuroscience Network (BRAINnet); EEG; face processing; first episode; gamma synchrony; schizophrenia

Indexed keywords

EID: 84905815718     PISSN: None     EISSN: 20438087     Source Type: Journal    
DOI: 10.5127/jep.023311     Document Type: Article

References (66)

1. Anilkumar A. P. P., Kumari V., Mehrotra R., Aasen I., Mitterschiffthaler M. T., & Sharma T. (2008). An fMRI study of face encoding and recognition in first-episode schizophrenia. Acta Neuropsychiatrica, 20, 129-138. http://dx.doi.org/10.1111/j.1601-5215.2008.00280.x
2. Baldeweg T., Spence S., Hirsch S. R., & Gruzelier J. (1998). Gamma-band electroencephalographic oscillations in a patient with somatic hallucinations. Lancet, 352, 620-621. http://dx.doi.org/10.1016/S0140-6736(05)79575-1
3. Butler P. D., Tambini A., Yovel G., Jalbrzikowski M., Ziwich R., Silipo G., … Javitt D. C. (2008). What's in a face? Effects of stimulus duration and inversion on face processing in schizophrenia. Schizophrenia Research 103, 283-292. http://dx.doi.org/10.1016/j.schres.2008.03.007
4. Chen Y., Norton D., McBain R., Ongur D., & Heckers S. (2008). Visual and cognitive processing of face information in schizophrenia: Detection, discrimination and working memory. Schizophrenia Research, 107, 92-98. http://dx.doi.org/10.1016/j.schres.2008.09.010
5. Chen Y., Norton D., Ongur D., & Heckers S. (2008). Inefficient face detection in schizophrenia. Schizophrenia Bulletin, 34, 367-374. http://dx.doi.org/10.1093/schbul/sbm071
6. Clementz B. A., Blumenfeld L. D., & Cobb S. (1997). The gamma band response may account for poor P50 suppression in schizophrenia. Neuroreport, 8, 3889-3893. http://dx.doi.org/10.1097/00001756-199712220-00010
7. Dong W., Liu L., & Zou L. (2006). Face perception in schizophrenia: A functional magnetic resonance imaging study. Chinese Mental Health Journal, 20, 775-778.
8. Fakra E., Salgado-Pineda P., Delaveau P., Hariri A. R., & Blin O. (2008). Neural bases of different cognitive strategies for facial affect processing in schizophrenia. Schizophrenia Research, 100, 191-205. http://dx.doi.org/10.1016/j.schres.2007.11.040
9. Farrow T. F., Whitford T. J., Williams L. M., Gomes L., & Harris A. W. (2005). Diagnosis-related regional gray matter loss over two years in first episode schizophrenia and bipolar disorder. Biological Psychiatry, 58, 713-723. http://dx.doi.org/10.1016/j.biopsych.2005.04.033
10. First M. B., Spitzer R. L., Gibbon M., & Williams J. B. (1994). Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Washington, DC: American Psychiatric Press.
11. Flynn G., Alexander D., Harris A., Whitford T., Wong W., Galletly C., … Williams L. M. (2008). Increased absolute magnitude of gamma synchrony in first-episode psychosis. Schizophrenia Research. 105, 262-271. http://dx.doi.org/10.1016/j.schres.2008.05.029
12. Gandal M. J., Edgar J. C., Klook K., & Siegel S. J. (2012). Gamma synchrony: Towards a translational biomarker for the treatment-resistant symptoms of schizophrenia. Neuropharmacology. 62(3): 1504-18. http://dx.doi.org/10.1016/j.neuropharm.2011.02.007
13. Gold J. M., Fuller R. L., Robinson B. M., Braun E. L., & Luck S. J. (2007). Impaired top-down control of visual search in schizophrenia. Schizophrenia Research, 94, 148-155. http://dx.doi.org/10.1016/j.schres.2007.04.023
14. Gordon E. (2003). Integrative neuroscience. Neuropsychopharmacology, 28(Suppl 1), S2-8. http://dx.doi.org/10.1038/sj.npp.1300136
15. Gordon E., Barnett K. J., Cooper N. J., & Tran N. (2008). Williams LM, An “integrative neuroscience” platform: application to profiles of negativity and positivity bias. Journal of Integrative Neuroscience, 7, 345-366. http://dx.doi.org/10.1142/S0219635208001927
16. Gordon E., Cooper N., Rennie C., Hermens D., & Williams L. M. (2005). Integrative neuroscience: the role of a standardized database. Clinical EEG and Neuroscience, 36, 64-75. http://dx.doi.org/10.1177/155005940503600205
17. Gordon E., Williams L. M., Haig A. R., Bahramali H., Wright J., & Meares R. (2001). Symptom profile and ‘gamma’ processing in schizophrenia. Cognitive Neuropsychiatry, 6, 7-19. http://dx.doi.org/10.1080/13546800042000016
