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Volumn 134, Issue 2, 2014, Pages 262-266

A phase II study of gemcitabine, carboplatin and bevacizumab for the treatment of platinum-sensitive recurrent ovarian cancer

Author keywords

Bevacizumab; Chemotherapy; Gemcitabine; Ovarian cancer; Platinum sensitive; Recurrent

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CISPLATIN; GEMCITABINE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

EID: 84905590135     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2014.05.030     Document Type: Article
Times cited : (17)

References (24)
  • 2
    • 19744368302 scopus 로고    scopus 로고
    • Cancer of the ovary
    • S.A. Cannistra Cancer of the ovary N Engl J Med 351 2004 2519 2529
    • (2004) N Engl J Med , vol.351 , pp. 2519-2529
    • Cannistra, S.A.1
  • 3
    • 0037862963 scopus 로고    scopus 로고
    • Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: The ICON4/AGO-OVAR-2.2 trial
    • M.K. Parmar, J.A. Ledermann, N. Colombo, A. du Bois, J.F. Delaloye, and G.B. Kristensen et al. Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial Lancet 361 2003 2099 2106
    • (2003) Lancet , vol.361 , pp. 2099-2106
    • Parmar, M.K.1    Ledermann, J.A.2    Colombo, N.3    Du Bois, A.4    Delaloye, J.F.5    Kristensen, G.B.6
  • 4
    • 33750588670 scopus 로고    scopus 로고
    • Gemcitabine plus carboplatin compared with carboplatin in patients with platinum-sensitive recurrent ovarian cancer: An intergroup trial of the AGO-OVAR, the NCIC CTG, and the EORTC GCG
    • J. Pfisterer, M. Plante, I. Vergote, A. du Bois, H. Hirte, and A.J. Lacave et al. Gemcitabine plus carboplatin compared with carboplatin in patients with platinum-sensitive recurrent ovarian cancer: an intergroup trial of the AGO-OVAR, the NCIC CTG, and the EORTC GCG J Clin Oncol 24 2006 4699 4707
    • (2006) J Clin Oncol , vol.24 , pp. 4699-4707
    • Pfisterer, J.1    Plante, M.2    Vergote, I.3    Du Bois, A.4    Hirte, H.5    Lacave, A.J.6
  • 5
    • 77954726606 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin and carboplatin compared with paclitaxel and carboplatin for patients with platinum-sensitive ovarian cancer in late relapse
    • E. Pujade-Lauraine, U. Wagner, E. Aavall-Lundqvist, V. Gebski, M. Heywood, and P.A. Vasey et al. Pegylated liposomal doxorubicin and carboplatin compared with paclitaxel and carboplatin for patients with platinum-sensitive ovarian cancer in late relapse J Clin Oncol 28 2010 3323 3329
    • (2010) J Clin Oncol , vol.28 , pp. 3323-3329
    • Pujade-Lauraine, E.1    Wagner, U.2    Aavall-Lundqvist, E.3    Gebski, V.4    Heywood, M.5    Vasey, P.A.6
  • 7
    • 0037224987 scopus 로고    scopus 로고
    • Gemcitabine reverses cisplatin resistance: Demonstration of activity in platinum- and multidrug-resistant ovarian and peritoneal carcinoma
    • G. Rose, K. Mossbruger, N. Fusco, M. Smrekar, S. Eaton, and M. Rodriguez Gemcitabine reverses cisplatin resistance: demonstration of activity in platinum- and multidrug-resistant ovarian and peritoneal carcinoma Gynecol Oncol 88 2003 17 21
    • (2003) Gynecol Oncol , vol.88 , pp. 17-21
    • Rose, G.1    Mossbruger, K.2    Fusco, N.3    Smrekar, M.4    Eaton, S.5    Rodriguez, M.6
  • 8
    • 0037229630 scopus 로고    scopus 로고
    • Phase II trial of gemcitabine plus cisplatin repeating doublet therapy in previously treated, relapsed ovarian cancer patients
    • R.A. Nagourney, C.A. Brewer, S. Radecki, W.A. Kidder, B.L. Sommers, and S.S. Evans et al. Phase II trial of gemcitabine plus cisplatin repeating doublet therapy in previously treated, relapsed ovarian cancer patients Gynecol Oncol 88 2003 35 39
    • (2003) Gynecol Oncol , vol.88 , pp. 35-39
    • Nagourney, R.A.1    Brewer, C.A.2    Radecki, S.3    Kidder, W.A.4    Sommers, B.L.5    Evans, S.S.6
  • 9
    • 0024549349 scopus 로고
    • Induction of angiogenesis during the transition from hyperplasia to neoplasia
    • J. Folkman, K. Watson, D. Ingber, and D. Hanahan Induction of angiogenesis during the transition from hyperplasia to neoplasia Nature 339 1989 58 61
    • (1989) Nature , vol.339 , pp. 58-61
    • Folkman, J.1    Watson, K.2    Ingber, D.3    Hanahan, D.4
  • 10
