Expression of complement messenger RNAs by human endothelial cells

Brain Research

Volumn 871, Issue 1, 2000, Pages 1-6

  Klegeris, Andis ^a   Bissonnette, Christopher J ^a   Dorovini Zis, Katerina ^b   McGeer, Patrick L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VANCOUVER GENERAL HOSPITAL   (Canada)

Author keywords

Complement classical pathway; Human brain; Inflammation; Polymerase chain reaction; Vascular endothelium

Indexed keywords

COMPLEMENT; COMPLEMENTARY DNA; MESSENGER RNA;

ARTICLE; COMPLEMENT SYSTEM; CONTROLLED STUDY; ENCEPHALITIS; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PATHOGENICITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

CELL LINE; CELLS, CULTURED; CEREBROVASCULAR CIRCULATION; COMPLEMENT SYSTEM PROTEINS; ENDOTHELIUM, VASCULAR; HUMANS; MICROCIRCULATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC; UMBILICAL VEINS;

EID: 0034648102     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02253-8     Document Type: Article

References (36)

1. S.R. Barnum, Complement biosynthesis in the central nervous system, Crit. Rev. Oral Biol. Med. 6 (1995) 132-146.
2. E. Bassenge, Endothelial function in different organs, Progress Cardiovasc. Dis. 39 (1996) 209-228.
3. R.A. Brooimans, A.A. Van der Ark, M. Tomita, L.A. Van Es, M.R. Daha, CD59 expressed by human endothelial cells functions as a protective molecule against complement-mediated lysis, Eur. J. Immunol. 22 (1992) 791-797.
4. F. Coria, I. Rubio, Cerebral amyloid angiopathies, Neuropathol. Appl. Neurobiol. 22 (1996) 216-227.
5. K. Dorovini-Zis, R. Prameya, P.D. Bowman, Culture and characterization of microvascular endothelial cells derived from human brain, Lab. Invest. 64 (1991) 425-436.
6. P. Eikelenboom, C.E. Hack, J.M. Rozemuller, F.C. Stam, Complement activation in amyloid plaques in Alzheimer's dementia, Virchows Arch. B Cell Pathol. 56 (1989) 259-262.
7. D. Guc, P. Gulati, C. Lemercier, D. Lappin, G.D. Birnie, K. Whaley, Expression of the components and regulatory proteins of the alternative complement pathway and the membrane attack complex in normal and diseased synovium, Rheumatol. Int. 13 (1993) 139-146.
8. P. Gulati, D. Guc, C. Lemercier, D. Lappin, K. Whaley, Expression of the components and regulatory proteins of the classical pathway of complement in normal and diseased synovium, Rheumatol. Int. 14 (1994) 13-19.
9. V. Hachinski, D.G. Munoz, Cerebrovascular pathology in Alzheimer's disease: cause, effect or epiphenomenon?, Ann. New York Acad. Sci. 826 (1997) 1-6.
10. S.E. Hughes, Functional characterization of the spontaneously transformed human umbilical vein endothelial cell line ECV304: use in an in vitro model of angiogenesis, Exp. Cell Res. 225 (1996) 171-185.
11. E.A. Jaffe, R.L. Nachman, C.G. Becker, C.R. Minick, Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria, J. Clin. Invest. 52 (1973) 2745-2756.
12. E. Johnson, G. Hetland, Human umbilical vein endothelial cells synthesize functional C3, C5, C6, C8 and C9 in vitro, Scand. J. Immunol. 33 (1991) 667-671.
13. N. Julen, H. Dauchel, C. Lemercier, R.B. Sim, M. Fontaine, J. Ripoche, In vitro biosynthesis of complement factor I by human endothelial cells, Eur. J. Immunol. 22 (1992) 213-217.
14. R.N. Kalaria, Cerebral vessels in ageing and Alzheimer's disease, Pharmacol. Ther. 72 (1996) 193-214.
15. D.F. Lappin, D. Guc, A. Hill, T. McShane, K. Whaley, Effect of interferon-gamma on complement gene expression in different cell types, Biochem. J. 281 (1992) 437-442.
16. J.A. Martiney, C. Cuff, M. Litwak, J. Berman, C.F. Brosnan, Cytokine-induced inflammation in the central nervous system revisited, Neurochem. Res. 23 (1998) 349-359.
