Testing albendazole resistance in Fasciola hepatica: Validation of an egg hatch test with isolates from South America and the United Kingdom

Journal of Helminthology

Volumn 88, Issue 3, 2014, Pages 286-292

  Canevari, J ^a   Ceballos, L ^a   Sanabria, R ^b   Romero, J ^b   Olaechea, F ^c   Ortiz, P ^d   Cabrera, M ^d   Gayo, V ^e   Fairweather, I ^f   Lanusse, C ^a   Alvarez, L ^a  

^a UNIVERSIDAD NACIONAL DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES   (Argentina)

^b UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^c Inst Nac de Tecnol Agropecuaria   (Argentina)

^d UNIVERSIDAD NACIONAL DE CAJAMARCA   (Peru)

^e DILAVE   (Uruguay)

^f QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE; ANTHELMINTIC AGENT;

ARTICLE; CAJAMARCA; CEDIVE; CONTROLLED STUDY; CULLOMPTON; DRUG RESISTANCE; DRUG SCREENING; EGG HATCH TEST; FASCIOLA HEPATICA; HATCHING; IN VITRO STUDY; INTA BARILOCHE; MICROORGANISM DETECTION; NONHUMAN; PARASITE ISOLATION; RIO CHICO; RUBINO; SOUTH AMERICA; UNITED KINGDOM; ANIMAL; DRUG EFFECTS; DRUG SENSITIVITY; EVALUATION STUDY; PHYSIOLOGY; PROCEDURES; RABBIT; TEMPERATURE; TIME; ZYGOTE;

ALBENDAZOLE; ANIMALS; ANTHELMINTICS; DRUG RESISTANCE; FASCIOLA HEPATICA; GREAT BRITAIN; PARASITIC SENSITIVITY TESTS; RABBITS; SOUTH AMERICA; TEMPERATURE; TIME FACTORS; ZYGOTE;

EID: 84905671006     PISSN: 0022149X     EISSN: 14752697     Source Type: Journal    
DOI: 10.1017/S0022149X13000163     Document Type: Article

References (38)