18. Gratton G., Coles M. G., & Donchin E. (1983). A new method for off-line removal of ocular artifact. Electroencephalography and Clinical Neurophysiology, 55, 468-484. http://dx.doi.org/10.1016/0013-4694(83)90135-9
19. Green M. F., Penn D. L., Bentall R., Carpenter W. T., Gaebel W., Gur R. C., … Heinssen R. 2008. Social cognition in schizophrenia: An NIMH workshop on definitions, assessment, and research opportunities. Schizophrenia Bulletin, 34, 1211-1220. http://dx.doi.org/10.1093/schbul/sbm145
20. Gur R. C., Sara R., Hagendoorn M., Marom O., Hughett P., Macy L., … Gur R. E. (2002). A method for obtaining 3-dimensional facial expressions and its standardization for use in neurocognitive studies. Journal of Neuroscience Methods, 115, 137-143. http://dx.doi.org/10.1016/S0165-0270(02)00006-7
21. Haig A. R., Gordon E., De Pascalis V., Meares R. A., Bahramali H., & Harris A. (2000). Gamma activity in schizophrenia: evidence of impaired network binding? Clinical Neurophysiology, 111, 1461-1468. http://dx.doi.org/10.1016/S1388-2457(00)00347-3
22. Hermann M. J., Ellgring H., & Fallgatter A. J. (2004). Early-stage face processing dysfunction in patients with schizophrenia. American Journal of Psychiatry, 161, 915-917. http://dx.doi.org/10.1176/appi.ajp.161.5.915
23. Herrmann M. J., Reif A., Jabs B. E., Jacob C., & Fallgatter A. J. (2006). Facial affect decoding in schizophrenic disorders: a study using event-related potentials. Psychiatry Research, 141, 247-252. http://dx.doi.org/10.1016/j.psychres.2005.09.015
24. Hickie I., Hadzi-Pavlovic D., Scott E., Davenport T., Koschera A., & Naismith S. (1998). SPHERE: A National Depression Project. Australasian Psychiatry, 6, 248-250. http://dx.doi.org/10.3109/10398569809084854
25. Kanwisher N. (2004). The ventral visual object pathway in humans: Evidence from fMRI. In Chalupa L. M., Werner J. S. (Eds.), The Visual Neurosciences. Cambridge, MA: The MIT Press.
26. Kay S. R., Fiszbein A., & Opler L. A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13, 261-276.
27. Kikuchi M., Hashimoto T., Nagasawa T., Hirosawa T., Minabe Y., Yoshimura M., … Koenig T. (2011). Frontal areas contribute to reduced global coordination of resting-state gamma activities in drug-naïve patients with schizophrenia. Schizophrenia Research, 130, 187-194. http://dx.doi.org/10.1016/j.schres.2011.06.003
28. Kwon J. S., O'Donnell B. F., Wallenstein G. V., Greene R. W., Hirayasu Y., Nestor P. G., … McCarley R. W. (1999). Gamma frequency-range abnormalities to auditory stimulation in schizophrenia. Archives of General Psychiatry, 56, 1001-1005. http://dx.doi.org/10.1001/archpsyc.56.11.1001
29. Lange K., Williams L. M., Young A. W., Bullmore E. T., Brammer M. J., Williams S. C., … Phillips M. L. (2003). Task instructions modulate neural responses to fearful facial expressions. Biological Psychiatry, 53, 226-232. http://dx.doi.org/10.1016/S0006-3223(02)01455-5
30. Latikka J., Kuurne T., & Eskola H. (2001). Conductivity of living intracranial tissues. Physics in Medicine and Biology, 46(6), 1611-1616. http://dx.doi.org/10.1088/0031-9155/46/6/302
31. Lee K. H., Williams L. M., Breakspear M., & Gordon E. (2003). Synchronous gamma activity: a review and contribution to an integrative neuroscience model of schizophrenia. Brain Research Reviews, 41, 57-78. http://dx.doi.org/10.1016/S0165-0173(02)00220-5
32. Lee K. H., Williams L. M., Haig A., Goldberg E., & Gordon E. (2001). An integration of 40 Hz gamma and phasic arousal: novelty and routinization processing in schizophrenia. Clinical Neurophysiology, 112, 1499-1507. http://dx.doi.org/10.1016/S1388-2457(01)00584-3
33. Leitman D. I., Loughead J., Wolf D. H., Ruparel K., Kohler C. G., Elliott M. A., … Gur R. C. (2008). Abnormal superior temporal connectivity during fear perception in schizophrenia. Schizophrenia Bulletin 34, 673-678. http://dx.doi.org/10.1093/schbul/sbn052
34. Llinas R. R., Ribary U., Jeanmonod D., Kronberg E., & Mitra P. P. (1999). Thalamocortical dysrhythmia: A neurological and neuropsychiatric syndrome characterized by magnetoencephalography. Proceedings of the National Academy of Sciences USA, 96, 15222-15227. http://dx.doi.org/10.1073/pnas.96.26.15222
