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Volumn 2014, Issue 4, 2014, Pages 68-72

A role of glutamate decarboxylase in Alzheimer's disease

Author keywords

Alzheimer's disease; Neurochemistry

Indexed keywords

CEREBELLUM TISSUE PROTEIN; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE 1; GLUTAMATE DECARBOXYLASE 2; ISOENZYME;

EID: 84905092194     PISSN: 19977298     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (25)
  • 1
    • 0017858442 scopus 로고
    • Inhibition of different molecular forms of brain glutamic acid decarboxylase with ATP
    • Turský T., Lassánová M. Inhibition of different molecular forms of brain glutamic acid decarboxylase with ATP. J Neurochem 1978; 30: 4: 903-905.
    • (1978) J Neurochem , vol.30 , Issue.4 , pp. 903-905
    • Turský, T.1    Lassánová, M.2
  • 2
    • 0025816520 scopus 로고
    • The structural and functional heterogeneity of glutamic acid decarboxylase: A review
    • Erlander M.G., Tobin A.J. The structural and functional heterogeneity of glutamic acid decarboxylase: a review. Neurochem Res 1991; 16: 3: 215-226.
    • (1991) Neurochem Res , vol.16 , Issue.3 , pp. 215-226
    • Erlander, M.G.1    Tobin, A.J.2
  • 3
    • 0033607157 scopus 로고    scopus 로고
    • The role of the synthetic enzyme in the control of neuronal gamma-aminobutyric acid release
    • Tian N., Petersen C., Kash S. et al. The role of the synthetic enzyme in the control of neuronal gamma-aminobutyric acid release. Proc Natl Acad Sci USA 1999; 96: 12911-12916.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12911-12916
    • Tian, N.1    Petersen, C.2    Kash, S.3
  • 4
    • 46249093626 scopus 로고    scopus 로고
    • Post-translational regulation of L-glutamic acid decarboxylase in the brain
    • Wei J., Wu J.-Y. Post-translational regulation of L-glutamic acid decarboxylase in the brain. Neurochem Res 2008; 33: 1459-1465.
    • (2008) Neurochem Res , vol.33 , pp. 1459-1465
    • Wei, J.1    Wu, J.-Y.2
  • 5
    • 34247249781 scopus 로고    scopus 로고
    • GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop
    • Fenalti G., Law R.H., Buckle A.M. et al. GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nat Struct Mol Biol 2007; 14: 280-286.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 280-286
    • Fenalti, G.1    Law, R.H.2    Buckle, A.M.3
  • 6
    • 0026027134 scopus 로고
    • Two forms of the aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distribution and cofactor interaction
    • Kaufman D.L., Houser C.R., Tobin A. Two forms of the aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distribution and cofactor interaction. J Neurochem 1991; 56: 720-723.
    • (1991) J Neurochem , vol.56 , pp. 720-723
    • Kaufman, D.L.1    Houser, C.R.2    Tobin, A.3
  • 7
    • 0036717789 scopus 로고    scopus 로고
    • Is there more to GABA than synaptic inhibition?
    • Owens D., Kriegstein A. Is there more to GABA than synaptic inhibition? Nat Rev Neurosci 2002; 3: 715-727.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 715-727
    • Owens, D.1    Kriegstein, A.2
  • 8
    • 0030600546 scopus 로고    scopus 로고
    • Mice lacking the 65kDa isoform of glutamic acid decarboxylase maintain normal levels of and GABA in their brains but are susceptible to seizures
    • Asada H., Kawamura Y., Maruyama K. Mice lacking the 65kDa isoform of glutamic acid decarboxylase maintain normal levels of and GABA in their brains but are susceptible to seizures. Biochem Biophys Res Commun 1996; 229: 891-895.
    • (1996) Biochem Biophys Res Commun , vol.229 , pp. 891-895
