Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis

Nature Structural and Molecular Biology

Volumn 21, Issue 8, 2014, Pages 696-703

  Park, Suk Youl ^a,b   Park, Jung Eun ^a   Kim, Tae Sung ^a   Kim, Ju Hee ^c   Kwak, Mi Jeong ^d   Ku, Bonsu ^c   Tian, Lan ^e   Murugan, Ravichandran N ^f   Ahn, Mija ^f   Komiya, Shinobu ^g   Hojo, Hironobu ^h   Kim, Nam Hyung ⁱ   Kim, Bo Yeon ^c   Bang, Jeong K ^f   Erikson, Raymond L ^j   Lee, Ki Won ^b,k   Kim, Seung Jun ^c   Oh, Byung Ha ^d   Yang, Wei ^e   Lee, Kyung S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Seoul National University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^d Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^e NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^f Korea Basic Science Institute (KBSI)   (South Korea)

^g TOKAI UNIVERSITY   (Japan)

^h OSAKA UNIVERSITY   (Japan)

ⁱ Chungbuk National University   (South Korea)

^j HARVARD UNIVERSITY   (United States)

^k Seoul National University   (South Korea)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; CELL CYCLE PROTEINS; CENTRIOLES; CHROMOSOMAL PROTEINS, NON-HISTONE; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HELA CELLS; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; NEOPLASMS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN-SERINE-THREONINE KINASES;

EID: 84905638127     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2846     Document Type: Article

References (41)

1. Gönczy, P. Towards a molecular architecture of centriole assembly. Nat. Rev. Mol. Cell Biol. 13, 425-435 (2012
2. Brito, D.A., Gouveia, S.M. & Bettencourt-Dias, M. Deconstructing the centriole: Structure and number control. Curr. Opin. Cell Biol. 24, 4-13 (2012
3. Nigg, E.A. & Stearns, T. The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries. Nat. Cell Biol. 13, 1154-1160 (2011
4. Ganem, N.J., Godinho, S.A. & Pellman, D. A mechanism linking extra centrosomes to chromosomal instability. Nature 460, 278-282 (2009
5. Holland, A.J. & Cleveland, D.W. Losing balance: The origin and impact of aneuploidy in cancer. EMBO Rep. 13, 501-514 (2012
6. Nigg, E.A. & Raff, J.W. Centrioles, centrosomes, and cilia in health and disease. Cell 139, 663-678 (2009
7. O'Connell, K.F. et al. The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo. Cell 105, 547-558 (2001
8. Bettencourt-Dias, M. et al. SAK/PLK4 is required for centriole duplication and flagella development. Curr. Biol. 15, 2199-2207 (2005
9. Habedanck, R., Stierhof, Y.D., Wilkinson, C.J. & Nigg, E.A. The Polo kinase Plk4 functions in centriole duplication. Nat. Cell Biol. 7, 1140-1146 (2005
10. Delattre, M., Canard, C. & Gönczy, P. Sequential protein recruitment in C. elegans centriole formation. Curr. Biol. 16, 1844-1849 (2006
11. Pelletier, L., O'Toole, E., Schwager, A., Hyman, A.A. & Müller-Reichert, T. Centriole assembly in Caenorhabditis elegans. Nature 444, 619-623 (2006
12. Dzhindzhev, N.S. et al. Asterless is a scaffold for the onset of centriole assembly. Nature 467, 714-718 (2010
13. Kim, T.-S. et al. Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152. Proc. Natl. Acad. Sci. USA 110, E4849-E4857 (2013
14. Sonnen, K.F., Gabryjonczyk, A.M., Anselm, E., Stierhof, Y.D. & Nigg, E.A. Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication. J. Cell Sci. 126, 3223-3233 (2013
15. Lawo, S., Hasegan, M., Gupta, G.D. & Pelletier, L. Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material. Nat. Cell Biol. 14, 1148-1158 (2012
16. Sonnen, K.F., Schermelleh, L., Leonhardt, H. & Nigg, E.A. 3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. Biol. Open 1, 965-976 (2012
17. Kitagawa, D. et al. Structural basis of the 9-fold symmetry of centrioles. Cell 144, 364-375 (2011
18. van Breugel, M. et al. Structures of SAS-6 suggest its organization in centrioles. Science 331, 1196-1199 (2011
19. Leung, G.C. et al. The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization. Nat. Struct. Biol. 9, 719-724 (2002
20. Slevin, L.K. et al. The structure of the plk4 cryptic polo box reveals two tandem polo boxes required for centriole duplication. Structure 20, 1905-1917 (2012
21. Elia, A.E. et al. The molecular basis for phospho-dependent substrate targeting and regulation of Plks by the polo-box domain. Cell 115, 83-95 (2003
22. Cizmecioglu, O. et al. Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome. J. Cell Biol. 191, 731-739 (2010
23. Hatch, E.M., Kulukian, A., Holland, A.J., Cleveland, D.W. & Stearns, T. Cep152 interacts with Plk4 and is required for centriole duplication. J. Cell Biol. 191, 721-729 (2010
24. Yun, S.M. et al. Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat. Struct. Mol. Biol. 16, 876-882 (2009
25. Ko, M.A. et al. Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis. Nat. Genet. 37, 883-888 (2005
26. Zhao, H. et al. The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis. Nat. Cell Biol. 15, 1434-1444 (2013
27. Dix, C.I. & Raff, J.W. Drosophila Spd-2 recruits PCM to the sperm centriole, but is dispensable for centriole duplication. Curr. Biol. 17, 1759-1764 (2007
28. Lin, Y.C. et al. Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly. EMBO J. 32, 1141-1154 (2013
29. Inanç, B. et al. Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells. Mol. Biol. Cell 24, 2645-2654 (2013
30. Kleylein-Sohn, J. et al. Plk4-induced centriole biogenesis in human cells. Dev. Cell 13, 190-202 (2007
31. Johmura, Y. et al. Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1. Proc. Natl. Acad. Sci. USA 108, 11446-11451 (2011
32. Lee, K.S., Yuan, Y.-L., Kuriyama, R. & Erikson, R.L. Plk is an M-phase-specific protein kinase and interacts with a kinesin-like protein, CHO1/MKLP-1. Mol. Cell. Biol. 15, 7143-7151 (1995
33. Sillibourne, J.E. et al. Autophosphorylation of polo-like kinase 4 and its role in centriole duplication. Mol. Biol. Cell 21, 547-561 (2010
34. Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326 (1997
35. McCoy, A.J. et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658-674 (2007
36. Emsley, P. & Cowtan, K. Coot: Model-building tools for molecular graphics. Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132 (2004
37. Adams, P.D. et al. PHENIX: A comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D Biol. Crystallogr. 66, 213-221 (2010
38. Brünger, A.T. et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 54, 905-921 (1998
39. Chen, V.B. et al. MolProbity: All-Atom structure validation for macromolecular crystallography. Acta Crystallogr. D Biol. Crystallogr. 66, 12-21 (2010
40. Kang, Y.H. et al. Mammalian polo-like kinase 1-dependent regulation of the PBIP1-CENP-Q complex at kinetochores. J. Biol. Chem. 286, 19744-19757 (2011
41. Liu, F. et al. Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel. Nat. Chem. Biol. 7, 595-601 (2011