Usnic acid protects LPS-induced acute lung injury in mice through attenuating inflammatory responses and oxidative stress

International Immunopharmacology

Volumn 22, Issue 2, 2014, Pages 371-378

  Su, Zu Qing ^a   Mo, Zhi Zhun ^a   Liao, Jin Bin ^a,b   Feng, Xue Xuan ^a   Liang, Yong Zhuo ^a   Zhang, Xie ^a   Liu, Yu Hong ^a   Chen, Xiao Ying ^a   Chen, Zhi Wei ^a   Su, Zi Ren ^a   Lai, Xiao Ping ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^b GUANGDONG PROVINCIAL HOSPITAL OF CHINESE MEDICINE   (China)

Author keywords

Acute lung injury (ALI); Anti inflammation; Lipopolysaccharide (LPS); Oxidative stress; Usnic acid (UA)

Indexed keywords

ANTIINFLAMMATORY AGENT; GLUTATHIONE; HYDROGEN PEROXIDE; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 2; MALONALDEHYDE; MYELOPEROXIDASE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; USNIC ACID; ANTIOXIDANT; BENZOFURAN DERIVATIVE; CYTOKINE; PEROXIDASE;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL COUNT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME ACTIVITY; INFLAMMATION; INFLAMMATORY CELL; LUNG EDEMA; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; SURVIVAL RATE; ANIMAL; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY;

ACUTE LUNG INJURY; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BENZOFURANS; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; CYTOKINES; GLUTATHIONE; HYDROGEN PEROXIDE; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; OXIDATIVE STRESS; PEROXIDASE; SUPEROXIDE DISMUTASE;

EID: 84905447948     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.06.043     Document Type: Article

References (30)