    • Asada, H.1    Kawamura, Y.2    Maruyama, K.3
  • 9
    • 12644278303 scopus 로고    scopus 로고
    • Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase
    • Asada H., Kawamura Y., Maruyama K. Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci USA 1997; 94: 12: 6496-6499.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.12 , pp. 6496-6499
    • Asada, H.1    Kawamura, Y.2    Maruyama, K.3
  • 10
    • 84879879175 scopus 로고    scopus 로고
    • Altered synapses and gliotransmission in Alzheimer's disease and AD model mice
    • Mitew S., Kirkcaldie M.T., Dickson T.C., Vickers J.C. Altered synapses and gliotransmission in Alzheimer's disease and AD model mice. Neurobiol Aging 2013; 34: 10: 2341-2351.
    • (2013) Neurobiol Aging , vol.34 , Issue.10 , pp. 2341-2351
    • Mitew, S.1    Kirkcaldie, M.T.2    Dickson, T.C.3    Vickers, J.C.4
  • 11
    • 84859390704 scopus 로고    scopus 로고
    • Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model
    • Krantic S., Isorce N., Mechawar N. et al. Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model. J Alzheimers Dis 2012; 29: 2: 293-308.
    • (2012) J Alzheimers Dis , vol.29 , Issue.2 , pp. 293-308
    • Krantic, S.1    Isorce, N.2    Mechawar, N.3
  • 12
    • 0016400039 scopus 로고
    • Brain-decarboxylase activities as indices of pathological change in senile dementia
    • Bowen D.M., White P., Flack R.H. et al. Brain-decarboxylase activities as indices of pathological change in senile dementia. Lancet 1974; 1: 7869: 1247-1249.
    • (1974) Lancet , vol.1 , Issue.7869 , pp. 1247-1249
    • Bowen, D.M.1    White, P.2    Flack, R.H.3
  • 13
    • 0025011401 scopus 로고
    • Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementias
    • Yates C.M., Butterworth J., Tennant M.C., Gordon A. Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementias. J Neurochem 1990; 55: 5: 1624-1630.
    • (1990) J Neurochem , vol.55 , Issue.5 , pp. 1624-1630
    • Yates, C.M.1    Butterworth, J.2    Tennant, M.C.3    Gordon, A.4
  • 14
    • 0021821862 scopus 로고
    • Brain glutamate decarboxylase in Parkinson's disease with particular reference to a premortem severity index
    • Monfort J.C., Javoy-Agid F., Hauw J.J. et al. Brain glutamate decarboxylase in Parkinson's disease with particular reference to a premortem severity index. Brain 1985; 108: 2: 301-313.
    • (1985) Brain , vol.108 , Issue.2 , pp. 301-313
    • Monfort, J.C.1    Javoy-Agid, F.2    Hauw, J.J.3
  • 15
    • 0023880380 scopus 로고
    • Loss of cortical GABA uptake sites in Alzheimer's disease
    • Simpson M.D., Cross A.J., Slater P., Deakin J.F. Loss of cortical GABA uptake sites in Alzheimer's disease. J Neural Transm 1988; 71: 3: 219-226.
    • (1988) J Neural Transm , vol.71 , Issue.3 , pp. 219-226
    • Simpson, M.D.1    Cross, A.J.2    Slater, P.3    Deakin, J.F.4
  • 16
    • 84856941356 scopus 로고    scopus 로고
    • The cerebellum and neuropsychological functioning: A critical review
    • O'Halloran C.J., Kinsella G.J., Storey E. The cerebellum and neuropsychological functioning: a critical review. J Clin Exp Neuropsychol 2012; 34: 1: 35-56.
    • (2012) J Clin Exp Neuropsychol , vol.34 , Issue.1 , pp. 35-56
    • O'Halloran, C.J.1    Kinsella, G.J.2    Storey, E.3
  • 17
    • 84868671162 scopus 로고    scopus 로고
    • The cerebellum and neuropsychiatric disorders
    • Villanueva R. The cerebellum and neuropsychiatric disorders. Psychiatry Res 2012; 198: 3: 527-532.
    • (2012) Psychiatry Res , vol.198 , Issue.3 , pp. 527-532
