Supraspinal gene transfer by intrathecal adeno-associated virus serotype 5

Frontiers in Neuroanatomy

Volumn 8, Issue AUG, 2014, Pages

  Schuster, Daniel J ^a   Belur, Lalitha R ^a   Riedl, Maureen S ^a   Schnell, Stephen A ^a   Podetz Pedersen, Kelly M ^a   Kitto, Kelley F ^a   McIvor, R Scott ^a   Vulchanova, Lucy ^a   Fairbanks, Carolyn A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

AAV5; Adeno associated; CNS; Intrathecal; Mannitol

Indexed keywords

GREEN FLUORESCENT PROTEIN; NEURON SPECIFIC NUCLEAR PROTEIN;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS 5; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CENTRAL NERVOUS SYSTEM; CEREBRAL PEDUNCLE; CEREBROSPINAL FLUID; CHOROID PLEXUS; CINGULATE GYRUS; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENE TRANSFER; GENICULATE NUCLEUS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MACROGLIA; MALE; MOUSE; NERVE CELL; NONHUMAN; OLFACTORY BULB; PROTEIN EXPRESSION; PURKINJE CELL; SOMATOSENSORY CORTEX; SPINAL GANGLION;

EID: 84905485298     PISSN: None     EISSN: 16625129     Source Type: Journal    
DOI: 10.3389/fnana.2014.00066     Document Type: Article

References (26)

