Chloride channel blockade relaxes airway smooth muscle and potentiates relaxation by β-agonists

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 307, Issue 3, 2014, Pages

  Danielsson, Jennifer ^a   Yim, Peter ^a   Rinderspacher, Alison ^a   Fu, Xiao Wen ^a   Zhang, Yi ^a   Landry, Donald W ^a   Emala, Charles W ^a  

^a Department of Anesthesiology Columbia University ^*  (United States)

Author keywords

Bumetanide; Electrophysiology; Niflumic acid; NKCC; Organ bath

Indexed keywords

5 CHLORO 2 (1 NAPHTHYL METHYLAMINO)]BENZOIC ACID; 5 CHLORO 2 [(4 CHLOROBENZYL)]BENZOIC ACID; ACETYLCHOLINE; ANTHRANILIC ACID DERIVATIVE; BRONCHODILATING AGENT; BUMETANIDE; CHLORIDE CHANNEL BLOCKING AGENT; ISOPRENALINE; TETRYLAMMONIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BREATHING MUSCLE; CELL MEMBRANE; CHLORIDE TRANSPORT; DOSE RESPONSE; DRUG POTENTIATION; EX VIVO STUDY; HUMAN; HUMAN TISSUE; HYPERPOLARIZATION; KIDNEY; MEMBRANE DEPOLARIZATION; NONHUMAN; PLASMA CELL; POTASSIUM TRANSPORT; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; TRACHEA;

BUMETANIDE; ELECTROPHYSIOLOGY; NIFLUMIC ACID; NKCC; ORGAN BATH;

ACETYLCHOLINE; ADRENERGIC BETA-AGONISTS; ANIMALS; ASTHMA; CELL MEMBRANE; CHLORIDE CHANNELS; CHLORIDES; GUINEA PIGS; HUMANS; ISOPROTERENOL; MALE; MEMBRANE POTENTIALS; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; TETRAETHYLAMMONIUM; TRACHEA;

EID: 84905243186     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00351.2013     Document Type: Article

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