    • Villanueva, R.1
  • 18
    • 84863297423 scopus 로고    scopus 로고
    • Calpain cleavage of brain glutamic acid decarboxylase 65 is pathological and impairs GABA neurotransmission
    • Buddhala C., Suarez M., Modi J. et al. Calpain cleavage of brain glutamic acid decarboxylase 65 is pathological and impairs GABA neurotransmission. PLoS One 2012; 7: 3: 33002.
    • (2012) PLoS One , vol.7 , Issue.3 , pp. 33002
    • Buddhala, C.1    Suarez, M.2    Modi, J.3
  • 19
    • 0028929053 scopus 로고
    • Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylase
    • Dirkx R. Jr., Thomas A., Li L. et al. Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylase. J Biol Chem 1995; 270: 2241-2246.
    • (1995) J Biol Chem , vol.270 , pp. 2241-2246
    • Dirkx Jr., R.1    Thomas, A.2    Li, L.3
  • 20
    • 0033601230 scopus 로고    scopus 로고
    • The hydrophilic isoform of glutamate decarboxylase, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform
    • Kanaani J., Lissin D., Kash S.F., Baekkeskov S. The hydrophilic isoform of glutamate decarboxylase, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform. J Biol Chem 1999; 274: 52: 37200-37209.
    • (1999) J Biol Chem , vol.274 , Issue.52 , pp. 37200-37209
    • Kanaani, J.1    Lissin, D.2    Kash, S.F.3    Baekkeskov, S.4
  • 21
    • 0023865065 scopus 로고
    • A post-mortem study of noradrenergic, serotonergic and GABAergic neurons in Alzheimer's disease
    • Reinikainen K.J., Paljärvi L., Huuskonen M. et al. A post-mortem study of noradrenergic, serotonergic and GABAergic neurons in Alzheimer's disease. J Neurol Sci 1988; 84: 1: 101-116.
    • (1988) J Neurol Sci , vol.84 , Issue.1 , pp. 101-116
    • Reinikainen, K.J.1    Paljärvi, L.2    Huuskonen, M.3
  • 22
    • 0031784321 scopus 로고    scopus 로고
    • Striatal expression of glutamic acid decarboxylase gene in Alzheimer's disease
    • Boissière F., Faucheux B., Duyckaerts C. et al. Striatal expression of glutamic acid decarboxylase gene in Alzheimer's disease. J Neurochem 1998; 71: 2: 767-774.
    • (1998) J Neurochem , vol.71 , Issue.2 , pp. 767-774
    • Boissière, F.1    Faucheux, B.2    Duyckaerts, C.3
  • 23
    • 84886631402 scopus 로고
    • Neurotransmitter enzyme abnormalities in senile dementia. Choline acetyltransferase and glutamic acid decarboxylase activities in necropsy brain tissue
    • Perry E.K., Gibson P.H., Blessed G. et al. Neurotransmitter enzyme abnormalities in senile dementia. Choline acetyltransferase and glutamic acid decarboxylase activities in necropsy brain tissue. J Neurol Sci 1977; 34: 2: 247-265.
    • (1977) J Neurol Sci , vol.34 , Issue.2 , pp. 247-265
    • Perry, E.K.1    Gibson, P.H.2    Blessed, G.3
  • 24
    • 0036307527 scopus 로고    scopus 로고
    • Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients
    • Gluck M.R., Thomas R.G., Davis K.L., Haroutunian V. Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. Am J Psychiatry 2002; 159: 7: 1165-11673.
    • (2002) Am J Psychiatry , vol.159 , Issue.7 , pp. 1165-11673
    • Gluck, M.R.1    Thomas, R.G.2    Davis, K.L.3    Haroutunian, V.4
  • 25
    • 84873651092 scopus 로고    scopus 로고
    • GABAT immunostaining in human brain and apparent loss in Alzheimer's disease
    • Schwab C., Yu S., Wong W. et al. GABAT immunostaining in human brain and apparent loss in Alzheimer's disease. J Alzheimers Dis 2013; 33: 4: 1073-1088.
    • (2013) J Alzheimers Dis , vol.33 , Issue.4 , pp. 1073-1088
    • Schwab, C.1    Yu, S.2    Wong, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.