Defining HNPCC and Lynch syndrome: What's in a name?

Gut

Volumn 63, Issue 9, 2014, Pages 1525-1526

  Kravochuck, S E ^a   Kalady, M F ^a   Burke, C A ^a   Heald, B ^a   Church, J M ^a  

^a Sanford R Weiss MD Center for Hereditary Colorectal Neoplasia   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLORECTAL CANCER GENES; COLORECTAL NEOPLASIA;

BIBLIOMETRICS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DIAGNOSIS, DIFFERENTIAL; HUMANS; PRACTICE GUIDELINES AS TOPIC; TERMINOLOGY AS TOPIC;

EID: 84905570542     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2014-307344     Document Type: Note

References (8)

1. Vasen HF, Blanco I, Aktan-Collan K, et al. Mallorca group revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts. Gut 2013;62:812-23.
2. Jass J. Hereditary non-polyposis colorectal cancer: the rise and fall of a confusing term. World J Gastroenterol 2006;12:4943-50. (Pubitemid 44323261)
3. Evaluation of Genomic Applications in Practice and Prevention Working Group. Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives. Genet Med 2009;11:35-41.
4. Ribic CM, Sargent DJ, Moore MJ, et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 2003;349:247-57. (Pubitemid 36859476)
5. Kalady M, Kravochuck S, Church J. Reconsidering the "non" in hereditary nonpolyposis colorectal cancer; multiple adenomas do not preclude Lynch Syndrome. Dis Colon Rectum 2013;56:e65-e313.
6. Rodríguez-Soler M, Pérez-Carbonell L, Guarinos C, et al. Risk of cancer in cases of suspected lynch syndrome without germline mutation. Gastroenterology 2013;144:926-32.
7. Sourrouille I, Coulet F, Lefevre JH, et al. Somatic mosaicism and double somatic hits can lead to MSI colorectal tumors. Fam Cancer 2013;12:27-33.
8. 2 are a frequent cause of mismatch-repair deficiency in Lynch syndrome-like tumors. Gastroenterology 2014;146:643-6.