Platelet-rich plasma affects bacterial growth in vitro

Cytotherapy

Volumn 16, Issue 9, 2014, Pages 1294-1304

  Mariani, Erminia ^a,b   Filardo, Giuseppe ^a   Canella, Valentina ^a   Berlingeri, Andrea ^c   Bielli, Alessandra ^c   Cattini, Luca ^a   Landini, Maria Paola ^c   Kon, Elizaveta ^a   Marcacci, Maurilio ^a   Facchini, Andrea ^a,b  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Bacterial growth; Kinocidins; Microbicidal activity; Microbicidal proteins; Nosocomial infections; Platelet rich plasma

Indexed keywords

AGAR; CHEMOKINE; CHEMOKINE LIGAND 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MICROBICIDAL PROTEIN; PROTEIN; RANTES; UNCLASSIFIED DRUG; TOPICAL ANTIINFECTIVE AGENT;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM CONTAMINATION; CONTROLLED STUDY; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; GROWTH INHIBITION; HEALING; HOSPITAL INFECTION; HUMAN; HUMAN TISSUE; IMMUNOASSAY; IN VITRO STUDY; INCUBATION TIME; INNATE IMMUNITY; KLEBSIELLA PNEUMONIAE; MALE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; SURGICAL INFECTION; THROMBOCYTE; THROMBOCYTE POOR PLASMA; THROMBOCYTE RICH PLASMA; TISSUE ENGINEERING; TISSUE REGENERATION; ADULT; BACTERIA; BACTERIAL INFECTIONS; CELL CULTURE; CELL GROWTH; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY; SURGERY; SURGICAL WOUND INFECTION;

ADULT; ANTI-INFECTIVE AGENTS, LOCAL; BACTERIA; BACTERIAL INFECTIONS; CELL GROWTH PROCESSES; CELLS, CULTURED; CHEMOKINES; GUIDED TISSUE REGENERATION; HUMANS; MALE; PLATELET-RICH PLASMA; SURGICAL PROCEDURES, OPERATIVE; SURGICAL WOUND INFECTION; TISSUE ENGINEERING;

EID: 84905441854     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2014.06.003     Document Type: Article

References (32)

