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Volumn 27, Issue 8, 2014, Pages 775-783

Conversion to mammalian target of rapamycin inhibitors increases risk of de novo donor-specific antibodies

Author keywords

Antibody mediated rejection; donor specific HLA antibodies; kidney transplantation; mTOR inhibitors

Indexed keywords

ANTIBODY; AZATHIOPRINE; CREATININE; CYCLOSPORIN; DONOR SPECIFIC ANTIBODY; EVEROLIMUS; HLA ANTIBODY; HLA DQB1 ANTIGEN; INTERLEUKIN 2 RECEPTOR; PREDNISONE; RAPAMYCIN; TACROLIMUS; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG; ALLOANTIBODY; CALCINEURIN INHIBITOR; HLA DQ ANTIGEN; HLA-DQB1 ANTIGEN; TARGET OF RAPAMYCIN KINASE;

EID: 84905015677     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12330     Document Type: Article
Times cited : (49)

References (34)
  • 1
    • 79953250784 scopus 로고    scopus 로고
    • Chronic calcineurin inhibitor nephrotoxicity-lest we forget
    • Chapman JR,. Chronic calcineurin inhibitor nephrotoxicity-lest we forget. Am J Transplant 2011; 11: 693.
    • (2011) Am J Transplant , vol.11 , pp. 693
    • Chapman, J.R.1
  • 2
    • 59649126728 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial
    • Schena FP, Pascoe MD, Alberu J, et al,. Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. Transplantation 2009; 87: 233.
    • (2009) Transplantation , vol.87 , pp. 233
    • Schena, F.P.1    Pascoe, M.D.2    Alberu, J.3
  • 3
    • 43749098555 scopus 로고    scopus 로고
    • Early, abrupt conversion of de novo renal transplant patients from cyclosporine to everolimus: Results of a pilot study
    • Holdaas H, Bentdal O, Pfeffer P, Mjornstedt L, Solbu D, Midtvedt K,. Early, abrupt conversion of de novo renal transplant patients from cyclosporine to everolimus: results of a pilot study. Clin Transplant 2008; 22: 366.
    • (2008) Clin Transplant , vol.22 , pp. 366
    • Holdaas, H.1    Bentdal, O.2    Pfeffer, P.3    Mjornstedt, L.4    Solbu, D.5    Midtvedt, K.6
  • 4
    • 79952361568 scopus 로고    scopus 로고
    • Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: An open-label, randomised, controlled trial
    • Budde K, Becker T, Arns W, et al,. Everolimus-based, calcineurin- inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial. Lancet 2011; 377: 837.
    • (2011) Lancet , vol.377 , pp. 837
    • Budde, K.1    Becker, T.2    Arns, W.3
  • 5
    • 79953243656 scopus 로고    scopus 로고
    • Mycophenolate mofetil-based immunosuppression with sirolimus in renal transplantation: A randomized, controlled Spare-the-Nephron trial
    • Weir MR, Mulgaonkar S, Chan L, et al,. Mycophenolate mofetil-based immunosuppression with sirolimus in renal transplantation: a randomized, controlled Spare-the-Nephron trial. Kidney Int 2011; 79: 897.
    • (2011) Kidney Int , vol.79 , pp. 897
    • Weir, M.R.1    Mulgaonkar, S.2    Chan, L.3
  • 6
    • 65249134974 scopus 로고    scopus 로고
    • Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: Concept study
    • Lebranchu Y, Thierry A, Toupance O, et al,. Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: concept study. Am J Transplant 2009; 9: 1115.
    • (2009) Am J Transplant , vol.9 , pp. 1115
    • Lebranchu, Y.1    Thierry, A.2    Toupance, O.3
  • 7
    • 80051798081 scopus 로고    scopus 로고
    • Conversion of long-term kidney transplant recipients from calcineurin inhibitor therapy to everolimus: A randomized, multicenter, 24-month study
    • Holdaas H, Rostaing L, Seron D, et al,. Conversion of long-term kidney transplant recipients from calcineurin inhibitor therapy to everolimus: a randomized, multicenter, 24-month study. Transplantation 2011; 92: 410.
    • (2011) Transplantation , vol.92 , pp. 410
    • Holdaas, H.1    Rostaing, L.2    Seron, D.3
  • 8
    • 34047236016 scopus 로고    scopus 로고
    • Antibody-mediated renal allograft rejection: Diagnosis and pathogenesis
    • Colvin RB,. Antibody-mediated renal allograft rejection: diagnosis and pathogenesis. J Am Soc Nephrol 2007; 18: 1046.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1046