    • 33745738260 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: From the biology to the clinic
    • G. Ranieri, R. Patruno, E. Ruggieri, S. Montemurro, P. Valerio, and D. Ribatti Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic Curr Med Chem 13 2006 1845 1857
    • (2006) Curr Med Chem , vol.13 , pp. 1845-1857
    • Ranieri, G.1    Patruno, R.2    Ruggieri, E.3    Montemurro, S.4    Valerio, P.5    Ribatti, D.6
  • 11
    • 36849056497 scopus 로고    scopus 로고
    • Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer
    • S.A. Cannistra, U.A. Matulonis, R.T. Penson, J. Hambleton, J. Dupont, and H. Mackey et al. Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer J Clin Oncol 25 2007 5180 5186
    • (2007) J Clin Oncol , vol.25 , pp. 5180-5186
    • Cannistra, S.A.1    Matulonis, U.A.2    Penson, R.T.3    Hambleton, J.4    Dupont, J.5    MacKey, H.6
  • 12
    • 36849019301 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group Study
    • R.A. Burger, M.W. Sill, B.J. Monk, B.E. Greer, and J.L. Sorosky Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study J Clin Oncol 25 2007 5165 5171
    • (2007) J Clin Oncol , vol.25 , pp. 5165-5171
    • Burger, R.A.1    Sill, M.W.2    Monk, B.J.3    Greer, B.E.4    Sorosky, J.L.5
  • 13
    • 37849035249 scopus 로고    scopus 로고
    • Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A trial of the California, Chicago, and Princess Margaret Hospital phase II consortia
    • A.A. Garcia, H. Hirte, G. Fleming, D. Yang, D.D. Tsao-Wei, and L. Roman et al. Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia J Clin Oncol 26 2008 76 82
    • (2008) J Clin Oncol , vol.26 , pp. 76-82
    • Garcia, A.A.1    Hirte, H.2    Fleming, G.3    Yang, D.4    Tsao-Wei, D.D.5    Roman, L.6
  • 14
    • 33749135305 scopus 로고    scopus 로고
    • Gemcitabine (GEM) + oxaliplatin (OX) in patients with stage III/IV ovarian cancer following 3 cycles of carboplatin (CB) + paclitaxel (PAC): Preliminary report of a phase II study
    • ASCO Annual Meeting
    • R.I.J. Arca, G. Lerzo, M. Mandachain, E. Mickievicz, and J. Perez et al. Gemcitabine (GEM) + oxaliplatin (OX) in patients with stage III/IV ovarian cancer following 3 cycles of carboplatin (CB) + paclitaxel (PAC): preliminary report of a phase II study ASCO Annual Meeting J Clin Oncol 22 2004 5111
    • (2004) J Clin Oncol 22 , pp. 5111
    • Arca, R.I.J.1    Lerzo, G.2    Mandachain, M.3    Mickievicz, E.4    Perez, J.5
  • 15
    • 33749148870 scopus 로고    scopus 로고
    • Biweekly oxaliplatin (oxa) and gemcitabine (gem) in cisplatinum pretreated patients with relapsed ovarian cancer (roc): Preliminary data of a phase II trial
    • ASCO Annual Meeting Abstract
    • D. Germano, D. Bilancia, A. Di Nota, A.M. Dello Russo, R. Romano, and G. Rosati et al. Biweekly oxaliplatin (oxa) and gemcitabine (gem) in cisplatinum pretreated patients with relapsed ovarian cancer (roc): preliminary data of a phase II trial ASCO Annual Meeting Abstract J Clin Oncol 22 2004 5104
    • (2004) J Clin Oncol 22 , pp. 5104
    • Germano, D.1    Bilancia, D.2    Di Nota, A.3    Dello Russo, A.M.4    Romano, R.5    Rosati, G.6
  • 16
    • 1242338157 scopus 로고    scopus 로고
    • Concurrent chemoradiotherapy with gemcitabine and cisplatin after incomplete (R1) resection of locally advanced pancreatic carcinoma
    • R. Wilkowski, M. Thoma, E. Dühmke, H.G. Rau, and V. Heinemann Concurrent chemoradiotherapy with gemcitabine and cisplatin after incomplete (R1) resection of locally advanced pancreatic carcinoma Int J Radiat Oncol Biol Phys 58 2004 768 772
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 768-772
    • Wilkowski, R.1    Thoma, M.2    Dühmke, E.3    Rau, H.G.4    Heinemann, V.5
  • 17
    • 84861736119 scopus 로고    scopus 로고
    • OCEANS: A randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer
    • C. Aghajanian, S.V. Blank, B.A. Goff, P.L. Judson, M.G. Teneriello, and A. Husain et al. OCEANS: a randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer J Clin Oncol 30 2012 2039 2045
    • (2012) J Clin Oncol , vol.30 , pp. 2039-2045
    • Aghajanian, C.1    Blank, S.V.2    Goff, B.A.3    Judson, P.L.4    Teneriello, M.G.5    Husain, A.6
  • 18
    • 80051913984 scopus 로고    scopus 로고
