Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate

Acta Crystallographica Section F:Structural Biology Communications

Volumn 70, Issue 3, 2014, Pages 299-304

  Park, Jaeok ^a   Lin, Yih Shyan ^a   Tsantrizos, Youla S ^a   Berghuis, Albert M ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

anomalous diffraction; bisphosphonates; farnesyl pyrophosphate synthase; inorganic phosphate

Indexed keywords

AMINOPYRIDINE DERIVATIVE; BISPHOSPHONIC ACID DERIVATIVE; FARNESYL PYROPHOSPHATE SYNTHASE; GERANYLTRANSFERASE; PHOSPHATE;

AMINO ACID SEQUENCE; ANOMALOUS DIFFRACTION; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; HUMAN; MOLECULAR GENETICS; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY;

ANOMALOUS DIFFRACTION; BISPHOSPHONATES; FARNESYL PYROPHOSPHATE SYNTHASE; INORGANIC PHOSPHATE;

AMINO ACID SEQUENCE; AMINOPYRIDINES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIPHOSPHONATES; GERANYLTRANSTRANSFERASE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHATES; PROTEIN BINDING;

EID: 84905497049     PISSN: None     EISSN: 2053230X     Source Type: Journal    
DOI: 10.1107/S2053230X14002106     Document Type: Article

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