1. Alvarez, L., Imperiale, F., Sánchez, S. & Lanusse, C. (2000) In vivo and ex vivo uptake of albendazole and albendazole sulphoxide by Haemonchus contortus and Fasciola hepatica in sheep. Veterinary Parasitology 94, 75-89.
2. Alvarez, L., Moreno, G., Moreno, L., Ceballos, L., Shaw, L., Fairweather, I. & Lanusse, C. (2009) Comparative assessment of albendazole and tricla-bendazole ovicidal activity on Fasciola hepatica eggs. Veterinary Parasitology 164, 211-216.
3. Boray, J., Crowfoot, P., Strong, M., Allison, J., Schellenbaum, M., von Orelli, M. & Sarasin, G. (1983) Treatment of immature and mature Fasciola hepatica infections in sheep with triclabendazole. Veterinary Record 113, 315-317.
4. Buchanan, J.F., Fairweather, I., Brennan, G.P., Trudgett, A. & Hoey, E.M. (2003) Fasciola hepatica: surface and internal tegumental changes induced by treatment in vitro with the sulphoxide metabolite of albendazole ('Valbazen'). Parasitology 126, 141-153.
5. Coles, C.G. & Stafford, K.A. (2001) Activity of oxyclozanide, nitroxinil, clorsulon, and albendazol against adult triclabendazole-resistant Fasciola hepatica. Veterinary Record 148, 723-724.
6. Coles, C.G., Jackson, F., Pomroy, W., Prichard, R., von Samson-Himmelstjerna, G., Silvestre, A., Taylor, M. & Vercruysse, J. (2006) The detection of anthelmin-tic resistance in nematodes of veterinary importance. Veterinary Parasitology 136, 167-185.
7. Coles, G. & Briscoe, M. (1978) Benzimidazoles and fluke eggs. Veterinary Record 103, 360-361.
8. Devine, C., Brennan, G.P., Lanusse, C.E., Alvarez, L.I., Trudgett, A., Hoey, E. & Fairweather, I. (2010) Inhibition of cytochrome P450-mediated metabolism enhances ex vivo susceptibility of Fasciola hepatica to triclabendazole. Parasitology 137, 871-880.
9. Devine, C., Brennan, G.P., Lanusse, C.E., Alvarez, L.I., Trudgett, A., Hoey, E. & Fairweather, I. (2012) Potentiation of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica following its co-administration with the metabolic inhibitor, ketoconazole. Veterinary Parasitology 184, 37-47.
10. Fairweather, I. (2005) Triclabendazole: new skills to unravel an old(ish) enigma. Journal of Helminthology 79, 227-234.
11. Fairweather, I. (2011a) Liver fluke isolates: a question of provenance. Veterinary Parasitology 176, 1-8.
12. Fairweather, I. (2011b) Reducing the future threat from (liver) fluke: realistic prospect or quixotic fantasy? Veterinary Parasitology 180, 133-143.
13. Fairweather, I., McShane, D.D., Shaw, L., Ellison, S.E., O'Hagan, N.T., York, E.A., Trudgett, A. & Brennan, G.P. (2012) Development of an egg hatch assay for the diagnosis of triclabendazole resistance in Fasciola hepatica: proof of concept. Veterinary Parasitology 183, 249-259.
14. Flanagan, A.M., Forster, H.W., Gordon, F., Hanna, A., McCoy, R.E., Brennan, M. & Fairweather, I. (2011a) Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabenda-zole in Fasciola hepatica. Veterinary Parasitology 176, 34-42.
15. Flanagan, A., Edgar, H.W.J., Gordon, A., Hanna, R.E.B., Brennan, G.P. & Fairweather, I. (2011b) Comparison of two assays, a faecal egg count reduction test (FECRT) and a coproantigen reduction test (CRT), for the diagnosis of resistance to triclabendazole in Fasciola hepatica in sheep. Veterinary Parasitology 176, 170-176.
16. Hanna, R.E., Edgar, H.W., McConnell, S., Toner, E., McConville, M., Brennan, G.P., Devine, C., Flanagan, A., Halferty, L., Meaney, M., Shaw, L., Moffett, D., McCoy, M. & Fairweather, I. (2010) Fasciola hepatica: histological changes in the reproductive structures of triclabendazole (TCBZ)-sensitive and TCBZ-resistant flukes after treatment in vivo with TCBZ and the related benzimidazole derivative, Compound Alpha. Veterinary Parasitology 168, 240-254.
17. Hanna, R.E.B., Forster, F.I., Brennan, G.P. & Fairweather, I. (2013) Fasciola hepatica: histological demonstration of apoptosis in the reproductive organs of flukes of triclabendazole-sensitive and triclabenda-zole-resistant isolates, and in field-derived flukes from triclabendazole-treated hosts, using in situ hybridization to visualize endonuclease-generated DNA strand breaks. Veterinary Parasitology 191, 240-251.