    • Colvin, R.B.1
  • 9
    • 0035868344 scopus 로고    scopus 로고
    • Acute humoral rejection in renal allograft recipients: I. Incidence, serology and clinical characteristics
    • Crespo M, Pascual M, Tolkoff-Rubin N, et al,. Acute humoral rejection in renal allograft recipients: I. Incidence, serology and clinical characteristics. Transplantation 2001; 71: 652.
    • (2001) Transplantation , vol.71 , pp. 652
    • Crespo, M.1    Pascual, M.2    Tolkoff-Rubin, N.3
  • 10
    • 0036191890 scopus 로고    scopus 로고
    • Acute humoral rejection in kidney transplantation: II. Morphology, immunopathology, and pathologic classification
    • Mauiyyedi S, Crespo M, Collins AB, et al,. Acute humoral rejection in kidney transplantation: II. Morphology, immunopathology, and pathologic classification. J Am Soc Nephrol 2002; 13: 779.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 779
    • Mauiyyedi, S.1    Crespo, M.2    Collins, A.B.3
  • 11
    • 0037446624 scopus 로고    scopus 로고
    • Posttransplantation production of donor HLA-specific antibodies as a predictor of renal transplant outcome
    • Worthington JE, Martin S, Al-Husseini DM, Dyer PA, Johnson RW,. Posttransplantation production of donor HLA-specific antibodies as a predictor of renal transplant outcome. Transplantation 2003; 75: 1034.
    • (2003) Transplantation , vol.75 , pp. 1034
    • Worthington, J.E.1    Martin, S.2    Al-Husseini, D.M.3    Dyer, P.A.4    Johnson, R.W.5
  • 12
    • 33947579518 scopus 로고    scopus 로고
    • Extremely high association between appearance of HLA antibodies and failure of kidney grafts in a five-year longitudinal study
    • Mao Q, Terasaki PI, Cai J, et al,. Extremely high association between appearance of HLA antibodies and failure of kidney grafts in a five-year longitudinal study. Am J Transplant 2007; 7: 864.
    • (2007) Am J Transplant , vol.7 , pp. 864
    • Mao, Q.1    Terasaki, P.I.2    Cai, J.3
  • 13
    • 67649574165 scopus 로고    scopus 로고
    • Anti-human leukocyte antigen and donor-specific antibodies detected by luminex posttransplant serve as biomarkers for chronic rejection of renal allografts
    • Lachmann N, Terasaki PI, Budde K, et al,. Anti-human leukocyte antigen and donor-specific antibodies detected by luminex posttransplant serve as biomarkers for chronic rejection of renal allografts. Transplantation 2009; 87: 1505.
    • (2009) Transplantation , vol.87 , pp. 1505
    • Lachmann, N.1    Terasaki, P.I.2    Budde, K.3
  • 14
    • 70349112303 scopus 로고    scopus 로고
    • HLA-specific antibodies developed in the first year posttransplant are predictive of chronic rejection and renal graft loss
    • Lee PC, Zhu L, Terasaki PI, Everly MJ,. HLA-specific antibodies developed in the first year posttransplant are predictive of chronic rejection and renal graft loss. Transplantation 2009; 88: 568.
    • (2009) Transplantation , vol.88 , pp. 568
    • Lee, P.C.1    Zhu, L.2    Terasaki, P.I.3    Everly, M.J.4
  • 15
    • 1442314091 scopus 로고    scopus 로고
    • Predicting kidney graft failure by HLA antibodies: A prospective trial
    • Terasaki PI, Ozawa M,. Predicting kidney graft failure by HLA antibodies: a prospective trial. Am J Transplant 2004; 4: 438.
    • (2004) Am J Transplant , vol.4 , pp. 438
    • Terasaki, P.I.1    Ozawa, M.2
  • 16
    • 25844453715 scopus 로고    scopus 로고
    • Serial ten-year follow-up of HLA and MICA antibody production prior to kidney graft failure
    • Mizutani K, Terasaki P, Rosen A, et al,. Serial ten-year follow-up of HLA and MICA antibody production prior to kidney graft failure. Am J Transplant 2005; 5: 2265.
    • (2005) Am J Transplant , vol.5 , pp. 2265
    • Mizutani, K.1    Terasaki, P.2    Rosen, A.3
  • 17
    • 79961039264 scopus 로고    scopus 로고
    • Efficacy and safety of early cyclosporine conversion to sirolimus with continued MMF-four-year results of the Postconcept study