35. Loffler G., Yourganov G., Wilkinson F., & Wilson H. R. (2005). fMRI evidence for the neural representation of faces. Nature Neuroscience, 8, 1386-1390. http://dx.doi.org/10.1038/nn1538
36. Maurer D., O'Craven K. M., Le Grand R., Mondloch C. J., Springer M. V., Lewis T. L., & Grady C. L. (2007). Neural correlates of processing facial identify based on features versus their spacing. Neuropsychologia, 45, 1438-1451. http://dx.doi.org/10.1016/j.neuropsychologia.2006.11.016
37. Mulert C., Kirsch V., Pascual-Marqui R., McCarley R. W., & Spencer K. M. (2011). Long-range synchrony of gamma oscillations and auditory hallucination symptoms in schizophrenia. International Journal of Psychophysiology, 79, 55-63. http://dx.doi.org/10.1016/j.ijpsycho.2010.08.004
38. Nunez P. L., Srinivasan R., Westdorp A. F., Wijesinghe R. S., Tucker D. M., Silberstein R. B., & Cadusch P. J. (1997). EEG coherency I: Statistics, reference electrode, volume conduction, Laplacians, cortical imaging, and interpretation at multiple scales. Electroencephalography and Clinical Neurophysiology, 103, 516-527.
39. Obayashi C., Nakashima T., Onitsuka T., Maekawa T., Hirano Y., Hirano S., … Tobimatsu S. (2009). Decreased spatial frequency sensitivities for processing faces in male patients with chronic schizophrenia. Clinical Neurophysiology, 120, 1525-1533. http://dx.doi.org/10.1016/j.clinph.2009.06.016
40. Paul R. H., Lawrence J., Williams L. M., Richard C. C., Cooper N., & Gordon E. (2005). Preliminary validity of “integneuro”: a new computerized battery of neurocognitive tests. International Journal of Neuroscience, 115, 1549-67. http://dx.doi.org/10.1080/00207450590957890
41. Peled A. (1999). Multiple constraint organization in the brain: A theory for schizophrenia. Brain Research Bulletin, 49, 245-250. http://dx.doi.org/10.1016/S0361-9230(99)00048-9
42. Phillips W. A., & Silverstein S. M. (2003). Convergence of biological and psychological perspectives on cognitive coordination in schizophrenia. Behavioral and Brain Sciences, 26, 65-82, discussion 82–137. http://dx.doi.org/10.1017/S0140525X03000025
43. Phillips W. A., & Singer W. (1997). In search of common foundations for cortical computation. Behavioral and Brain Sciences, 20, 657-683, discussion 683–722. http://dx.doi.org/10.1017/S0140525X9700160X
44. Phillips S., & Takeda Y. (2009). Greater frontal-parietal synchrony at low gamma-band frequencies for inefficient than efficient visual search in human EEG. International Journal of Psychophysiology, 73, 350-354. http://dx.doi.org/10.1016/j.ijpsycho.2009.05.011
45. Rodriguez E., George N., Lachaux J. P., Martinerie J., Renault B., & Varela F. J. (1999). Perception's shadow: long-distance synchronization of human brain activity. Nature, 397, 430-433. http://dx.doi.org/10.1038/17120
46. Shin Y. W., Na M. H., Ha T. H., Kang D. H., Yoo S. Y., & Kwon J. S. (2008). Dysfunction in configural face processing in patients with schizophrenia. Schizophrenia Bulletin, 34, 538-543. http://dx.doi.org/10.1093/schbul/sbm118
47. Silverstein S. M., All S. D., Kasi R., Berten S., Essex B., Lathrop K. L., & Little D. M. (2010). Increased fusiform area activation in schizophrenia during processing of spatial frequency-degraded faces as revealed by fMRI. Psychological Medicine, 40, 1159-1169. http://dx.doi.org/10.1017/S0033291709991735
48. Silverstein S. M., Berten S., Essex B., All S. D., Kasi R., & Little D. M. (2010). Perceptual organization and visual search processes during target detection task performance in schizophrenia, as revealed by fMRI. Neuropsychologia, 48, 2886-2893. http://dx.doi.org/10.1016/j.neuropsychologia.2010.05.030
49. Silverstein S. M., & Keane B. P. (2011). Perceptual organization impairment in schizophrenia and associated brain mechanisms; review of research from 2005–2010. Schizophrenia Bulletin, 37, 690-699. http://dx.doi.org/10.1093/schbul/sbr052
