Molybdopterin biosynthesis: Trapping of intermediates for the MoaA-catalyzed reaction using 2′-deoxyGTP and 2′-chloroGTP as substrate analogues.

Journal of the American Chemical Society

Volumn 136, Issue 30, 2014, Pages 10609-10614

  Mehta, Angad P ^a   Abdelwahed, Sameh H ^a   Xu, Hui ^a   Begley, Tadhg P ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMS; BIOCHEMISTRY; BIOSYNTHESIS; CATALYSIS; FREE RADICAL REACTIONS;

HYDROGEN-ATOM TRANSFER; MOLYBDOPTERIN; PLAUSIBLE MECHANISMS; REACTION SEQUENCES; S-ADENOSYLMETHIONINE; TRIPHOSPHATE;

REACTION INTERMEDIATES;

2' CHLOROGUANOSINE TRIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE DERIVATIVE; MOAA ENZYME; MOLYBDOPTERIN; PURINE; RIBOSE; S ADENOSYLMETHIONINE; S ADENOSYLMETHIONINE ENZYME; UNCLASSIFIED DRUG; COENZYME; ESCHERICHIA COLI PROTEIN; GUANOSINE TRIPHOSPHATE; ISOMERASE; METALLOPROTEIN; MOAA PROTEIN, E COLI; MOLYBDENUM COFACTOR; PTERIDINE DERIVATIVE;

ARTICLE; BIOSYNTHESIS; CATALYST; CHEMICAL MODIFICATION; DERIVATIZATION; ENZYME ASSAY; ENZYME MECHANISM; ENZYME SUBSTRATE; NONHUMAN; PROTON TRANSPORT; REACTION ANALYSIS; ANALOGS AND DERIVATIVES; COENZYME; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; HALOGENATION; METABOLISM;

COENZYMES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GUANOSINE TRIPHOSPHATE; HALOGENATION; ISOMERASES; METALLOPROTEINS; PTERIDINES; SUBSTRATE SPECIFICITY;

EID: 84905269965     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja502663k     Document Type: Article

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