Photodynamic therapy during supportive periodontal care: Clinical, microbiologic, immunoinflammatory, and patient-centered performance in a split-mouth randomized clinical trial

Journal of Periodontology

Volumn 85, Issue 8, 2014, Pages

  Kolbe, Maria F ^a   Ribeiro, Fernanda V ^a   Luchesi, Vanessa H ^a   Casarin, Renato C ^a   Sallum, Enilson A ^b   Nociti, Francisco H ^b   Ambrosano, Gláucia M B ^b   Cirano, Fabiano R ^a   Pimentel, Suzana P ^a   Casati, Marcio Z ^a  

^a PAULISTA UNIVERSITY   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Chronic periodontitis; Cytokines; Microbiology; Pain; Periodontal pocket; Photochemotherapy

Indexed keywords

CYTOKINE; GAMMA INTERFERON; IL4 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; PHOTOSENSITIZING AGENT;

ADULT; AGED; AGGREGATIBACTER ACTINOMYCETEMCOMITANS; BACTERIAL LOAD; CHRONIC PERIODONTITIS; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECTS; FEMALE; FOLLOW UP; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; MIDDLE AGED; PATIENT SATISFACTION; PERIODONTAL POCKET; PERIODONTICS; PHOTOCHEMOTHERAPY; PORPHYROMONAS GINGIVALIS; PREVENTIVE DENTISTRY; PROCEDURES; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; TREATMENT OUTCOME;

ADULT; AGED; AGGREGATIBACTER ACTINOMYCETEMCOMITANS; BACTERIAL LOAD; CHRONIC PERIODONTITIS; CYTOKINES; DENTAL SCALING; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; INTERLEUKIN-4; INTERLEUKIN-6; MALE; MIDDLE AGED; PATIENT SATISFACTION; PERIODONTAL INDEX; PERIODONTAL POCKET; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYROMONAS GINGIVALIS; PROSPECTIVE STUDIES; ROOT PLANING; SINGLE-BLIND METHOD; TREATMENT OUTCOME;

EID: 84905494884     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2014.130559     Document Type: Article

References (50)