50. Silverstein S. M., Knight R. A., Schwarzkopf S. B., West L. L., Osborn L. M., & Kamin D. (1996). Stimulus configuration and context effects in perceptual organization in schizophrenia. Journal of Abnormal Psychology, 105, 410-420. http://dx.doi.org/10.1037/0021-843X.105.3.410
51. Silverstein S. M., Wallace C. J., & Schenkel L. S. (2005). The micro-module learning tests: work-sample assessments of responsiveness to skills training. Schizophrenia Bulletin, 31, 73-83. http://dx.doi.org/10.1093/schbul/sbi008
52. Singer W., & Gray C. M. (1995). Visual feature integration and the temporal correlation hypothesis. Annual Review of Neuroscience, 18, 555-586. http://dx.doi.org/10.1146/annurev.ne.18.030195.003011
53. Spitzer R. L., Kroenke K., & Williams J. B. (1999). Validation and utility of a self-report version of PRIME-MD: The PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. Journal of the American Medical Association, 282, 1737-1744. http://dx.doi.org/10.1001/jama.282.18.1737
54. Turetsky B. I., Kohler C. G., Indersmitten T., Bhati M. T., Charbonnier D., & Gur R. C. (2007). Facial emotion recognition in schizophrenia: when and why does it go awry? Schizophrenia Research, 94, 253-263. http://dx.doi.org/10.1016/j.schres.2007.05.001
55. Uhlhaas P. J., Haenschel C., Nikolic D., & Singer W. (2008). The role of oscillations and synchrony in cortical networks and their putative relevance for the pathophysiology of schizophrenia. Schizophrenia Bulletin, 34, 927-943. http://dx.doi.org/10.1093/schbul/sbn062
56. Uhlhaas P. J., Linden D. E., Singer W., Haenschel C., Lindner M., Maurer K, & Rodriguez E. (2006). Dysfunctional long-range coordination of neural activity during Gestalt perception in schizophrenia. Journal of Neuroscience, 26, 8168-8175. http://dx.doi.org/10.1523/JNEUROSCI.2002-06.2006
57. Uhlhaas P. J., Phillips W. A., & Silverstein S. M. (2005). The course and clinical correlates of dysfunctions in visual perceptual organization in schizophrenia during the remission of psychotic symptoms. Schizophrenia Research, 72, 183-192. http://dx.doi.org/10.1016/j.schres.2004.11.005
58. Uhlhaas P. J., & Silverstein S. M. (2005). Perceptual organization in schizophrenia spectrum disorders: A review of empirical research and associated theories. Psychological Bulletin, 131, 618-632. http://dx.doi.org/10.1037/0033-2909.131.4.618
59. Uhlhaas P. J., & Singer W. (2010). Abnormal neural oscillations and synchrony in schizophrenia. Nature Reviews Neuroscience, 11, 100-113. http://dx.doi.org/10.1038/nrn2774
60. Williams L. M. (2008). Voxel-based morphometry in schizophrenia: implications for neurodevelopmental connectivity models, cognition and affect. Expert Review of Neurotherapeutics, 8, 1049-1065. http://dx.doi.org/10.1586/14737175.8.7.1049
61. Williams L. M., Kemp A. H., Felmingham K., Liddell B. J., Palmer D. M., & Bryant R. A. (2007). Neural biases to covert and overt signals of fear: dissociation by trait anxiety and depression. Journal of Cognitive Neuroscience, 19, 1595-1608. http://dx.doi.org/10.1162/jocn.2007.19.10.1595
62. Williams L. M., Loughland C. A., Gordon E., & Davidson D. (1999). Visual scanpaths in schizophrenia: is there a deficit in face recognition? Schizophrenia Research, 40, 189-199. http://dx.doi.org/10.1016/S0920-9964(99)00056-0
63. Williams L. M., Palmer D., Liddell B. J., Song L., & Gordon E. (2006). The ‘when’ and ‘where’ of perceiving signals of threat versus non-threat. Neuroimage, 31, 458-467. http://dx.doi.org/10.1016/j.neuroimage.2005.12.009
64. Williams L. M., Whitford T., Nagy M., Flynn G., Harris A., Silverstein S., & Gordon E. (2009). Emotion-elicited gamma synchrony in patients with first-episode schizophrenia: a neural correlate of social cognition outcomes. Journal of Psychiatry and Neuroscience, 34, 303-313.
65. Woods S. W. (2003). Chlorpromazine equivalent doses for the newer atypical antipsychotics. Journal of Clinical Psychiatry, 64, 663-667. http://dx.doi.org/10.4088/JCP.v64n0607
66. Yoon J. H., D'Esposito M., & Carter C. S. (2006). Preserved function of the fusiform face area in schizophrenia as revealed by fMRI. Psychiatry Research 148, 205-216. http://dx.doi.org/10.1016/j.pscychresns.2006.06.002