News feature: Next-generation antibiotics

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 31, 2014, Pages 11227-11229

  Williams, Sarah C P ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; DRUG INDUSTRY; GRAM NEGATIVE BACTERIUM; HUMAN; NONHUMAN; NOTE; PRIORITY JOURNAL; QUORUM SENSING; SCIENTIST;

ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MICROBIAL; HUMANS; IMMUNE SYSTEM; MICROBIAL SENSITIVITY TESTS; STAPHYLOCOCCUS AUREUS;

EID: 84905667072     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1413117111     Document Type: Note

References (7)

1. US Department of Health and Human Services (2013) Antibiotic Resistance Threats in the United States 2013. Centers for Disease Control and Prevention, Atlanta, GA.
2. Spellberg B (2013) New antibiotic development: Barriers and opportunities in 2012. Allliance Prudent Use Antibiotics Newsl 30(1):8-10.
3. O'Loughlin CT, et al. (2013) A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc Natl Acad Sci USA 110(44):17981-17986.
4. Kehl-Fie TE, et al. (2011) Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense, enhancing neutrophil killing of Staphylococcus aureus. Cell Host Microbe 10(2):158-164.
5. Damo SM, et al. (2013) Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens. Proc Natl Acad Sci USA 110(10):3841-3846.
6. Montor WR, et al. (2009) Genome-wide study of Pseudomonas aeruginosa outer membrane protein immunogenicity using self-assembling protein microarrays. Infect Immun 77(11):4877-4886.
7. Skurnik D, et al. (2013) A comprehensive analysis of in vitro and in vivo genetic fitness of Pseudomonas aeruginosa using high-throughput sequencing of transposon libraries. PLoS Pathog 9(9):e1003582.