Progesterone and cilostazol protect mice pancreatic islets from oxidative stress induced by hydrogen peroxide

Iranian Journal of Pharmaceutical Research

Volumn 13, Issue 3, 2014, Pages 937-944

  Ahangarpour, Akram ^a   Heidari, Hamid ^a   Mard, Seyyed Ali ^a   Hashemitabar, Mahmoud ^a   Khodadadi, Ali ^a  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cilostazol; Insulin; Islet; Progesterone

Indexed keywords

CATALASE; CILOSTAZOL; GLIBENCLAMIDE; HYDROGEN PEROXIDE; INSULIN; MALONALDEHYDE; PROGESTERONE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNORADIOMETRIC ASSAY; INSULIN RELEASE; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET;

EID: 84905104775     PISSN: 17350328     EISSN: 17266890     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Baluchnejad mojarada T and Roghani M. Chronic Oral Epigallocatechin-gallate alleviates streptozotocin-induced diabetic neuropathic hyperalgesia in rat: involvement of oxidative stress. Iran. J. Pharm. Res. (2012) 11: 1243-1253.
2. Rodrigues GR, Porawski M, Marcolin E, Kretzmann AN, Falcao Ferraz A and Richter MF. Treatment with aqueous extract fromcroton cajucara benth reduces hepatic oxidative stress in streptozotocin-diabetic rats. J. Biomed. Biotechnol. (2012) 2012: 1-7.
3. Ahmadvand H, Tavafic M and Khalatbary AR. Hepatoprotective and hypolipidemic effects of satureja khuzestanica ssential oil in alloxan-induced type 1 diabetic rats. Iran. J. Pharm. Res. (2012) 11: 1219-1226.
4. Gabriele W, Nicole A, Marta M, Antje B, Jurgen S and James FB. Peroxiredoxin III protects pancreatic beta cells from apoptosis. J. Endocrinol. (2010) 207: 163-175.
5. Vessby J, Basu S, Mohsen R, Berne C and Vessby B. Oxidative stress and antioxidant status in type 1 diabetes mellitus. J. Intern. Med. (2002) 251: 69-76.
6. Nguyen H and Syed V. Progesterone inhibits growth and induces apoptosis in cancer cells through modulation of ROS. Gynecol. Endocrinol. (2011) 27: 830-836.
7. Matsuoka A, Kizuka F, Lee L, Tamura I, Taniguchi K and Asada H. progesterone Increases Manganese Superoxide Dismutase Expression via a cAMP-Dependent Signaling Mediated by Noncanonical Wnt5a Pathway in Human Endometrial Stromal Cells. J. Clin. Endocrinol. Metab. (2010) 95: 291-299.
8. Morrissy S, Xu B, Aguilar D, Zhang J and Chen QM. Inhibition of apoptosis by progesterone in cardiomyocytes. Aging Cell (2010) 9: 799-809.
9. Sorenson RL, Brelje TC and Roth C. Effects of steroid and lactogenic hormones on islets of Langerhans: a new hypothesis for the role of pregnancy steroids in the adaptation of islets to pregnancy. Endocrinol. (1993) 133: 2227-2234.
10. Kim KY, Shin HK, Choi JM and Hong KW. Inhibition of lipopolysaccharide-induced apoptosis by cilostazol in human umbilical vein endothelial cells. J. Pharmacol. Exp. Ther. (2002) 300: 709-715.
11. Lee WC, Chen HC, Wang CY, Lin PY, Ou TT and Chen CC. Cilostazol ameliorates nephropathy in type 1 diabetic rats involving improvement in oxidative stress and regulation of TGF-Beta and NF-kappaB. Biosci Biotechnol. Biochem. (2010) 74: 1355-1361.
12. Watanabe T, Zhang N, Liu M, Tanaka R, Mizuno Y and Urabe T. Cilostazol protects against brain white matter damage and cognitive impairment in a rat model of chronic cerebral hypoperfusion. Stroke (2006) 37: 1539-1545.
13. Agrawal NK, Maiti R, Dash D and Pandey BL. Cilostazol reduces inflammatory burden and oxidative stress in hypertensive type 2 diabetes mellitus patients. Pharmacol. Res. (2007) 56: 118-123.
14. Milani E, Nikfar S, Khorasani R, Zamani MJ and Abdollahi M. Reduction of diabetes-induced oxidative stress by phosphodiesterase inhibitors in rats. Comp. Biochem. Physiol. C Toxicol. Pharmacol. (2005) 140: 251-255.
15. Lacy PE and Kostianovsky M. Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes (1967) 16: 35-39