1. Matuliene G, Pjetursson BE, Salvi GE, et al. Influence of residual pockets on progression of periodontitis and tooth loss: Results after 11 years of maintenance. J Clin Periodontol 2008;35:685-695.
2. Lorentz TC, Cota LO, Cortelli JR, Vargas AM, Costa FO. Prospective study of complier individuals under periodontal maintenance therapy: Analysis of clinical periodontal parameters, risk predictors and the progression of periodontitis. J Clin Periodontol 2009;36:58-67.
3. Anderson GB, Palmer JA, Bye FL, Smith BA, Caffesse RG. Effectiveness of subgingival scaling and root planing: Single versus multiple episodes of instrumentation. J Periodontol 1996;67:367-373.
4. Jenkins WM, Said SH, Radvar M, Kinane DF. Effect of subgingival scaling during supportive therapy. J Clin Periodontol 2000;27:590-596.
5. Serino G, Rosling B, Ramberg P, Hellström MK, Socransky SS, Lindhe J. The effect of systemic antibiotics in the treatment of patients with recurrent periodontitis. J Clin Periodontol 2001;28:411-418.
6. Eickholz P, Kim TS, Schacher B, Reitmeir P, Bürklin T, Ratka-Krüger P. Subgingival topical doxycycline versus mechanical debridement for supportive periodontal therapy: A single blind randomized controlled two-center study. Am J Dent 2005;18:341-346.
7. Leung WK, Jin L, Yau JY, Sun Q, Corbet EF. Microflora cultivable from minocycline strips placed in persisting periodontal pockets. Arch Oral Biol 2005;50:39-48.
8. McColl E, Patel K, Dahlen G, et al. Supportive periodontal therapy using mechanical instrumentation or 2% minocycline gel: A 12 month randomized, controlled, single masked pilot study. J Clin Periodontol 2006;33:141-150.
9. König J, Schwahn C, Fanghänel J, Plötz J, Hoffmann T, Kocher T. Repeated scaling versus surgery in young adults with generalized advanced periodontitis. J Periodontol 2008;79:1006-1013.
10. Preus HR, Lassen J, Aass AM, Ciancio SG. Bacterial resistance following subgingival and systemic administration of minocycline. J Clin Periodontol 1995;22:380-384.
11. Chan Y, Lai CH. Bactericidal effects of different laser wavelengths on periodontopathic germs in photodynamic therapy. Lasers Med Sci 2003;18:51-55.
12. Ge L, Shu R, Li Y, et al. Adjunctive effect of photodynamic therapy to scaling and root planing in the treatment of chronic periodontitis. Photomed Laser Surg 2011;29:33-37.
13. Theodoro LH, Silva SP, Pires JR, et al. Clinical and microbiological effects of photodynamic therapy associated with nonsurgical periodontal treatment. A 6-month follow-up. Lasers Med Sci 2012;27:687-693.
14. Luchesi VH, Pimentel SP, Kolbe MF, et al. Photodynamic therapy in the treatment of class II furcation: A randomized controlled clinical trial. J Clin Periodontol 2013;40:781-788.
15. Chondros P, Nikolidakis D, Christodoulides N, Rössler R, Gutknecht N, Sculean A. Photodynamic therapy as adjunct to non-surgical periodontal treatment in patients on periodontal maintenance: A randomized controlled clinical trial. Lasers Med Sci 2009;24:681-688.
16. Campos GN, Pimentel SP, Ribeiro FV, et al. The adjunctive effect of photodynamic therapy for residual pockets in single-rooted teeth: A randomized controlled clinical trial. Lasers Med Sci 2013;28:317-324.
17. Rühling A, Fanghänel J, Houshmand M, et al. Photodynamic therapy of persistent pockets in maintenance patients - A clinical study. Clin Oral Investig 2010;14:637-644.
18. Cappuyns I, Cionca N, Wick P, Giannopoulou C, Mombelli A. Treatment of residual pockets with photodynamic therapy, diode laser, or deep scaling. A randomized, split-mouth controlled clinical trial. Lasers Med Sci 2012;27:979-986.
19. Braun A, Krause F, Nolden R, Frentzen M. Subjective intensity of pain during the treatment of periodontal lesions with the Vector-system. J Periodontal Res 2003;38:135-140.
20. Hujoel PP. Endpoints in periodontal trials: The need for an evidence-based research approach. Periodontol 2000 2004;36:196-204.
21. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1-6.
22. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J 1975;25:229-235.
23. Mühlemann HR, Son S. Gingival sulcus bleeding - A leading symptom in initial gingivitis. Helv Odontol Acta 1971;15:107-113.
24. Casarin RC, Ribeiro Edel P, Mariano FS, Nociti FH Jr., Casati MZ, Goncxalves RB. Levels of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, inflammatory cytokines and species-specific immunoglobulin G in generalized aggressive and chronic periodontitis. J Periodontal Res 2010;45:635-642.
25. Ribeiro FV, Casarin RC, Palma MA, Júnior FH, Sallum EA, Casati MZ. Clinical and patient-centered outcomes after minimally invasive non-surgical or surgical approaches for the treatment of intrabony defects: A randomized clinical trial. J Periodontol 2011;82:1256-1266.
