Coronary Microvascular Dysfunction Is Related to Abnormalities in Myocardial Structure and Function in Cardiac Amyloidosis

JACC: Heart Failure

Volumn 2, Issue 4, 2014, Pages 358-367

  Dorbala, Sharmila ^a   Vangala, Divya ^a   Bruyere, John ^a   Quarta, Christina ^a   Kruger, Jenna ^a   Padera, Robert ^a   Foster, Courtney ^a   Hanley, Michael ^a   Di Carli, Marcelo F ^a   Falk, Rodney ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Amyloidosis; Coronary microvascular function; Myocardial blood flow; PET; Strain

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE; AMMONIA N 13; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIPYRIDAMOLE; DIURETIC AGENT; HYPOCHOLESTEROLEMIC AGENT; REGADENOSON;

ADULT; AGE; ARTICLE; BODY MASS; CARDIOVASCULAR FUNCTION; CLINICAL ARTICLE; COMORBIDITY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY FLOW RESERVE; CORONARY MICROVASCULAR DYSFUNCTION; CORONARY VASCULAR RESISTANCE; DISEASE ASSOCIATION; ELECTROCARDIOGRAM; FEMALE; HEART AMYLOIDOSIS; HEART FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART MUSCLE; HEART MUSCLE BLOOD FLOW; HEART MUSCLE PERFUSION; HUMAN; HYPEREMIA; MALE; MEDICAL HISTORY; OUTCOME ASSESSMENT; POSITRON EMISSION TOMOGRAPHY; PREDICTOR VARIABLE; PREVALENCE; PRIORITY JOURNAL; SYMPTOMATOLOGY; TWO DIMENSIONAL ECHOCARDIOGRAPHY; VASCULAR DISEASE; ADRENERGIC SYSTEM; AMYLOIDOSIS; BLOOD FLOW VELOCITY; CARDIOMYOPATHY; COMPUTER ASSISTED TOMOGRAPHY; CORONARY ARTERY BLOOD FLOW; CORONARY BLOOD VESSEL; ELECTROCARDIOGRAPHY; HEART LEFT VENTRICLE FUNCTION; MICROVASCULATURE; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROSPECTIVE STUDY;

AMYLOIDOSIS; BLOOD FLOW VELOCITY; CARDIOMYOPATHIES; CORONARY CIRCULATION; CORONARY VESSELS; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; HYPEREMIA; HYPERTROPHY, LEFT VENTRICULAR; MALE; MICROVESSELS; MIDDLE AGED; MYOCARDIUM; POSITRON-EMISSION TOMOGRAPHY; PROSPECTIVE STUDIES; TOMOGRAPHY, X-RAY COMPUTED; VASOMOTOR SYSTEM; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84905499600     PISSN: 22131779     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchf.2014.03.009     Document Type: Article

References (22)

1. Westermark P., Benson M.D., Buxbaum J.N., et al. Amyloid: toward terminology clarification. Report from the Nomenclature Committee of the International Society of Amyloidosis. Amyloid 2005, 12:1-4.
2. Sharma P.P., Payvar S., Litovsky S.H. Histomorphometric analysis of intramyocardial vessels in primary and senile amyloidosis: epicardium versus endocardium. Cardiovasc Pathol 2008, 17:65-71.
3. Tsai S.B., Seldin D.C., Wu H., O'Hara C., Ruberg F.L., Sanchorawala V. Myocardial infarction with "clean coronaries" caused by amyloid light-chain AL amyloidosis: a case report and literature review. Amyloid 2011, 18:160-164.
4. Al Suwaidi J., Velianou J.L., Gertz M.A., et al. Systemic amyloidosis presenting with angina pectoris. Ann Intern Med 1999, 131:838-841.
5. Ogawa H., Mizuno Y., Ohkawara S., et al. Cardiac amyloidosis presenting as microvascular angina-a case report. Angiology 2001, 52:273-278.
6. Whitaker D.C., Tungekar M.F., Dussek J.E. Angina with a normal coronary angiogram caused by amyloidosis. Heart 2004, 90:e54.
7. Buja L.M., Khoi N.B., Roberts W.C. Clinically significant cardiac amyloidosis. Clinicopathologic findings in 15 patients. Am J Cardiol 1970, 26:394-405.
8. Modesto K.M., Dispenzieri A., Gertz M., et al. Vascular abnormalities in primary amyloidosis. Eur Heart J 2007, 28:1019-1024.
9. Hongo M., Yamamoto H., Kohda T., et al. Comparison of electrocardiographic findings in patients with AL (primary) amyloidosis and in familial amyloid polyneuropathy and anginal pain and their relation to histopathologic findings. Am J Cardiol 2000, 85:849-853.
10. Smith R.R., Hutchins G.M. Ischemic heart disease secondary to amyloidosis of intramyocardial arteries. Am J Cardiol 1979, 44:413-417.
11. Dorbala S., Vangala D., Sampson U., Limaye A., Kwong R., Di Carli M.F. Value of vasodilator left ventricular ejection fraction reserve in evaluating the magnitude of myocardium at risk and the extent of angiographic coronary artery disease: a 82Rb PET/CT study. J Nucl Med 2007, 48:349-358.
12. DeGrado T.R., Hanson M.W., Turkington T.G., et al. Estimation of myocardial blood flow for longitudinal studies with 13N-labeled ammonia and positron emission tomography. J Nucl Cardiol 1996, 3:494-507.
13. Koyama J., Falk R.H. Prognostic significance of strain Doppler imaging in light-chain amyloidosis. J Am Coll Cardiol Cardiovasc Img 2010, 3:333-342.
14. Bernardi L., Passino C., Porta C., Anesi E., Palladini G., Merlini G. Widespread cardiovascular autonomic dysfunction in primary amyloidosis: does spontaneous hyperventilation have a compensatory role against postural hypotension?. Heart 2002, 88:615-621.
15. Vinik A.I., Ziegler D. Diabetic cardiovascular autonomic neuropathy. Circulation 2007, 115:387-397.
16. Di Carli M.F., Bianco-Batlles D., Landa M.E., et al. Effects of autonomic neuropathy on coronary blood flow in patients with diabetes mellitus. Circulation 1999, 100:813-819.
17. Stevens M.J., Dayanikli F., Raffel D.M., et al. Scintigraphic assessment of regionalized defects in myocardial sympathetic innervation and blood flow regulation in diabetic patients with autonomic neuropathy. J Am Coll Cardiol 1998, 31:1575-1584.
18. Camici P.G., Crea F. Coronary microvascular dysfunction. N Engl J Med 2007, 356:830-840.
19. Kofflard M.J., Michels M., Krams R., et al. Coronary flow reserve in hypertrophic cardiomyopathy: relation with microvascular dysfunction and pathophysiological characteristics. Neth Heart J 2007, 15:209-215.
20. Elliott P.M., Kindler H., Shah J.S., et al. Coronary microvascular dysfunction in male patients with Anderson-Fabry disease and the effect of treatment with alpha galactosidase A. Heart 2006, 92:357-360.
21. Neglia D., Parodi O., Gallopin M., et al. Myocardial blood flow response to pacing tachycardia and to dipyridamole infusion in patients with dilated cardiomyopathy without overt heart failure. A quantitative assessment by positron emission tomography. Circulation 1995, 92:796-804.
22. Tomberli B., Cecchi F., Sciagra R., et al. Coronary microvascular dysfunction is an early feature of cardiac involvement in patients with Anderson-Fabry disease. Eur J Heart Fail 2013, 15:1363-1373.