Inhibitory effects of Picrasma quassioides (D.Don) Benn. on airway inflammation in a murine model of allergic asthma

Molecular Medicine Reports

Volumn 10, Issue 3, 2014, Pages 1495-1500

  Shin, Na Rae ^a,b   Shin, In Sik ^a   Jeon, Chan Mi ^a,c   Hong, Ju Mi ^a,d   Oh, Sei Ryang ^a   Hahn, Kyu Woung ^b   Ahn, Kyung Seop ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Hannam University   (South Korea)

^c Chungnam National University   (South Korea)

^d Chungbuk National University   (South Korea)

Author keywords

Airway inflammation; Allergic asthma; Inducible nitric oxide synthase; Picrasma quassioides

Indexed keywords

ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN E; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; LIPOPOLYSACCHARIDE; OVALBUMIN; PICRASMA QUASSIOIDES EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; NITRIC OXIDE; NOS2 PROTEIN, MOUSE; PLANT MEDICINAL PRODUCT;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL COUNT; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; IMMUNOBLOTTING; INFLAMMATION; INFLAMMATORY CELL; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; MUCUS SECRETION; NONHUMAN; PICRASMA; PICRASMA QUASSIOIDES; PROTEIN EXPRESSION; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; ANIMAL; ANTAGONISTS AND INHIBITORS; ASTHMA; BAGG ALBINO MOUSE; BLOOD; CHEMICALLY INDUCED; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHYTOTHERAPY; RESPIRATORY SYSTEM; TUMOR CELL LINE;

ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOGLOBULIN E; INFLAMMATION; INTERLEUKIN-13; INTERLEUKIN-4; INTERLEUKIN-5; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OVALBUMIN; PHYTOTHERAPY; PICRASMA; PLANT PREPARATIONS; RESPIRATORY SYSTEM;

EID: 84905450054     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2322     Document Type: Article

References (16)

1. Prado CM, Martins MA and Tibério IF: Nitric oxide in asthma physiopathology. ISRN Allergy 2011: 832560, 2011.
2. Schuijs MJ, Willart MA, Hammad H and Lambrecht BN: Cytokine targets in airway inflammation. Curr Opin Pharmacol 13: 351-361, 2013.
3. Jiao WH, Gao H, Zhao F, Lin HW, Pan YM, Zhou GX and Yao XS: Anti-inflammatory alkaloids form the stems of Picrasma qussioides BENNET. Chem Pharm Bull (Tokyo) 59: 359-364, 2011.
4. Yin Y, Lee SK and Wang MH: Isolation and biological activities of an alkaloid compound (3-methylcanthin-5,6-dione) from Picrasma quassiodes (D.Don) Benn. Nat Prod Sci 17: 5-9, 2011.
5. Liu JF, Shao M, Zhai DW, Liu K and Wu LJ: Protective effect of 4-methoxy-5-hyfuoxycanthin-6-one, a natural alkaloid, on dextran sulfate sodium-induced rat colitis. Planta Med 75: 142-145, 2009.
6. Fan H, Qi D, Yang M, Fang H, Liu K and Zhao F: In vitro and in vivo anti-inflammatory effects of 4-methoxy-5-hydroxycanthin-6-one, natural alkaloid from Picrasma quassioides. Phytomedicine 20: 319-323, 2013.
7. Ra J, Lee S, Kim HJ, Jang YP, Ahn H and Kim J: Bambusae Caulis in Taeniam extract reduces ovalbumin-induced airway inflammation and T helper 2 responses in mice. J Ethnopharmacol 128: 241-247, 2010.
8. Nader MA, El-Awady MS, Shalaby AA and El-Aqamy DS: Sitagliptin exerts anti-inflammatory and anti-allergic effects in ovalbumin-induced murine model of allergic airway disease. Naunyn Schmidebergs Arch Pharmacol 385: 909-919, 2012.
9. Lee MY, Shin IS, Jeon WY, Lim HS, Kim JH and Ha H: Pinellia ternate Breitenbach attenuates ovalbumin-induced allergic airway inflammation and mucus secretion in a murine model of asthma. Immunopharmacol Immunotoxicol 35: 410-418, 2013.
10. Schmudde I, Laumonnier Y and Köhl J: Anaphylatoxins coordinate innate and adaptive immune responses in allergic asthma. Semin Immunol 25: 2-11, 2013.
11. Shin IS, Lee MY, Lim HS, Ha H, Seo CS, Kim JC and Shin HK: An extract of Crataegus pinnatifida fruit attenuates airway inflammation by modulation of matrix metalloproteinase-9 in ovalbumin induced asthma. PLoS One 7: e45734, 2012.
12. Lee YT, Lee SS, Sun HL, Lu KH, Ku MS, Sheu JN, Ko JL and Lue KH: Effect of the fungal immunomodulatory protein FIP-fve on airway inflammation and cytokine production in mouse asthma model. Cytokine 61: 237-244, 2013.
13. Simoes DC, Xanthou G, Petrochilou K, Panoutsakopoulou V, Roussos C and Gratziou C: Osteopontin deficiency protects against airway remodeling and hyperresponsiveness in chronic asthma. Am J Respir Crit Care Med 179: 894-902, 2009.
14. Shen JJ, Chiang MS, Kuo ML, Leu YL, Hwang TL, Liou CJ and Huang WC: Partially purified extract and viscolin from Viscum coloratum attenuate airway inflammation and eosinophil infiltration in ovalbumin-sensitized mice. J Ethnopharmacol 135: 646-653, 2011.
15. Koarai A, Ichinose M, Sugiura H, Tomaki M, Watanabe M, Yamagata S, Komaki Y, Shirato K and Hattori T: iNOS depletion completely diminishes reactive nitrogen-species formation after an allergic response. Eur Respir J 20: 609-616, 2002.
16. Deshane J, Zmijewski JW, Luther R, Gaggar A, Deshane R, Lai JF, Xu X, Spell M, Estell K, Weaver CT, Abraham E, Schwiebert LM and Chaplin DD: Free radical-producing myeloid-derived regulatory cells: potent activators and suppressors of lung inflammation and airway hyperresponsiveness. Mucosal Immunol 4: 503-518, 2011.