26. Wilson M, Gibson M, Strahan D, Harvey W. A preliminary evaluation of the use of a redox agent in the treatment of chronic periodontitis. J Periodontal Res 1992;27:522-527.
27. Dörtbudak O, Haas R, Bernhart T, Mailath-Pokorny G. Lethal photosensitization for decontamination of implant surfaces in the treatment of peri-implantitis. Clin Oral Implants Res 2001;12:104-108.
28. Usacheva MN, Teichert MC, Biel MA. The role of the methylene blue and toluidine blue monomers and dimers in the photoinactivation of bacteria. J Photochem Photobiol B 2003;71:87-98.
29. Lang NP, Adler R, Joss A, Nyman S. Absence of bleeding on probing. An indicator of periodontal stability. J Clin Periodontol 1990;17:714-721.
30. Woodruff LD, Bounkeo JM, Brannon WM, et al. The efficacy of laser therapy in wound repair: A metaanalysis of the literature. Photomed Laser Surg 2004;22:241-247.
31. De Oliveira RR, Schwartz-Filho HO, Novaes AB, et al. Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: Cytokine profile in gingival crevicular fluid, preliminary results. J Periodontol 2009;80:98-105.
32. De Oliveira RR, Novaes AB Jr, Garlet GP, et al. The effect of a single episode of antimicrobial photodynamic therapy in the treatment of experimental periodontitis. Microbiological profile and cytokine pattern in the dog mandible. Lasers Med Sci 2011;26:359-367.
33. Giannopoulou C, Cappuyns I, Cancela J, Cionca N, Mombelli A. Effect of photodynamic therapy, diode laser, and deep scaling on cytokine and acutephase protein levels in gingival crevicular fluid of residual periodontal pockets. J Periodontol 2012;83:1018-1027.
34. King DE, Jiang H, Simkin GO, Obochi MO, Levy JG, Hunt DW. Photodynamic alteration of the surface receptor expression pattern of murine splenic dendritic cells. Scand J Immunol 1999;49:184-192.
35. Hunt DW, Levy JG. Immunomodulatory aspects of photodynamic therapy. Expert Opin Investig Drugs 1998;7:57-64.
36. Séguier S, Souza SL, Sverzut AC, et al. Impact of photodynamic therapy on inflammatory cells during human chronic periodontitis. J Photochem Photobiol B 2010;101:348-354.
37. Braham P, Herron C, Street C, Darveau R. Antimicrobial photodynamic therapy may promote periodontal healing through multiple mechanisms. J Periodontol 2009;80:1790-1798.
38. Carvalho AS, Napimoga MH, Coelho-Campos J, Silva-Filho VJ, Thedei G. Photodynamic therapy reduces bone resorption and decreases inflammatory response in an experimental rat periodontal disease model. Photomed Laser Surg 2011;29:735-740.
39. Andersen R, Loebel N, Hammond D, Wilson M. Treatment of periodontal disease by photodisinfection compared to scaling and root planing. J Clin Dent 2007;18:34-38.
40. Rodrigues IF, Machion L, Casati MZ, et al. Clinical evaluation of the use of locally delivered chlorhexidine in periodontal maintenance therapy. J Periodontol 2007;78:624-628.
41. Slot DE, Kranendonk AA, Paraskevas S, Van Der Weijden F. The effect of a pulsed Nd: YAG laser in non-surgical periodontal therapy. J Periodontol 2009;80:1041-1056.
42. Krohn-Dale I, Bøe OE, Enersen M, Leknes KN. Er: YAG laser in the treatment of periodontal sites with recurring chronic inflammation: A 12-month randomized, controlled clinical trial. J Clin Periodontol 2012;39:745-752.
43. Ratka-Krüger P, Mahl D, Deimling D, et al. Er: YAG laser treatment in supportive periodontal therapy. J Clin Periodontol 2012;39:483-489.
44. Slot DE, Timmerman MF, Versteeg PA, Van Der Velden U, Van Der Weijden FA. Adjunctive clinical effect of a water-cooled Nd: YAG laser in a periodontal maintenance care programme: A randomized controlled trial. J Clin Periodontol 2012;39:1159-1165.
45. Atieh MA. Photodynamic therapy as an adjunctive treatment for chronic periodontitis: A meta-analysis. Lasers Med Sci 2010;25:605-613.
46. Sgolastra F, Petrucci A, Severino M, Graziani F, Gatto R, Monaco A. Adjunctive photodynamic therapy to non-surgical treatment of chronic periodontitis: A systematic review and meta-analysis. J Clin Periodontol 2013;40:514-526.
47. Azarpazhooh A, Shah PS, Tenenbaum HC, Goldberg MB. The effect of photodynamic therapy for periodontitis: A systematic review and meta-analysis. J Periodontol 2010;81:4-14.
48. Braun A, Krause F, Frentzen M, Jepsen S. Removal of root substance with the Vector-system compared with conventional debridement in vitro. J Clin Periodontol 2005;32:153-157.
49. Schmidlin PR, Beuchat M, Busslinger A, Lehmann B, Lutz F. Tooth substance loss resulting from mechanical, sonic and ultrasonic root instrumentation assessed by liquid scintillation. J Clin Periodontol 2001;28:1058-1066.
50. Chung DT, Bogle G, Bernardini M, Stephens D, Riggs ML, Egelberg JH. Pain experienced by patients during periodontal maintenance. J Periodontol 2003;74:1293-1301.