메뉴 건너뛰기




Volumn 201, Issue , 2014, Pages 215-225

Vemurafenib

Author keywords

BRAF inhibitor; BRAF mutation; Melanoma; Vemurafenib

Indexed keywords

B RAF KINASE; CAFFEINE; DACARBAZINE; DEXTROMETHORPHAN; LACTATE DEHYDROGENASE; MIDAZOLAM; MITOGEN ACTIVATED PROTEIN KINASE; OXIDOREDUCTASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN S100B; VEMURAFENIB; WARFARIN; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; SULFONAMIDE;

EID: 84905123422     PISSN: 00800015     EISSN: 21976767     Source Type: Book Series    
DOI: 10.1007/978-3-642-54490-3_13     Document Type: Article
Times cited : (31)

References (36)
  • 1
    • 84887991814 scopus 로고    scopus 로고
    • S100B and lactate dehydrogenase as response and progression markers during treatment with vemurafenib in patients with advanced melanoma
    • Epub ahead of print
    • Abusaif S, Jradi Z, Held L et al (2013) S100B and lactate dehydrogenase as response and progression markers during treatment with vemurafenib in patients with advanced melanoma. Melanoma Res 2013, Epub ahead of print.
    • (2013) Melanoma Res 2013
    • Abusaif, S.1    Jradi, Z.2    Held, L.3
  • 2
    • 74949143594 scopus 로고    scopus 로고
    • Final version of 2009 AJCC melanoma staging and classification
    • Balch CM, Gershenwald JE, Soong SJ et al (2009) Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 27: 6199-6206.
    • (2009) J Clin Oncol , vol.27 , pp. 6199-6206
    • Balch, C.M.1    Gershenwald, J.E.2    Soong, S.J.3
  • 3
    • 77956513286 scopus 로고    scopus 로고
    • Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
    • Bollag G, Hirth P, Tsai J et al (2010) Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature 467: 596-599.
    • (2010) Nature , vol.467 , pp. 596-599
    • Bollag, G.1    Hirth, P.2    Tsai, J.3
  • 5
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman PB, Hauschild A, Robert C et al (2011) Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 364: 2507-2516.
    • (2011) N Engl J Med , vol.364 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 6
    • 84865068182 scopus 로고    scopus 로고
    • Updated overall survival (OS) results for BRIM-3, a phase III randomized, open-label, multicenter trial comparing BRAF inhibitor vemurafenib (vem) with dacarbazine (DTIC) in previously untreated patients with BRAFV600E-mutated melanoma
    • Chapman PB, Hauschild A, Robert C et al (2012) Updated overall survival (OS) results for BRIM-3, a phase III randomized, open-label, multicenter trial comparing BRAF inhibitor vemurafenib (vem) with dacarbazine (DTIC) in previously untreated patients with BRAFV600E-mutated melanoma. J Clin Oncol 30: 8502.
    • (2012) J Clin Oncol , vol.30 , pp. 8502
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 7
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies H, Bignell GR, Cox C et al (2002) Mutations of the BRAF gene in human cancer. Nature 417: 949-954.
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1    Bignell, G.R.2    Cox, C.3
  • 9
    • 33644618944 scopus 로고    scopus 로고
    • Malignant melanoma: Classification and staging of malignant melanoma
    • Eigentler TK, Garbe C (2006) Malignant melanoma: classification and staging of malignant melanoma. Front Radiat Ther Oncol 39: 149-158.
    • (2006) Front Radiat Ther Oncol , vol.39 , pp. 149-158
    • Eigentler, T.K.1    Garbe, C.2
  • 12
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • Flaherty KT, Puzanov I, Kim KB et al (2010) Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 363: 809-819.
    • (2010) N Engl J Med , vol.363 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 13
    • 84866595717 scopus 로고    scopus 로고
    • A patient with BRAF V600E lung adenocarcinoma responding to vemurafenib
    • Gautschi O, Pauli C, Strobel K et al (2012) A patient with BRAF V600E lung adenocarcinoma responding to vemurafenib. J Thorac Oncol 7: e23-e24.
