T cells increase before zoster and pd-1 expression increases at the time of zoster in immunosuppressed nonhuman primates latently infected with simian varicella virus

Journal of NeuroVirology

Volumn 20, Issue 3, 2014, Pages 309-313

  James, Stephanie F ^a   Traina Dorge, Vicki ^a   Deharo, Eileen ^a   Wellish, Mary ^a   Palmer, Brent E ^a   Gilden, Don ^a,b   Mahalingam, Ravi ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

Author keywords

PD 1; Simian varicella virus; T cells; Varicella zoster virus

Indexed keywords

PROGRAMMED DEATH 1 RECEPTOR; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; PREDNISONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CHICKENPOX; CONTROLLED STUDY; EFFECTOR CELL; IMMUNE DEFICIENCY; IMMUNOPATHOGENESIS; IMMUNOPHENOTYPING; LATENT VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHESUS MONKEY; SIMIAN VARICELLA VIRUS; SPATIAL MEMORY TEST; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; VARICELLA ZOSTER VIRUS; VIRUS EXPRESSION; VIRUS PATHOGENESIS; VIRUS REACTIVATION; AGING; ANIMAL; CD4+ T LYMPHOCYTE; HERPES ZOSTER; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; PATHOLOGY; VIROLOGY; VIRUS ACTIVATION;

CERCOPITHECINE HERPESVIRUS 9; HUMAN HERPESVIRUS 3; MACACA MULATTA; PRIMATES; SAL VIEJA VIRUS;

AGING; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; GLUCOCORTICOIDS; HERPES ZOSTER; HERPESVIRUS 3, HUMAN; IMMUNOLOGIC MEMORY; IMMUNOSUPPRESSIVE AGENTS; MACACA MULATTA; PREDNISONE; PROGRAMMED CELL DEATH 1 RECEPTOR; VIRUS ACTIVATION;

EID: 84905396994     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-014-0237-7     Document Type: Article

References (15)

1. Asano Y, Suga S, Yoshikawa T, Kobayashi I, Yazaki T, Shibata M, Tsuzuki K, Ito S (1994) Experience and reason: twenty-year follow-up of protective immunity of the Oka strain live varicella vaccine. Pediatrics 94:524-526 (Pubitemid 24295036)
2. Bilgrami S, Chakraborty NG, Rodriguez-Pinero F, Khan AM, Feingold JM, Bona RD, Edwards RL, Dorsky D, Clive J, Mukherji B, Tutschka PJ (1999) Varicella zoster virus infection associated with high-dose chemotherapy and autologous stem-cell rescue. Bone Marrow Transplant 23:469-474 (Pubitemid 29117038)
3. D'Souza M, Fontenot AP, Mack DG, Lozupone C, Dillon S, Meditz A, Wilson CC, Connick E, Palmer BE (2007) Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction. J Immunol 179:1979-1987
4. Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker B (2006) PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443:350-354 (Pubitemid 44435155)
5. Finnefrock AC, Tang A, Li F, Freed DC, Feng M, Cox KS, Sykes KJ, Guare JP, Miller MD, Olsen DB, Hazuda DJ, Shiver JW, Casimiro DR, Fu TM (2009) PD-1 blockade in rhesus macaques: impact on chronic infection and prophylactic vaccination. J Immunol 182:980-998
6. Gilden DH, Dueland AN, Cohrs R, Martin JR, Kleinschmidt-DeMasters BK, Mahalingam R (1991) Preherpetic neuralgia. Neurology 41:1215-1218
7. Hayward A, Levin M, Wolf W, Angelova G, Gilden D (1991) Varicella-zoster virus-specific immunity after herpes zoster. J Infect Dis 163:873-875
8. Larrubia JR, Benito-Martínez S, Miquel J, Calvino M, Sanz-de-Villalobos E, Parra-Cid T (2009) Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C. World J Gastroenterol 15:5129-5140
9. Locksley RM, Flournoy N, Sullivan KM, Meyers JD (1985) Infection with varicella-zoster virus after marrow transplantation. J Infect Dis 152:1172-1181 (Pubitemid 16215593)
10. Mahalingam R, Wellish M, Cohrs R, Debrus S, Piette J, Rentier B, Gilden D (1996) Expression of protein encoded by varicella zoster virus open reading frame 63 in latently infected human ganglionic neurons. Proc Natl Acad Sci 93:2122-2124 (Pubitemid 26079891)
11. Mahalingam R, Traina-Dorge V, Wellish M, Deharo E, Singletary ML, Ribka EP, Sanford R, Gilden D (2010) Latent simian varicella virus reactivates in monkeys treated with tacrolimus with or without exposure to irradiation. J Neurovirol 16:342-354
12. Messaoudi I, Barron A, Wellish M, Engelmann F, Legasse A, Planer S, Gilden D, Nikolich-Zugich J, Mahalingam R (2009) Simian varicella virus infection of rhesus macaques recapitulates essential features of varicella zoster virus infection in humans. PLoS Pathog 5(11):e1000657
13. Ouwendijk WJ, Mahalingam R, de Swart RL, Haagmans BL, van Amerongen G, Getu S, Gilden D, Osterhaus AD, Verjans GM (2013) T-cell tropism of simian varicella virus during primary infection. PLoS Pathog 9(5):e1003368
14. Urbani S, Amadei B, Tola D, Massari M, Schivazappa S, Missale G, Ferrari C (2006) PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion. J Virol 80:11398-11403 (Pubitemid 44706581)
15. Weinberg A, Zhang JH, Oxman MN, Johnson GR, Hayward AR, Caulfield MJ, Irwin MR, Clair J, Smith JG, Stanley H, Marchese RD, Harbecke R, Williams HM, Chan IS, Arbeit RD, Gershon AA, Schödel F, Morrison VA, Kauffman CA, Straus SE, Schmader KE, Davis LE, Levin MJ, US Department of Veterans Affairs (VA) Cooperative Studies Program Shingles Prevention Study Investigators (2009) Varicella-zoster virus-specific immune responses to herpes zoster in elderly participants in a trial of a clinically effective zoster vaccine. J Infect Dis 200:1068-1077