1. Anitua E., Sanchez M., Orive G. Potential of endogenous regenerative technology for in situ regenerative medicine. Adv Drug Deliv Rev 2010, 62:741-752.
2. Cole B.J., Seroyer S.T., Filardo G., Bajaj S., Fortier L.A. Platelet-rich plasma: where are we now and where are we going?. Sports Health 2010, 2:203-210.
3. Filardo G., Presti M.L., Kon E., Marcacci M. Nonoperative biological treatment approach for partial Achilles tendon lesion. Orthopedics 2010, 33:120-123.
4. Torricelli P., Fini M., Filardo G., Tschon M., Pischedda M., Pacorini A., et al. Regenerative medicine for the treatment of musculoskeletal overuse injuries in competition horses. Int Orthop 2011, 35:1569-1576.
5. Tschon M., Fini M., Giardino R., Filardo G., Dallari D., Torricelli P., et al. Lights and shadows concerning platelet products for musculoskeletal regeneration. Front Biosci 2011, 3:96-107.
6. Sanchez-Ilarduya M.B., Trouche E., Tejero R., Orive G., Reviakine I., Anitua E. Time-dependent release of growth factors from implant surfaces treated with plasma rich in growth factors. J Biomed Mater Res A 2013, 101:1478-1488.
7. Yeaman M.R. Platelets in defense against bacterial pathogens. Cell Mol Life Sci 2010, 67:525-544.
8. Dohan Ehrenfest D.M., Sammartino G., Shibli J.A., Wang H.L., Zou D.R., Bernard J.P. Guidelines for the publication of articles related to platelet concentrates (platelet-rich plasma-PRP, or platelet-rich fibrin-PRF): the international classification of the POSEIDO. POSEIDO J 2013, 1:17-27.
9. Wiesner J., Vilcinskas A. The ancient arm of the human immune system. Virulence 2010, 1(5):440-464.
10. Zalavras C.G., Patzakis M.J., Holtom P. Local antibiotic therapy in the treatment of open fractures and osteomyelitis. Clin Orthop Relat Res 2004, 427:86-93.
11. Thanni L.O., Osinupebi O.A., ji-Agboola M. Prevalence of bacterial pathogens in infected wounds in a tertiary hospital, 1995-2001: any change in trend?. J Natl Med Assoc 2003, 95:1189-1195.
12. Lautenbach D., Patel J.B., Bilker W.B., Edelstein P.H., Fishman N.O. Extended-spectrum B-lactamase-producing Escherichia coli and Klebsiella pneumoniae risk factors for infection and impact of resistance on outcomes. J Assoc Physicians India 2013, 12(58):1162-1171.
13. Anitua E., Orive G., Aguirre J.J., Andia I. Five-year clinical evaluation of short dental implants placed in posterior areas: a retrospective study. J Periodontol 2008, 79:42-48.
14. Perut F., Filardo G., Mariani E., Cenacchi A., Pratelli L., Devescovi V., et al. Preparation method and growth factor content of platelet concentrate influence the osteogenic differentiation of bone marrow stromal cells. Cytotherapy 2013, 15:830-839.
15. Zuluaga A.F., Galvis W., Jaimes F., Vesga O. Lack of microbiological concordance between bone and non-bone specimens in chronic osteomyelitis: an observational study. BMC Infect Dis 2002, 2:8.
16. Mader J.T., Calhoum J. Osteomyelitis. Principles and Practice of Infectious Diseases 2000, 1182-1196. Churchill Livingston, Philadelphia. G.L. Mandell, J.E. Bennet, R. Dolin (Eds.).
17. Moojen D.J., Everts P.A., Schure R.M., Overdevest E.P., van Z.A., Knape J.T., et al. Antimicrobial activity of platelet-leukocyte gel against Staphylococcus aureus. J Orthop Res 2008, 26:404-410.
18. Prabhakara R., Harro J.M., Leid J.G., Harris M., Shirtliff M.E. Murine immune response to a chronic Staphylococcus aureus biofilm infection. Infect Immun 2011, 79:1789-1796.
19. Mariani E., Cattini L., Neri S., Malavolta M., Mocchegiani E., Ravaglia G., et al. Simultaneous evaluation of circulating chemokine and cytokine profiles in elderly subjects by multiplex technology: relationship with zinc status. Biogerontology 2006, 7:449-459.
20. Anitua E., Andia I., Ardanza B., Nurden P., Nurden A.T. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004, 91:4-15.
21. Anitua E., Alonso R., Girbau C., Aguirre J.J., Muruzabal F., Orive G. Antibacterial effect of plasma rich in growth factors [PRGF(R)-Endoret(R)] against Staphylococcus aureus and Staphylococcus epidermidis strains. Clin Exp Dermatol 2012, 37:652-657.
22. Bielecki T.M., Gazdzik T.S., Arendt J., Szczepanski T., Krol W., Wielkoszynski T. Antibacterial effect of autologous platelet gel enriched with growth factors and other active substances: an in vitro study. J Bone Joint Surg Br 2007, 89:417-420.
23. Chen L., Wang C., Liu H., Liu G., Ran X. Antibacterial effect of autologous platelet-rich gel derived from subjects with diabetic dermal ulcers in vitro. J Diabetes Res 2013, 269527.
24. Burnouf T., Chou M.L., Wu Y.W., Su C.Y., Lee L.W. Antimicrobial activity of platelet (PLT)-poor plasma, PLT-rich plasma, PLT gel, and solvent/detergent-treated PLT lysate biomaterials against wound bacteria. Transfusion 2013, 53:138-146.
25. Drago L., Bortolin M., Vassena C., Taschieri S., Del F.M. Antimicrobial activity of pure platelet-rich plasma against microorganisms isolated from oral cavity. BMC Microbiol 2013, 13:47.
26. Stuart C.H., Schwartz S.A., Beeson T.J., Owatz C.B. Enterococcus faecalis: its role in root canal treatment failure and current concepts in retreatment. J Endod 2006, 32:93-98.
27. Tang Y.Q., Yeaman M.R., Selsted M.E. Antimicrobial peptides from human platelets. Infect Immun 2002, 70:6524-6533.
28. Yount N.Y., Yeaman M.R. Multidimensional signatures in antimicrobial peptides. Proc Natl Acad Sci U S A 2004, 101:7363-7368.
29. Yount N.Y., Waring A.J., Gank K.D., Welch W.H., Kupferwasser D., Yeaman M.R. Structural correlates of antimicrobial efficacy in IL-8 and related human kinocidins. Biochim Biophys Acta 2007, 1768:598-608.
30. Yang D., Chen Q., Hoover D.M., Staley P., Tucker K.D., Lubkowski J., et al. Many chemokines including CCL20/MIP-3alpha display antimicrobial activity. J Leukoc Biol 2003, 74:448-455.
31. Ohta K., Nishi H., Fukui A., Shigeishi H., Takechi M., Kamata N. CX3CL1 expression induced by Candida albicans in oral fibroblasts. FEMS Immunol Med Microbiol 2010, 60:179-185.
32. Cole A.M., Ganz T., Liese A.M., Burdick M.D., Liu L., Strieter R.M. Cutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity. J Immunol 2001, 167:623-627.