    • (2012) J Thorac Oncol , vol.7 , pp. 23-24
    • Gautschi, O.1    Pauli, C.2    Strobel, K.3
  • 15
    • 33947101019 scopus 로고    scopus 로고
    • Patterns of somatic mutation in human cancer genomes
    • Greenman C, Stephens P, Smith R et al (2007) Patterns of somatic mutation in human cancer genomes. Nature 446: 153-158.
    • (2007) Nature , vol.446 , pp. 153-158
    • Greenman, C.1    Stephens, P.2    Smith, R.3
  • 16
    • 0032968036 scopus 로고    scopus 로고
    • S100B protein detection in serum is a significant prognostic factor in metastatic melanoma
    • Hauschild A, Engel G, Brenner W et al (1999) S100B protein detection in serum is a significant prognostic factor in metastatic melanoma. Oncology 56: 338-344.
    • (1999) Oncology , vol.56 , pp. 338-344
    • Hauschild, A.1    Engel, G.2    Brenner, W.3
  • 18
    • 84879177690 scopus 로고    scopus 로고
    • Clinical responses to vemurafenib in patients with metastatic papillary thyroid cancer harboring BRAF(V600E) mutation
    • Kim KB, Cabanillas ME, Lazar AJ et al (2013) Clinical responses to vemurafenib in patients with metastatic papillary thyroid cancer harboring BRAF(V600E) mutation. Thyroid 23: 1277-1283.
    • (2013) Thyroid , vol.23 , pp. 1277-1283
    • Kim, K.B.1    Cabanillas, M.E.2    Lazar, A.J.3
  • 19
    • 78649723255 scopus 로고    scopus 로고
    • PLX4032 in metastatic colorectal cancer patients with mutant BRAF tumours
    • Kopetz S, Desai J, Chan E et al (2010) PLX4032 in metastatic colorectal cancer patients with mutant BRAF tumours. J Clin Oncol 28: 3534.
    • (2010) J Clin Oncol , vol.28 , pp. 3534
    • Kopetz, S.1    Desai, J.2    Chan, E.3
  • 20
    • 84873360893 scopus 로고    scopus 로고
    • Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents
    • Mao M, Tian F, Mariadason JM et al (2013) Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents. Clin Cancer Res 19: 657-667.
    • (2013) Clin Cancer Res , vol.19 , pp. 657-667
    • Mao, M.1    Tian, F.2    Mariadason, J.M.3
  • 22
    • 84862908526 scopus 로고    scopus 로고
    • RAS mutations are associated with the development of cutaneous squamous cell tumours in patients treated with RAF inhibitors
    • Oberholzer PA, Kee D, Dziunycz P et al (2012) RAS mutations are associated with the development of cutaneous squamous cell tumours in patients treated with RAF inhibitors. J Clin Oncol 30: 316-321.
    • (2012) J Clin Oncol , vol.30 , pp. 316-321
    • Oberholzer, P.A.1    Kee, D.2    Dziunycz, P.3
  • 23
    • 84875340204 scopus 로고    scopus 로고
    • Low-dose vemurafenib induces complete remission in a case of hairy-cell leukaemia with a V600E mutation
    • Peyrade F, Re D, Ginet C et al (2013) Low-dose vemurafenib induces complete remission in a case of hairy-cell leukaemia with a V600E mutation. Haematologica 98: e20-e22.
    • (2013) Haematologica , vol.98 , pp. 20-22
    • Peyrade, F.1    Re, D.2    Ginet, C.3
  • 24
    • 0034762203 scopus 로고    scopus 로고
    • The Raf/MEK/ERK pathway: New concepts of activation
    • Peyssonnaux C, Eychene A (2001) The Raf/MEK/ERK pathway: new concepts of activation. Biol Cell 93: 53-62.
    • (2001) Biol Cell , vol.93 , pp. 53-62
    • Peyssonnaux, C.1    Eychene, A.2
  • 25
    • 79951869389 scopus 로고    scopus 로고
    • Effectiveness of carboplatin and paclitaxel as first-and second-line treatment in 61 patients with metastatic melanoma
    • Pflugfelder A, Eigentler TK, Keim U et al (2011) Effectiveness of carboplatin and paclitaxel as first-and second-line treatment in 61 patients with metastatic melanoma. PLoS One 6: e16882.
    • (2011) PLoS One , vol.6
    • Pflugfelder, A.1    Eigentler, T.K.2    Keim, U.3
  • 26
    • 84863230465 scopus 로고    scopus 로고
    • Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