17. P.L. McGeer, H. Akiyama, S. Itagaki, E.G. McGeer, Immune system response in Alzheimer's disease, Can. J. Neurol. Sci. 16 (1989) 516-527.
18. P.L. McGeer, E.G. McGeer, The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases, Brain Res. Rev. 21 (1995) 195-218.
19. B.P. Morgan, Physiology and pathophysiology of complement: progress and trends, Crit. Rev. Clin. Lab. Sci. 32 (1995) 265-298.
20. B.P. Morgan, P. Gasque, Expression of complement in the brain: role in health and disease, Immunol. Today 17 (1996) 461-466.
21. Z. Nagy, M. Vastag, J. Skopal, K. Kolev, R. Machovich, J. Kramer, I. Karadi, M. Toth, Human brain microvessel endothelial cell culture as a model system to study vascular factors of ischemic brain, Keio J. Med. 45 (1996) 200-206.
22. R. Natte, H.V. Vinters, M.L. Maat-Schieman, M. Bornebroek, J. Haan, R.A. Roos, S.G. Van Duinen, Microvasculopathy is associated with the number of cerebrovascular lesions in hereditary cerebral hemorrhage with amyloidosis, Dutch type, Stroke 29 (1998) 1588-1594.
23. R.R. Nepomuceno, A.J. Tenner, C1qRP, the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets, J. Immunol. 160 (1998) 1929-1935.
24. V.H. Perry, D.C. Anthony, S.J. Bolton, H.C. Brown, The blood-brain barrier and the inflammatory response, Mol. Med. Today 3 (1997) 335-341.
25. M.M. Ruchoux, C.A. Maurage, CADASIL: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, J. Neuropathol. Exp. Neurol. 56 (1997) 947-964.
26. H.L. Schieferdecker, E. Rothermel, A. Timmermann, O. Gotze, K. Jungermann, Anaphylatoxin C5a receptor mRNA is strongly expressed in Kupffer and stellate cells and weakly in sinusoidal endothelial cells but not in hepatocytes of normal rat liver, FEBS Lett. 406 (1997) 305-309.
27. N.S. Sheerin, W. Zhou, S. Adler, S.H. Sacks, TNF-alpha regulation of C3 gene expression and protein biosynthesis in rat glomerular endothelial cells, Kidney Int. 51 (1997) 703-710.
28. Y. Shen, R. Li, E.G. McGeer, P.L. McGeer, Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain, Brain Res. 769 (1997) 391-395.
29. C.D. Stehouwer, J. Lambert, A.J. Donker, V.W. Van Hinsbergh, Endothelial dysfunction and pathogenesis of diabetic angiopathy, Cardiovasc. Res. 34 (1997) 55-68.
30. K. Takahashi, Y. Sawasaki, J. Hata, K. Mukai, T. Goto, Spontaneous transformation and immortalization of human endothelial cells, In Vitro Cell. Dev. Biol. 26 (1990) 265-274.
31. K. Terai, D.G. Walker, E.G. McGeer, P.L. McGeer, Neurons express proteins of the classical complement pathway in Alzheimer disease, Brain Res. 769 (1997) 385-390.
32. S. Tomlinson, Complement defense mechanisms, Curr. Opin. Immunol. 5 (1993) 83-89.
33. M. Vastag, J. Skopal, J. Kramer, K. Kolev, Z. Voko, E. Csonka, R. Machovich, Z. Nagy, Endothelial cells cultured from human brain microvessels produce complement proteins factor H, factor B, Cl Inhibitor, and C4, Immunobiol. 199 (1998) 5-13.
34. L. Verga, B. Frangione, F. Tagliavini, G. Giaccone, A. Migheli, O. Bugiani, Alzheimer patients and Down patients: cerebral preamyloid deposits differ ultrastructurally and histochemically from the amyloid of senile plaques, Neurosci. Lett. 105 (1989) 294-299.
35. S. Webster, L.F. Lue, L. Brachova, A.J. Tenner, P.L. McGeer, K. Terai, D.G. Walker, B. Bradt, N.R. Cooper, J. Rogers, Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease, Neurobiol. Aging 18 (1997) 415-421.
36. K. Yasojima, C. Schwab, E.G. McGeer, P.L. McGeer, Human heart generates complement proteins that are upregulated and activated after myocardial infarction, Circ. Res. 83 (1998) 860-869.