1. N. Yingkun, W. Zhenyu, L. Jing, L. Xiuyun, and Y. Huimin Stevioside protects LPS-induced acute lung injury in mice Inflammation 36 2013 242 250
2. Y. Liu, H. Wu, Y.C. Nie, J.L. Chen, W.W. Su, and P.B. Li Naringin attenuates acute lung injury in LPS-treated mice by inhibiting NF-kappaB pathway Int Immunopharmacol 11 2011 1606 1612
3. Lorraine B. Ware, and Michael A. Matthay The acute respiratory distress syndrome N Engl J Med 342 2000 1334 1349 (Pubitemid 30408719)
4. L.W. Soromou, N. Chen, L. Jiang, M. Huo, M. Wei, and X. Chu et al. Astragalin attenuates lipopolysaccharide-induced inflammatory responses by down-regulating NF-kappaB signaling pathway Biochem Biophys Res Commun 419 2012 256 261
5. X. Chen, X. Yang, T. Liu, M. Guan, X. Feng, and W. Dong et al. Kaempferol regulates MAPKs and NF-kappaB signaling pathways to attenuate LPS-induced acute lung injury in mice Int Immunopharmacol 14 2012 209 216
6. F.H. Curd, A. Robertson, and R. Stephenson 40. Lichen acids. Part IV. Atranorin J Chem Soc 0 1933 130 133
7. W. Knop Chemisch-physiologische Untersuchung über die Flechten Justus Liebigs Ann Chem 49 2006 103 124
8. C.S. Vijayakumar, S. Viswanathan, M.K. Reddy, S. Parvathavarthini, A.B. Kundu, and E. S. Anti-inflammatory activity of usnic acid Fitoterapia 71 2000 564 566
9. F. Odabasoglu, A. Cakir, H. Suleyman, A. Aslan, Y. Bayir, and M. Halici et al. Gastroprotective and antioxidant effects of usnic acid on indomethacin-induced gastric ulcer in rats J Ethnopharmacol 103 2006 59 65 (Pubitemid 41681142)
10. T. Honda, H. Domon, T. Okui, K. Kajita, R. Amanuma, and K. Yamazaki Balance of inflammatory response in stable gingivitis and progressive periodontitis lesions Clin Exp Immunol 144 2006 35 40
11. P.M. Flood, L. Qian, L.J. Peterson, F. Zhang, J.S. Shi, and H.M. Gao et al. Transcriptional factor NF-kappaB as a target for therapy in Parkinson's disease Park Dis 2011 2011 1 8
12. Z. Huang, G. Zheng, J. Tao, and J. Ruan Anti-inflammatory effects and mechanisms of usnic acid J Wuhan Univ Technol-Mater Sci Ed 26 2011 955 959
13. B. Zhang, Z.-Y. Liu, Y.-Y. Li, Y. Luo, M.-L. Liu, and H.-Y. Dong et al. Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice Eur J Pharm Sci 44 2011 573 579
14. J. Xu, J. Qu, L. Cao, Y. Sai, C. Chen, and L. He et al. Mesenchymal stem cell-based angiopoietin-1 gene therapy for acute lung injury induced by lipopolysaccharide in mice J Pathol 214 2008 472 481 (Pubitemid 351340567)
15. Y. Takao, K. Mikawa, K. Nishina, and H. Obara Attenuation of acute lung injury with propofol in endotoxemia Anesth Analg 100 2005 810 816 (Pubitemid 40300081)
16. P.F.L. Huang, E.A. Oldham, M.J. Keating, and W. Plunkett Superoxide dismutase as a target for the selective killing of cancer cells Nature 407 2000 390 395
17. J. Yang, J.M. Qu, H. Summah, J. Zhang, Y.G. Zhu, and H.N. Jiang Protective effects of imipramine in murine endotoxin-induced acute lung injury Eur J Pharmacol 638 2010 128 133
18. X. Zhang, H. Huang, T. Yang, Y. Ye, J. Shan, and Z. Yin et al. Chlorogenic acid protects mice against lipopolysaccharide-induced acute lung injury Injury 41 2010 746 752
19. Yun Feng Ni, Tao Jiang, Qing Shu Cheng, Zhong Ping Gu, Yi Fang Zhu, and Zhi Pei Zhang et al. Protective effect of magnolol on lipopolysaccharide-induced acute lung injury in mice Inflammation 35 2012 1861 1866
20. X.J. Chen, B. Zhang, S.J. Hou, Y. Shi, D.Q. Xu, and Y.X. Wang et al. Osthole improves acute lung injury in mice by up-regulating Nrf-2/thioredoxin 1 Respir Physiol Neurobiol 188 2013 214 222
21. M. Moradi, M. Mojtahedzadeh, A. Mandegari, M.S. Soltan-Sharifi, A. Najafi, and M.R. Khajavi et al. The role of glutathione-S-transferase polymorphisms on clinical outcome of ALI/ARDS patient treated with N-acetylcysteine Respir Med 103 2009 434 441
22. C.W. Chow, M.T. Herrera Abreu, T. Suzuki, and G.P. Downey Oxidative stress and acute lung injury Am J Respir Cell Mol Biol 29 2003 427 431 (Pubitemid 37222680)
23. P.K. Fu, C.Y. Yang, T.H. Tsai, and C.L. Hsieh Moutan cortex radicis improves lipopolysaccharide-induced acute lung injury in rats through anti-inflammation Phytomedicine 19 2012 1206 1215
24. P. Wang, X.L. Ye, R. Liu, H.L. Chen, X. Liang, and W.L. Li et al. Mechanism of acute lung injury due to phosgene exposition and its protection by cafeic acid phenethyl ester in the rat Exp Toxicol Pathol 65 2011 311 318
25. K. Raghavendran, G.S. Pryhuber, P.R. Chess, B.A. Davidson, P.R. Knight, and R.H. Notter Pharmacotherapy of acute lung injury and acute respiratory distress syndrome Curr Med Chem 15 2008 1911 1924
26. J. Reutershan, M.A. Morris, T.L. Burcin, D.F. Smith, D. Chang, and M.S. Saprito et al. Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung J Clin Invest 116 2006 695 702 (Pubitemid 43326878)
27. L.W. Soromou, X. Chu, L. Jiang, M. Wei, M. Huo, and N. Chen et al. In vitro and in vivo protection provided by pinocembrin against lipopolysaccharide-induced inflammatory responses Int Immunopharmacol 14 2012 66 74
28. J. Reutershan, A. Basit, E.V. Galkina, and K. Ley Sequential recruitment of neutrophils into lung and bronchoalveolar lavage fluid in LPS-induced acute lung injury Am J Physiol Lung Cell Mol Physiol 289 2005 L807 L815
29. X. Chu, K. Song, K. Xu, X. Zhang, X. Zhang, and Y. Song et al. Ceftiofur attenuates lipopolysaccharide-induced acute lung injury Int Immunopharmacol 10 2010 600 604
30. J. Grommes, and O. Soehnlein Contribution of neutrophils to acute lung injury Mol Med 17 2011 293 307