Characterization of KPC-2-Producing Escherichia coli, Citrobacter freundii, Enterobacter cloacae, Enterobacter aerogenes, and Klebsiella oxytoca Isolates from a Chinese hospital

Microbial Drug Resistance

Volumn 20, Issue 4, 2014, Pages 264-269

  Luo, Yanping ^a   Yang, Jiyong ^a   Ye, Liyan ^a   Guo, Lin ^a   Zhao, Qiang ^a   Chen, Rong ^a   Chen, Yong ^b   Han, Xuelin ^b   Zhao, Jingya ^b   Tian, Shuguang ^b   Han, Li ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ 3; CARBAPENEM; CEPHALOSPORIN; QUINOLONE; RNA 16S; ANTIINFECTIVE AGENT; BETA LACTAMASE; BETA-LACTAMASE KPC-2; CARBAPENEM DERIVATIVE; CEPHALOSPORIN DERIVATIVE; KSGA METHYLTRANSFERASE; METHYLTRANSFERASE; TRANSPOSON;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; CARBAPENEMASE PRODUCING ENTEROBACTERIACEAE; CHINA; CITROBACTER FREUNDII; CLINICAL ARTICLE; CONTROLLED STUDY; ENTEROBACTER AEROGENES; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; GENE INSERTION; GENE STRUCTURE; GENETIC RESISTANCE; GENETIC VARIABILITY; GENOTYPE; HUMAN; KLEBSIELLA OXYTOCA; NONHUMAN; OUTCOME ASSESSMENT; PLASMID; PRIORITY JOURNAL; TRANSPOSON; CROSS INFECTION; DRUG EFFECTS; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; ENZYMOLOGY; GENE EXPRESSION; GENETICS; HOSPITAL; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MORTALITY; MULTIDRUG RESISTANCE; PATHOGENICITY; SURVIVAL; TRANSMISSION;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; CARBAPENEMS; CEPHALOSPORINS; CHINA; CROSS INFECTION; DNA TRANSPOSABLE ELEMENTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; GENE EXPRESSION; HOSPITALS; HUMANS; METHYLTRANSFERASES; MICROBIAL SENSITIVITY TESTS; PLASMIDS; SURVIVAL ANALYSIS;

EID: 84905190450     PISSN: 10766294     EISSN: 19318448     Source Type: Journal    
DOI: 10.1089/mdr.2013.0150     Document Type: Article

References (15)

1. [CLSI] Clinical and Laboratory Standards Institute. 2012. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement (M100-S22). Clinical and Laboratory Standards Institute, Wayne, Pennsylvania.
2. Cuzon, G., T. Naas, and P. Nordmann. 2011. Functional characterization of Tn4401, a Tn3-based transposon involved in blaKPC gene mobilization. Antimicrob. Agents Chemother. 55:5370-5373.
3. Hu, Y.Y., J.C. Cai, R. Zhang, H.W. Zhou, Q. Sun, and G.X. Chen. 2012. Emergence of Proteus mirabilis harboring blaKPC-2 and qnrD in a Chinese Hospital. Antimicrob. Agents Chemother. 56:2278-2282.
4. Li, G., Q. Wei, Y. Wang, X. Du, Y. Zhao, and X. Jiang. 2011. Novel genetic environment of the plasmid-mediated KPC-3 gene detected in Escherichia coli and Citrobacter freundii isolates from China. Eur. J. Clin. Microbiol. Infect. Dis. 30:575-580.
5. Naas, T., G. Cuzon, M.V. Villegas, M.F. Lartigue, J.P. Quinn, and P. Nordmann. 2008. Genetic structures at the origin of acquisition of the beta-lactamase bla KPC gene. Antimicrob. Agents Chemother. 52:1257-1263.
6. Nordmann, P., G. Cuzon, and T. Naas. 2009. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect. Dis. 9:228-236.
7. Pfeifer, Y., A. Cullik, and W. Witte. 2010. Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens. Int. J. Med. Microbiol. 300:371-379.
8. Ribot, E.M., M.A. Fair, R. Gautom, D.N. Cameron, S.B. Hunter, B. Swaminathan, and T.J. Barrett. 2006. Standardization of pulsed-field gel electrophoresis protocols for the subtyping of Escherichia coli O157:H7, Salmonella, and Shigella for PulseNet. Foodborne Pathog. Dis. 3:59-67.
9. Shen, P., Z. Wei, Y. Jiang, X. Du, S. Ji, Y. Yu, and L. Li. 2009. Novel genetic environment of the carbapenemhydrolyzing beta-lactamase KPC-2 among Enterobacteriaceae in China. Antimicrob. Agents Chemother. 53:4333-4338.
10. Sheng, J.F., J.J. Li, S. Tu, Z.K. Sheng, S. Bi, M.H. Zhu, X.M. Shen, and L.J. Li. 2012. blaKPC and rmtB on a single plasmid in Enterobacter amnigenus and Klebsiella pneumoniae isolates from the same patient. Eur. J. Clin. Microbiol. Infect. Dis. 31:1585-1591.
11. Tzouvelekis, L.S., A. Markogiannakis, M. Psichogiou, P.T. Tassios, and G.L. Daikos. 2012. Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions. Clin. Microbiol. Rev. 25:682-707.
12. Yang, J., Y. Chen, X. Jia, Y. Luo, Q. Song, W. Zhao, Y. Wang, H. Liu, D. Zheng, Y. Xia, et al. 2012. Dissemination and characterization of NDM-1-producing Acinetobacter pittii in an intensive care unit in China. Clin. Microbiol. Infect. 18:E506-E513.
13. Zhang, R., H.W. Zhou, J.C. Cai, and G.X. Chen. 2007. Plasmid-mediated carbapenem-hydrolysing beta-lactamase KPC-2 in carbapenem-resistant Serratia marcescens isolates from Hangzhou, China. J. Antimicrob. Chemother. 59:574-576.
14. Zhang, X., X. Lu, and Z. Zong. 2012. Enterobacteriaceae producing the KPC-2 carbapenemase from hospital sewage. Diagn. Microbiol. Infect. Dis. 73:204-206.
15. Zhang, Y., J. Yang, L. Ye, Y. Luo, W. Wang, W. Zhou, Z. Cui, and L. Han. 2012. Characterization of clinical multidrug-resistant Escherichia coli and Klebsiella pneumoniae isolates, 2007-2009, China. Microb. Drug Resist. 18:465-470.