    • Lebranchu Y, Thierry A, Thervet E, et al,. Efficacy and safety of early cyclosporine conversion to sirolimus with continued MMF-four-year results of the Postconcept study. Am J Transplant 2011; 11: 1665.
    • (2011) Am J Transplant , vol.11 , pp. 1665
    • Lebranchu, Y.1    Thierry, A.2    Thervet, E.3
  • 18
    • 84860431997 scopus 로고    scopus 로고
    • Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation
    • Liefeldt L, Brakemeier S, Glander P, et al,. Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation. Am J Transplant 2012; 12: 1192.
    • (2012) Am J Transplant , vol.12 , pp. 1192
    • Liefeldt, L.1    Brakemeier, S.2    Glander, P.3
  • 19
    • 84878644009 scopus 로고    scopus 로고
    • Incidence of donor-specific antibodies in kidney transplant patients following conversion to an everolimus-based calcineurin inhibitor-free regimen
    • Kamar N, Del Bello A, Congy-Jolivet N, et al,. Incidence of donor-specific antibodies in kidney transplant patients following conversion to an everolimus-based calcineurin inhibitor-free regimen. Clin Transplant 2013; 27: 455.
    • (2013) Clin Transplant , vol.27 , pp. 455
    • Kamar, N.1    Del Bello, A.2    Congy-Jolivet, N.3
  • 20
    • 40449101372 scopus 로고    scopus 로고
    • Banff 07 classification of renal allograft pathology: Updates and future directions
    • Solez K, Colvin RB, Racusen LC, et al,. Banff 07 classification of renal allograft pathology: updates and future directions. Am J Transplant 2008; 8: 753.
    • (2008) Am J Transplant , vol.8 , pp. 753
    • Solez, K.1    Colvin, R.B.2    Racusen, L.C.3
  • 21
    • 65549162646 scopus 로고    scopus 로고
    • Sirolimus in kidney transplantation indications and practical guidelines: De novo sirolimus-based therapy without calcineurin inhibitors
    • Flechner SM,. Sirolimus in kidney transplantation indications and practical guidelines: de novo sirolimus-based therapy without calcineurin inhibitors. Transplantation 2009; 87 (8 Suppl): S1.
    • (2009) Transplantation , vol.87 , Issue.8 SUPPL.
    • Flechner, S.M.1
  • 22
    • 35248844442 scopus 로고    scopus 로고
    • Sirolimus versus cyclosporine in kidney recipients receiving thymoglobulin, mycophenolate mofetil and a 6-month course of steroids
    • Buchler M, Caillard S, Barbier S, et al,. Sirolimus versus cyclosporine in kidney recipients receiving thymoglobulin, mycophenolate mofetil and a 6-month course of steroids. Am J Transplant 2007; 7: 2522.
    • (2007) Am J Transplant , vol.7 , pp. 2522
    • Buchler, M.1    Caillard, S.2    Barbier, S.3
  • 23
    • 33644678828 scopus 로고    scopus 로고
    • Comparison of sirolimus with low-dose tacrolimus versus sirolimus-based calcineurin inhibitor-free regimen in live donor renal transplantation
    • Hamdy AF, El-Agroudy AE, Bakr MA, et al,. Comparison of sirolimus with low-dose tacrolimus versus sirolimus-based calcineurin inhibitor-free regimen in live donor renal transplantation. Am J Transplant 2005; 5: 2531.
    • (2005) Am J Transplant , vol.5 , pp. 2531
    • Hamdy, A.F.1    El-Agroudy, A.E.2    Bakr, M.A.3
  • 24
    • 33744473322 scopus 로고    scopus 로고
    • Target of rapamycin inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: A systematic review and meta-analysis of randomized trials
    • Webster AC, Lee VW, Chapman JR, Craig JC,. Target of rapamycin inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: a systematic review and meta-analysis of randomized trials. Transplantation 2006; 81: 1234.
    • (2006) Transplantation , vol.81 , pp. 1234
    • Webster, A.C.1    Lee, V.W.2    Chapman, J.R.3    Craig, J.C.4
  • 25
    • 33747095113 scopus 로고    scopus 로고
    • Differences in proteinuria and graft function in de novo sirolimus-based vs. Calcineurin inhibitor-based immunosuppression in live donor kidney transplantation
    • Stephany BR, Augustine JJ, Krishnamurthi V, et al,. Differences in proteinuria and graft function in de novo sirolimus-based vs. calcineurin inhibitor-based immunosuppression in live donor kidney transplantation. Transplantation 2006; 82: 368.
