Dysregulated extracellular signal-regulated kinase signaling associated with impaired B-cell receptor endocytosis in patients with common variable immunodeficiency

Journal of Allergy and Clinical Immunology

Volumn 134, Issue 2, 2014, Pages

  Visentini, Marcella ^a   Marrapodi, Ramona ^a   Conti, Valentina ^b   Mitrevski, Milica ^a   Camponeschi, Alessandro ^a   Lazzeri, Cristina ^a   Carbonari, Maurizio ^a   Catizone, Angela ^a   Quinti, Isabella ^b   Fiorilli, Massimo ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

B cell receptor; Common variable immunodeficiency; endocytosis; extracellular signal regulated kinase

Indexed keywords

B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 21; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE; COMPLEMENT COMPONENT C3D RECEPTOR; IMMUNOGLOBULIN; LAMP1 PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN;

ADULT; AGED; ARTICLE; B LYMPHOCYTE; CELL MIGRATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; COMMON VARIABLE IMMUNODEFICIENCY; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CROSS LINKING; ENDOCYTOSIS; ENDOSOME; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IN VITRO STUDY; INTERNALIZATION; MALE; MEMORY CELL; MIDDLE AGED; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; CASE CONTROL STUDY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN TRANSPORT; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; B-LYMPHOCYTE SUBSETS; CASE-CONTROL STUDIES; COMMON VARIABLE IMMUNODEFICIENCY; ENDOCYTOSIS; ENDOSOMES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOGLOBULIN M; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC MEMORY; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MALE; MIDDLE AGED; PHOSPHORYLATION; PROTEIN TRANSPORT; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, COMPLEMENT 3D; SIGNAL TRANSDUCTION;

EID: 84905591094     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.03.017     Document Type: Article

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