16. Quesada I, Todorova MG, Beltrá M, Carneiro EM, Nadal A and Soria B. Glucose induces opposite intracellular Ca2+ concentration oscillatory patterns in identified alpha- and beta-cells within intact human islets of Langerhans. Diabetes (2006) 55: 2463-2469.
17. Jeffrey DC, Stacey BD, Kathryn LC, Runpei Wu and Craig SN. A Practical Guide to Rodent Islet Isolation and Assessment. Biol. Proced. Online (2009) 11: 3-29.
18. Xiong FL, Sun XH, Gan L, Yang XL and Xu HB. Puerarin protects rat pancreatic islets from damage by hydrogen peroxide. Eur. J. Pharmacol. (2006) 529: 1-7.
19. Irem N, Mamdouh H, Michelle E and Gladys T. The role of pregnancy hormones in the regulation of Pdx-1 expression. Mol. Cell Endocrinol. (2005) 233: 1-13.
20. Park SY, Bae JU, Hong KW and Kim CD. HO-1 Induced by Cilostazol Protects Against TNF-α associated Cytotoxicity via a PPAR-γ-dependent Pathway in Human Endothelial Cells. Korean J. Physiol. Pharmacol. (2011) 15: 83-88.
21. Hargrove DM, Nardone NA, Persson LM, Andrews KM, Shepherd KL, Stevenson RW and Parker JC. Comparison of the glucose dependency of glucagon-like peptide-1 (7-37) and glyburide in-vitro and in-vivo. Metabolism (1996) 45: 404-409.
22. Armanna B, Hansona MS, Hatcha E, Steffena A and Fernandez LA. Quantification of Basal and Stimulated ROS Levels as Predictors of Islet Potency and Function. Am. J. Transplant (2007) 7: 38-47.
23. Clairborne A. Catalase Activity. In: Greenwald RA. (ed.) Handbook of Methods for Oxygen Radical Research. Boca Raton, Florida: CRC Press (1985) 283-284.
24. Suttle NF. Copper deficiency in ruminants; recent developments. Vet. Rec. (1986) 119: 519-522.
25. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. (1976) 72: 248-254.
26. Kuchmerovs'ka TM, Donchenko HV, Tykhonenko TM, Huzyk MM, Stavniichuk RV and Klymenko AP. Nicotinamide influence on pancreatic cells viability. Ukr. Biokhim. Zh. (2012) 84: 81-88.
27. Shao J, Qiao L and Friedman JE. Prolactin, progesterone, and dexamethasone coordinately and adversely regulate glucokinase and cAMP/PDE cascades in MIN6 β-cells. Am. J. Physiol. Endocrinol. Metab. (2004) 286: 304-310.
28. Howell SL, Tyhurst M and Green IC. Direct effects of progesterone on rat islets of Langerhans in-vivo and in tissue culture. Diabetologia. (1977) 13: 579-583.
29. Jermendy A, Toschi E, Aye T, Koh A, Sharma A and Bonner-Weir S. Rat neonatal beta cells lack the specialized metabolic phenotype of mature beta cells. Diabetologia. (2011) 54: 594-604.
30. Evans JL, Goldfine ID, Maddux BA and Grodsky GM. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr. Rev. (2002) 23: 599-622.
31. Karunakaran U and Park KG. A Systematic Review of Oxidative Stress and Safety of Antioxidants in Diabetes: Focus on Islets and Their Defense. Diabetes Metab. J. (2013) 37: 106-112.
32. Zhu HQ, Gao Y, Wang JZ, Pan SH, Jiang HC and Dai WJ. Pretreatment with Bilirubin Protects Islet against Oxidative Injury During Isolation and Purification. Transplant Proc. (2011) 43: 1810-1814.
33. Suarez-Pinzon WL, Strynadka K and Rabinovitch A. Destruction of rat pancreatic islet beta-cells by cytokines involves the production of cytotoxic aldehydes. Endocrinol. (1996): 137: 5290-5296.
34. Rabinovitch A, Suarez-Pinzon WL, Strynadka K, Lakey JR and Rajotte RV. Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production. J. Clin. Endocrinol. Metab. (1996) 81: 3197-3202
35. Duprez J, Roma LP, Close A-F and Jonas J-C. Protective antioxidant and antiapoptotic effects of zncl2 in rat pancreatic islets cultured in low and high glucose concentrations. PLoS ONE. (2012) 7: 46831.
36. Markus T, Stephan L, Rex M and Sigurd L. Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species. Diabetes (1998) 47: 1578-1585.
37. Lortz S, Tiedge M, Nachtwey T, Karlsen A.E, Nerup J and Lenzen S. Protection of insulin-producing rinm5f cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes. Diabetes (2000) 49: 1123-1130.