    • Prahallad A, Sun C, Huang S et al (2012) Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature 483: 100-103.
    • (2012) Nature , vol.483 , pp. 100-103
    • Prahallad, A.1    Sun, C.2    Huang, S.3
  • 27
    • 33749635119 scopus 로고    scopus 로고
    • Raf kinases: Oncogenesis and drug discovery
    • Schreck R, Rapp UR (2006) Raf kinases: oncogenesis and drug discovery. Int J Cancer 119: 2261-2271.
    • (2006) Int J Cancer , vol.119 , pp. 2261-2271
    • Schreck, R.1    Rapp, U.R.2
  • 28
    • 84878129271 scopus 로고    scopus 로고
    • Improved human bioavailability of vemurafenib, a practically insoluble drug, using an amorphous polymer-stabilized solid dispersion prepared by a solvent-controlled coprecipitation process
    • Shah N, Iyer RM, Mair HJ et al (2013) Improved human bioavailability of vemurafenib, a practically insoluble drug, using an amorphous polymer-stabilized solid dispersion prepared by a solvent-controlled coprecipitation process. J Pharm Sci 102: 967-981.
    • (2013) J Pharm Sci , vol.102 , pp. 967-981
    • Shah, N.1    Iyer, R.M.2    Mair, H.J.3
  • 29
    • 0027524767 scopus 로고
    • Prognostic factors in patients with metastatic malignant melanoma: A multivariate analysis
    • Sirott MN, Bajorin DF, Wong GY et al (1993) Prognostic factors in patients with metastatic malignant melanoma: a multivariate analysis. Cancer 72: 3091-3098.
    • (1993) Cancer , vol.72 , pp. 3091-3098
    • Sirott, M.N.1    Bajorin, D.F.2    Wong, G.Y.3
  • 30
    • 84863116743 scopus 로고    scopus 로고
    • Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib
    • Sosman JA, Kim KB, Schuchter L et al (2012) Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Engl J Med 366: 707-714.
    • (2012) N Engl J Med , vol.366 , pp. 707-714
    • Sosman, J.A.1    Kim, K.B.2    Schuchter, L.3
  • 31
    • 33646372471 scopus 로고    scopus 로고
    • BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than nonmucinous colorectal cancer
    • Tanaka H, Deng G, Matsuzaki K et al (2006) BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than nonmucinous colorectal cancer. Int J Cancer 118: 2765-2771.
    • (2006) Int J Cancer , vol.118 , pp. 2765-2771
    • Tanaka, H.1    Deng, G.2    Matsuzaki, K.3
  • 32
    • 79959293462 scopus 로고    scopus 로고
    • BRAF mutations in hairy-cell leukemia
    • Tiacci E, Trifonov V, Schiavoni G et al (2011) BRAF mutations in hairy-cell leukemia. N Engl J Med 364: 2305-2315.
    • (2011) N Engl J Med , vol.364 , pp. 2305-2315
    • Tiacci, E.1    Trifonov, V.2    Schiavoni, G.3
  • 33
    • 79952463028 scopus 로고    scopus 로고
    • Optimizing targeted therapeutic development: Analysis of a colorectal cancer patient population with the BRAF(V600E) mutation
    • Tie J, Gibbs P, Lipton L et al (2011) Optimizing targeted therapeutic development: analysis of a colorectal cancer patient population with the BRAF(V600E) mutation. Int J Cancer 128: 2075-2084.
    • (2011) Int J Cancer , vol.128 , pp. 2075-2084
    • Tie, J.1    Gibbs, P.2    Lipton, L.3
  • 35
    • 84864355514 scopus 로고    scopus 로고
    • Serum markers lactate dehydrogenase and S100B predict independently disease outcome in melanoma patients with distant metastasis
    • Weide B, Elsasser M, Buttner P et al (2012) Serum markers lactate dehydrogenase and S100B predict independently disease outcome in melanoma patients with distant metastasis. Br J Cancer 107: 422-428.
    • (2012) Br J Cancer , vol.107 , pp. 422-428
    • Weide, B.1    Elsasser, M.2    Buttner, P.3
  • 36
    • 37349131738 scopus 로고    scopus 로고
    • BRAF mutation in papillary thyroid cancer: Pathogenic role, molecular bases, and clinical implications
    • Xing M (2007) BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical implications. Endocr Rev 28: 742-762.
    • (2007) Endocr Rev , vol.28 , pp. 742-762
    • Xing, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.