    • 2010 Gynecologic Cancer InterGroup (GCIG) consensus statement on clinical trials in ovarian cancer: Report from the Fourth Ovarian Cancer Consensus Conference
    • G.C. Stuart, H. Kitchener, M. Bacon, A. du Bois, M. Friedlander, and J. Ledermann et al. 2010 Gynecologic Cancer InterGroup (GCIG) consensus statement on clinical trials in ovarian cancer: report from the Fourth Ovarian Cancer Consensus Conference Int J Gynecol Cancer 21 2011 750 755
    • (2011) Int J Gynecol Cancer , vol.21 , pp. 750-755
    • Stuart, G.C.1    Kitchener, H.2    Bacon, M.3    Du Bois, A.4    Friedlander, M.5    Ledermann, J.6
  • 19
    • 0032958512 scopus 로고    scopus 로고
    • Mechanisms of synergism between cisplatin and gemcitabine in ovarian and non-small-cell lung cancer cell lines
    • C.J. van Moorsel, H.M. Pinedo, G. Veerman, A.M. Bergman, C.M. Kuiper, and J.B. Vermorken et al. Mechanisms of synergism between cisplatin and gemcitabine in ovarian and non-small-cell lung cancer cell lines Br J Cancer 80 1999 981 990
    • (1999) Br J Cancer , vol.80 , pp. 981-990
    • Van Moorsel, C.J.1    Pinedo, H.M.2    Veerman, G.3    Bergman, A.M.4    Kuiper, C.M.5    Vermorken, J.B.6
  • 20
    • 10244252761 scopus 로고    scopus 로고
    • Gemcitabine and cisplatin chemotherapy is an active combination in the treatment of platinum-resistant ovarian and peritoneal carcinoma
    • D. Tewari, B.J. Monk, M. Hunter, C.A. Falkner, and R.A. Burger Gemcitabine and cisplatin chemotherapy is an active combination in the treatment of platinum-resistant ovarian and peritoneal carcinoma Invest New Drugs 22 2004 475 480
    • (2004) Invest New Drugs , vol.22 , pp. 475-480
    • Tewari, D.1    Monk, B.J.2    Hunter, M.3    Falkner, C.A.4    Burger, R.A.5
  • 21
    • 33746288695 scopus 로고    scopus 로고
    • Cisplatin plus gemcitabine in platinum-refractory ovarian or primary peritoneal cancer: A phase II study of the Gynecologic Oncology Group
    • C.A. Brewer, J.A. Blessing, R.A. Nagourney, M. Morgan, and P. Hanjani Cisplatin plus gemcitabine in platinum-refractory ovarian or primary peritoneal cancer: a phase II study of the Gynecologic Oncology Group Gynecol Oncol 103 2006 446 450
    • (2006) Gynecol Oncol , vol.103 , pp. 446-450
    • Brewer, C.A.1    Blessing, J.A.2    Nagourney, R.A.3    Morgan, M.4    Hanjani, P.5
  • 22
    • 33846990923 scopus 로고    scopus 로고
    • Biweekly gemcitabine and cisplatin in platinum-resistant/refractory, paclitaxel-pretreated, ovarian and peritoneal carcinoma
    • G. Bozas, A. Bamias, V. Koutsoukou, E. Efstathiou, D. Gika, and C.A. Papadimitriou et al. Biweekly gemcitabine and cisplatin in platinum-resistant/ refractory, paclitaxel-pretreated, ovarian and peritoneal carcinoma Gynecol Oncol 104 2007 580 585
    • (2007) Gynecol Oncol , vol.104 , pp. 580-585
    • Bozas, G.1    Bamias, A.2    Koutsoukou, V.3    Efstathiou, E.4    Gika, D.5    Papadimitriou, C.A.6
  • 23
    • 77957564535 scopus 로고    scopus 로고
    • Inhibition of carboplatin-induced DNA interstrand cross-link repair by gemcitabine in patients receiving these drugs for platinum-resistant ovarian cancer
    • J.A. Ledermann, H. Gabra, G.C. Jayson, V.J. Spanswick, G.J. Rustin, and M. Jitlal et al. Inhibition of carboplatin-induced DNA interstrand cross-link repair by gemcitabine in patients receiving these drugs for platinum-resistant ovarian cancer Clin Cancer Res 16 2010 4899 4905
    • (2010) Clin Cancer Res , vol.16 , pp. 4899-4905
    • Ledermann, J.A.1    Gabra, H.2    Jayson, G.C.3    Spanswick, V.J.4    Rustin, G.J.5    Jitlal, M.6
  • 24
    • 70350569388 scopus 로고    scopus 로고
    • Fixed-dose rate gemcitabine plus carboplatin in relapsed, platinum-sensitive ovarian cancer patients: Results of a three-arm Phase i study
    • R.D. Alvarez, R. Mannel, A.A. Garcia, H.H. Gallion, J. Lucci 3rd, and L.C. Kilgore et al. Fixed-dose rate gemcitabine plus carboplatin in relapsed, platinum-sensitive ovarian cancer patients: results of a three-arm Phase I study Gynecol Oncol 115 2009 389 395
    • (2009) Gynecol Oncol , vol.115 , pp. 389-395
    • Alvarez, R.D.1    Mannel, R.2    Garcia, A.A.3    Gallion, H.H.4    Lucci III, J.5    Kilgore, L.C.6


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