Telmisartan inhibits the proinflammatory effects of homocysteine on human endothelial cells through activation of the peroxisome proliferator-activated receptor-δ pathway

International Journal of Molecular Medicine

Volumn 34, Issue 3, 2014, Pages 828-834

  Xu, Shanghua ^a   Song, Huanhuan ^b   Huang, Maozhi ^a   Wang, Kefeng ^c   Xu, Changsheng ^d   Xie, Liangdi ^d  

^a FUJIAN MEDICAL UNIVERSITY   (China)

^b HENAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c Second Hospital Xi'An Medical School   (China)

^d Fujian Hypertension Institute   (China)

Author keywords

Homocysteine; Human umbilical vein endothelial cells; Inflammation; Peroxisome proliferator activated receptor ; Telmisartan

Indexed keywords

3 [(4 ANILINO 2 METHOXYPHENYL)SULFAMOYL] 2 THENOIC ACID METHYL ESTER; HOMOCYSTEINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ANTAGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA ANTAGONIST; PYRROLIDINE DITHIOCARBAMATE; TELMISARTAN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; [4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; AUTACOID; BENZIMIDAZOLE DERIVATIVE; BENZOIC ACID DERIVATIVE; THIAZOLE DERIVATIVE;

ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; ENDOTHELIUM CELL; HL 60 CELL LINE; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; INFLAMMATORY DISEASE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; WESTERN BLOTTING; AGONISTS; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

BENZIMIDAZOLES; BENZOATES; CHEMOKINE CCL2; GENE EXPRESSION REGULATION; HL-60 CELLS; HOMOCYSTEINE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; NF-KAPPA B; PPAR DELTA; PROTEIN TRANSPORT; RNA, MESSENGER; SIGNAL TRANSDUCTION; THIAZOLES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84905023351     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1834     Document Type: Article

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