Chemo-immunotherapeutic antimalarials targeting isoprenoid biosynthesis

ACS Medicinal Chemistry Letters

Volumn 4, Issue 4, 2013, Pages 423-427

  Zhang, Yonghui ^a,b   Zhu, Wei ^c   Liu, Yi Liang ^c   Wang, Hong ^d   Wang, Ke ^b   Li, Kai ^b   No, Joo Hwan ^e   Ayong, Lawrence ^e   Gulati, Anmol ^b   Pang, Ran ^c   Freitas Junior, Lucio ^e   Morita, Craig T ^d   Oldfield, Eric ^b,c  

^a PrenylX Research Institute   (China)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d UNIVERSITY OF IOWA   (United States)

^e Institute Pasteur Korea   (South Korea)

Author keywords

Bisphosphonates; immunology; inhibitors; malaria

Indexed keywords

ANTIMALARIAL AGENT; FARNESYL TRANS TRANSFERASE; GERANYLTRANSFERASE; ISOPRENOID;

ANTIMALARIAL ACTIVITY; ARTICLE; CRYSTAL STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; INNATE IMMUNITY; MEMBRANE PERMEABILITY; NONHUMAN; PLASMODIUM; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 84876265215     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml4000436     Document Type: Article

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