1. Ciesielska, A., Mittermeyer, G., Hadaczek, P., Kells, A. P., Forsayeth, J., and Bankiewicz, K. S. (2011). Anterograde axonal transport of AAV2-GDNF in rat basal ganglia. Mol. Ther. 19, 922-927. doi: 10.1038/mt.2010.248
2. Di Pasquale, G., Davidson, B. L., Stein, C. S., Martins, I., Scudiero, D., Monks, A., et al. (2003). Identification of PDGFR as a receptor for AAV-5 transduction. Nat. Med. 9, 1306-1312. doi: 10.1038/nm929
3. Erlich, S. S., McComb, J. G., Hyman, S., and Weiss, M. H. (1986). Ultrastructural morphology of the olfactory pathway for cerebrospinal fluid drainage in the rabbit. J. Neurosurg. 64, 466-473. doi: 10.3171/jns.1986.64.3.0466
4. Fanselow, M. S., and Dong, H. W. (2010). Are the dorsal and ventral hippocampus functionally distinct structures? Neuron 65, 7-19. doi: 10.1016/j.neuron.2009.11.031
5. Fruttiger, M., Karlsson, L., Hall, A. C., Abramsson, A., Calver, A. R., Bostrom, H., et al. (1999). Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice. Development 126, 457-467.
6. Fu, H., Muenzer, J., Samulski, R. J., Breese, G., Sifford, J., Zeng, X., et al. (2003). Self- complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain. Mol. Ther. 8, 911-917. doi: 10.1016/j.ymthe.2003.08.021
7. Fu, H., Samulski, R. J., McCown, T. J., Picornell, Y. J., Fletcher, D., and Muenzer, J. (2002). Neurological correction of lysosomal storage in a mucopolysaccharidosis IIIB mouse model by adeno-associated virus-mediated gene delivery. Mol. Ther. 5, 42-49. doi: 10.1006/mthe.2001.0514
8. Gray, S. J., Nagabhushan Kalburgi, S., McCown, T. J., and Jude Samulski, R. (2013). Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates. Gene Ther. 20, 450-459. doi: 10.1038/gt.2012.101
9. Hylden, J. L., and Wilcox, G. L. (1980). Intrathecal morphine in mice: a new technique. Eur. J. Pharmacol. 67, 313-316. doi: 10.1016/0014-2999(80) 90515-4
10. Ishii, Y., Oya, T., Zheng, L., Gao, Z., Kawaguchi, M., Sabit, H., et al. (2006). Mouse brains deficient in neuronal PDGF receptor-beta develop normally but are vulnerable to injury. J. Neurochem. 98, 588-600. doi: 10.1111/j.1471-4159.2006.03922.x
11. Iwamoto, N., Watanabe, A., Yamamoto, M., Miyake, N., Kurai, T., Teramoto, A., et al. (2009). Global diffuse distribution in the brain and efficient gene delivery to the dorsal root ganglia by intrathecal injection of adenoassociated viral vector serotype 1. J. Gene Med. 11, 498-505. doi: 10.1002/ jgm.1325
12. Kaemmerer, W. F., Reddy, R. G., Warlick, C. A., Hartung, S. D., McIvor, R. S., and Low, W. C. (2000). In vivo transduction of cerebellar Purkinje cells using adeno-associated virus vectors. Mol. Ther. 2, 446-457. doi: 10.1006/mthe. 2000.0134
13. Kiwic, G., Slusarczyk, K., and Slusarczyk, R. (1998). The central nervous system and the lymphatic system. Lymphatic drainage of the cerebrospinal fluid. Neurol. Neurochir. Pol. 32, 633-641.
14. Mollanji, R., Bozanovic-Sosic, R., Silver, I., Li, B., Kim, C., Midha, R., et al. (2001). Intracranial pressure accommodation is impaired by blocking pathways leading to extracranial lymphatics. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280, R1573-R1581.
15. Morse, D. E., and Low, F. N. (1972). The fine Structure of the pia mater of the rat. Am. J. Anat. 133, 349-367.
16. Paxinos, G., and Franklin, K. B. J. (2001). The Mouse Brain in Stereotaxic Coordinates. San Diego, CA: Academic Press.
17. Reina, M. A., De Leon Casasola Ode, L., Villanueva, M. C., Lopez, A., Maches, F., and De Andres, J. A. (2004). Ultrastructural findings in human spinal pia mater in relation to subarachnoid anesthesia. Anesth. Analg. 98, 1479-1485. doi: 10.1213/01.ANE.0000113240.09354.E9
18. Storek, B., Reinhardt, M., Wang, C., Janssen, W. G., Harder, N. M., Banck, M. S., et al. (2008). Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain. Proc. Natl. Acad. Sci. U.S.A. 105, 1055-1060. doi: 10.1073/pnas.0708003105
19. Towne, C., Pertin, M., Beggah, A. T., Aebischer, P., and Decosterd, I. (2009). Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery. Mol. Pain 5:52. doi: 10.1186/1744-8069-5-52
20. Vulchanova, L., Riedl, M. S., Shuster, S. J., Stone, L. S., Hargreaves, K. M., Buell, G., et al. (1998). P2X3 is expressed by DRG neurons that terminate in inner lamina II. Eur. J. Neurosci. 10, 3470-3478. doi: 10.1046/j.1460-9568.1998. 00355.x
21. Vulchanova, L., Schuster, D. J., Belur, L. R., Riedl, M. S., Podetz-Pedersen, K. M., Kitto, K. F., et al. (2010). Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture. Mol. Pain 6:31. doi: 10.1186/1744-8069-6-31
22. Walters, R. W., Yi, S. M., Keshavjee, S., Brown, K. E., Welsh, M. J., Chiorini, J. A., et al. (2001). Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer. J. Biol. Chem. 276, 20610-20616. doi: 10.1074/jbc.M101559200
23. Watson, G., Bastacky, J., Belichenko, P., Buddhikot, M., Jungles, S., Vellard, M., et al. (2006). Intrathecal administration of AAV vectors for the treatment of lysosomal storage in the brains of MPS I mice. Gene Ther. 13, 917-925.
24. White, E. A., Bienemann, A. S., Sena-Esteves, M., Taylor, H., Bunnun, C., Castrique, E. S., et al. (2011). Evaluation and optimisation of the administration of recombinant adeno-associated viral vectors (Serotypes 2/1, 2/2, 2/rh8, 2/9 and 2/rh10) by convection-enhanced delivery to the striatum. Hum. Gene Ther. 22, 237-251. doi: 10.1089/hum.2010.129
25. Williams, A. E., and Blakemore, W. F. (1990). Pathology of Streptococcal meningitis following intravenous intracisternal and natural routes of infection. Neuropathol. Appl. Neurobiol. 16, 345-356. doi: 10.1111/j.1365-2990.1990.tb01268.x
26. Zolotukhin, S., Potter, M., Zolotukhin, I., Sakai, Y., Loiler, S., Fraites, T. J. Jr., et al. (2002). Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors. Methods 28, 158-167. doi: 10.1016/S1046-2023(02)00220-7