18. Hennessy, D., Steel, J., Lacey, E., Eagleson, G. & Prichard, R. (1989) The disposition of albendazole in sheep. Journal of Veterinary Pharmacology and Therapeutics 12, 421-429.
19. Lacey, E. (1990) Mode of action of benzimidazoles. Parasitology Today 6, 112-115.
20. Lanusse, C. & Prichard, R. (1993) Clinical pharmacoki-netics and metabolismofbenzimidazoles anthelmintics in ruminants. Drug Metabolism Reviews 25, 235-279.
21. Lubega, G. & Prichard, R. (1991) Interaction of benzimidazole anthelmintics with Haemonchus con-tortus tubulin: binding affinity and anthelmintic efficacy. Experimental Parasitology 73, 203-209.
22. Marriner, S. & Bogan, J. (1980) Pharmacokinetics of albendazole in sheep. American Journal of Veterinary Research 41, 1126-1129.
23. Mas-Coma, S., Bargues, M.D. & Valero, M.A. (2005) Fascioliasis and other plant-borne trematode zoo-noses. International Journal for Parasitology 35, 1255-1278.
24. McConville, M., Brennan, G.P., McCoy, M., Castillo, R., Hernández-Campos, A. & Fairweather, I. (2006) Adult triclabendazole-resistant Fasciola hepatica: surface and sub-surface tegumental responses to in vitro treatment with the sulphoxide metabolite of the experimental fasciolicide compound alpha. Parasitology 133, 195-208.
25. McConville, M., Brennan, G.P., Flanagan, A., Edgar, H.W., Hanna, R.E., McCoy, M., Gordon, A.W., Castillo, R., Hernández-Campos, A. & Fairweather, I. (2009) An evaluation of the efficacy of compound alpha and triclabendazole against two isolates of Fasciola hepatica. Veterinary Parasitology 162, 75-88.
26. McKellar, Q. & Scott, E. (1990) The benzimidazole anthelmintic agents-a review. Journal of Veterinary Pharmacology and Therapeutics 13, 223-247.
27. McKinstry, B., Halferty, L., Brennan, G.P. & Fairweather, I. (2009) Morphological response of triclabendazole-susceptible and triclabendazole resistant isolates of Fasciola hepatica to treatment in vitro with nitroxynil (Trodax). Parasitology Research 104, 645-655.
28. Moll, L., Gaasenbeek, C.P.H., Vellema, P. & Borgsteede, F.H. (2000) Resistance of Fasciola hepatica against triclabendazole in cattle and sheep in The Netherlands. Veterinary Parasitology 91, 153-158.
29. Olaechea, F., Lovera, V., Larroza, M., Raffo, F. & Cabrera, R. (2011a) Resistance of Fasciola hepatica against triclabendazole in cattle in Patagonia (Argentina). Veterinary Parasitology 178, 364-366.
30. rd International Conference of the World Association for the Advancement of Veterinary Parasitol-ogy, p. 85.
31. Ortiz, P., Cerna, C., Rosales, C., Cabrera, M., Solana, H., Scarcella, S., Lamenza, P. & Fernández, V. (2011) Eficacia del triclabendazol en el tratamiento de la infección natural por Fasciola hepatica en ganado vacuno lechero. Biomédica 31, 209-421.
32. Overend, D. & Bowen, F. (1995) Resistance of Fasciola hepatica to triclabendazole. Australian Veterinary Journal 72, 275-276.
33. Prichard, R., Hennessy, D., Steel, J. & Lacey, E. (1985) Metabolite concentrations in plasma following treatment of cattle with five anthelmintics. Research in Veterinary Science 39, 113-178.
34. Sanabria, R., Ceballos, L., Moreno, L., Romero, J., Lanusse, C. & Alvarez, L. (2013) Identification of a field isolate of Fasciola hepatica resistant to albendazole and susceptible to triclabendazole. Veterinary Parasitology 193, 105-110.
35. Thomas, I., Coles, G.C. & Duffus, K. (2000) Triclabenda-zole- resistant Fasciola hepatica in southwest Wales. Veterinary Record 12, 146-200.
36. Toner, E., Brennan, G.P., McConvery, F., Meaney, M. & Fairweather, I. (2010) A transmission electron microscope study on the route of entry of triclabendazole into the liver fluke, Fasciola hepatica. Parasitology 137, 855-870.
37. Walker, S.M., McKinstry, B., Boray, J.C., Brennan, G.P., Trudgett, A., Hoey, E.M., Fletcher, H. & Fairweather, I. (2004) Response of two isolates of Fasciola hepatica to treatment with triclabendazole in vivo and in vitro. Parasitology Research 94, 427-438.
38. Wood, I.B., Amaral, N.K., Bairden, K., Duncan, J.L., Kassai, T., Malone, J.B., Pankavich, J.A., Reinecke, R.K., Slocombe, O., Taylor, S.M. & Vercruysse, J.(1995) World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) second edition of guidelines for evaluatingthe efficacyofanthelminticsinruminants (bovine, ovine, caprine). Veterinary Parasitology 58, 181-213.