    • (2006) Transplantation , vol.82 , pp. 368
    • Stephany, B.R.1    Augustine, J.J.2    Krishnamurthi, V.3
  • 26
    • 33644889043 scopus 로고    scopus 로고
    • Complete avoidance of calcineurin inhibitors in renal transplantation: A randomized trial comparing sirolimus and tacrolimus
    • Larson TS, Dean PG, Stegall MD, et al,. Complete avoidance of calcineurin inhibitors in renal transplantation: a randomized trial comparing sirolimus and tacrolimus. Am J Transplant 2006; 6: 514.
    • (2006) Am J Transplant , vol.6 , pp. 514
    • Larson, T.S.1    Dean, P.G.2    Stegall, M.D.3
  • 27
    • 37349034394 scopus 로고    scopus 로고
    • Reduced exposure to calcineurin inhibitors in renal transplantation
    • Ekberg H, Tedesco-Silva H, Demirbas A, et al,. Reduced exposure to calcineurin inhibitors in renal transplantation. N Engl J Med 2007; 357: 2562.
    • (2007) N Engl J Med , vol.357 , pp. 2562
    • Ekberg, H.1    Tedesco-Silva, H.2    Demirbas, A.3
  • 28
    • 34548593235 scopus 로고    scopus 로고
    • Calcineurin inhibitor-free immunosuppression in kidney transplantation
    • Guerra G, Srinivas TR, Meier-Kriesche HU,. Calcineurin inhibitor-free immunosuppression in kidney transplantation. Transpl Int 2007; 20: 813.
    • (2007) Transpl Int , vol.20 , pp. 813
    • Guerra, G.1    Srinivas, T.R.2    Meier-Kriesche, H.U.3
  • 29
    • 65549107868 scopus 로고    scopus 로고
    • Protocol conversion from a calcineurin inhibitor based therapy to sirolimus
    • Oberbauer R,. Protocol conversion from a calcineurin inhibitor based therapy to sirolimus. Transplantation 2009; 87 (8 Suppl): S7.
    • (2009) Transplantation , vol.87 , Issue.8 SUPPL.
    • Oberbauer, R.1
  • 30
    • 48049104898 scopus 로고    scopus 로고
    • Long-term efficacy and safety of a calcineurin inhibitor-free regimen in live-donor renal transplant recipients
    • Hamdy AF, Bakr MA, Ghoneim MA,. Long-term efficacy and safety of a calcineurin inhibitor-free regimen in live-donor renal transplant recipients. J Am Soc Nephrol 2008; 19: 1225.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1225
    • Hamdy, A.F.1    Bakr, M.A.2    Ghoneim, M.A.3
  • 31
    • 43549119111 scopus 로고    scopus 로고
    • Longitudinal testing of 266 renal allograft patients for HLA and MICA antibodies: Greenville experience
    • Ozawa M, Rebellato LM, Terasaki PI, et al,. Longitudinal testing of 266 renal allograft patients for HLA and MICA antibodies: greenville experience. Clin Transpl. 2006; 20: 265.
    • (2006) Clin Transpl , vol.20 , pp. 265
    • Ozawa, M.1    Rebellato, L.M.2    Terasaki, P.I.3
  • 32
    • 37349126592 scopus 로고    scopus 로고
    • Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR, DQ, DP epitopes
    • Duquesnoy RJ, Awadalla Y, Lomago J, et al,. Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR, DQ, DP epitopes. Transpl Immunol 2008; 18: 352.
    • (2008) Transpl Immunol , vol.18 , pp. 352
    • Duquesnoy, R.J.1    Awadalla, Y.2    Lomago, J.3
  • 33
    • 78650176424 scopus 로고    scopus 로고
    • Significant association between chronic antibody-mediated rejection and donor-specific antibodies against HLA-DRB rather than DQB in renal transplantation
    • Kobayashi T, Maruya E, Niwa M, et al,. Significant association between chronic antibody-mediated rejection and donor-specific antibodies against HLA-DRB rather than DQB in renal transplantation. Hum Immunol 2011; 72: 11.
    • (2011) Hum Immunol , vol.72 , pp. 11
    • Kobayashi, T.1    Maruya, E.2    Niwa, M.3
  • 34
    • 58149280266 scopus 로고    scopus 로고
    • Donor-specific HLA alloantibodies: Long-term impact on cardiac allograft vasculopathy and mortality after heart transplant
    • Kaczmarek I, Deutsch MA, Kauke T, et al,. Donor-specific HLA alloantibodies: long-term impact on cardiac allograft vasculopathy and mortality after heart transplant. Exp Clin Transplant 2008; 6: 229.
    • (2008) Exp Clin Transplant , vol.6 , pp. 229
    • Kaczmarek, I.1    Deutsch, M.A.2    Kauke, T.3


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