Chronic sleep loss during pregnancy as a determinant of stress: Impact on pregnancy outcome

Sleep Medicine

Volumn 15, Issue 8, 2014, Pages 853-859

  Palagini, Laura ^a   Gemignani, Angelo ^a   Banti, Susanna ^a   Manconi, Mauro ^b   Mauri, Mauro ^a   Riemann, Dieter ^c  

^a UNIVERSITY OF PISA   (Italy)

^b REGIONAL HOSPITAL OF LUGANO   (Switzerland)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Allostatic load; Insomnia; Poor sleep quality; Pregnancy outcome; Sleep loss; Stress

Indexed keywords

BIRTH WEIGHT; CASE CONTROL STUDY; CHRONIC SLEEP LOSS; CROSS-SECTIONAL STUDY; DELIVERY; ECLAMPSIA; FEMALE; FETUS GROWTH; HUMAN; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IMMUNE DEFICIENCY; INFLAMMATION; INSOMNIA; INTRAUTERINE GROWTH RETARDATION; LABOR; LONGITUDINAL STUDY; LOW BIRTH WEIGHT; MATERNAL HYPERTENSION; MORBIDITY; OBSERVATIONAL STUDY; PATHOPHYSIOLOGY; PITTSBURGH SLEEP QUALITY INDEX; PREECLAMPSIA; PREGNANCY; PREGNANCY DIABETES MELLITUS; PREGNANCY OUTCOME; PREGNANT WOMAN; PREMATURE LABOR; PRENATAL DEPRESSION; PRENATAL DISORDER; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SLEEP DEPRIVATION; SLEEP DISORDER; SLEEP PATTERN; SLEEP QUALITY; SLEEP TIME; SPONTANEOUS ABORTION; STRESS; SYSTEMATIC REVIEW; COMPLICATION; ETIOLOGY; MENTAL STRESS; PREGNANCY COMPLICATION; PSYCHOLOGY; CHRONIC DISEASE; COHORT ANALYSIS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOPATHOLOGY; LABOR STAGE; NONHUMAN;

FEMALE; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY OUTCOME; SLEEP DEPRIVATION; STRESS, PSYCHOLOGICAL;

EID: 84905013590     PISSN: 13899457     EISSN: 18785506     Source Type: Journal    
DOI: 10.1016/j.sleep.2014.02.013     Document Type: Review

References (126)

1. Sevil U., Bakici A. Identification of the physical health problems and affecting factors in pregnancy. Health Soc J 2002, 12:56-62.
2. Yanikkerem E., Altiparmak S., Karadeniz G. Review of the physical health problems experienced in pregnancy. Family and community education. Culture Res J 2006, 3:35-42.
3. Lee K.A. Alterations in sleep during pregnancy and postpartum: a review of 30 years of research. Sleep Med Rev 1998, 2:231-234.
4. Mindell J.A., Jacobson B.J. Sleep disturbances during pregnancy. J Obstet Gynecol Neonatal Nurs 2000, 29:590-597.
5. Pien G.W., Schwab R.J. Sleep disorders during pregnancy. Sleep 2004, 27:1405-1417.
6. National Sleep Foundation. Summary of Findings of the 2007 Sleep in America Poll. Available at: http://sleepfoundation.org/media-center/press-release/sleep-america-poll-summary-findings.
7. Hunter L.P., Rychnovsky J.D., Yount S.M. A selective review of maternal sleep characteristics in the postpartum period. J Obstet Gynecol Neonatal Nurs 2009, 38:60-68.
8. Kempler L., Sharpe L., Bartlett D. Sleep education during pregnancy for new mothers. BMC Pregnancy Childbirth 2012, 12:155.
9. Santiago J.R., Nolledo M.S., Kinzler W., Santiago T.V. Sleep and sleep disorders in pregnancy. Ann Intern Med 2001, 134:396-408.
10. Sahota P.K., Jain S.S., Dhand R. Sleep disorders in pregnancy. Curr Opin Pulm Med 2003, 9:477-483.
11. Bourjeily G., Ankner G., Mohsenin V. Sleep-disordered breathing in pregnancy. Clin Chest Med 2011, 32:175-189.
12. Ibrahim S., Foldvary-Schaefer N. Sleep disorders in pregnancy: implications, evaluation, and treatment. Neurol Clin 2012, 30:925-936.
13. Hertz G., Fast A., Feinsilver S.H., Albertario C.L., Schulman H., Fein A.M. Sleep in normal late pregnancy. Sleep 1992, 15:246-251.
14. Manconi M., Govoni V., De Vito A., Economou N.T., Cesnik E., Mollica G., et al. Pregnancy as a risk factor for restless legs syndrome. Sleep Med 2004, 5:305-308.
15. Parry B.L., Martinez F., Maurer E., Lopez A., Sorenson D., Meliska C. Sleep rhythms and women's mood: Part I. Menstrual cycle, pregnancy and postpartum. Sleep Med Rev 2006, 10:129-144.
16. Izci-Balserak B., Pien G.W. Sleep-disordered breathing and pregnancy: potential mechanisms and evidence for maternal and fetal morbidity. Curr Opin Pulm Med 2010, 16:574-582.
17. O'Keeffe M., St-Onge M.P. Sleep duration and disorders in pregnancy: implications for glucose metabolism and pregnancy outcomes. Int J Obes 2013, 37:765-770.
18. Okun M.L., Roberts J.M., Marsland A.L., Hall M. How disturbed sleep may be a risk factor for adverse pregnancy outcomes. Obstet Gynecol Surv 2009, 64:273-280.
19. O'Brien L.M. Sleep disruption and adverse pregnancy outcomes. BMC Pregn Childbirth 2012, 12:11.
20. August E.M., Salihu H.M., Biroscak B.J., Rahman S., Bruder K., Whiteman V.E. Systematic review on sleep disorders and obstetric outcomes: scope of current knowledge. Am J Perinatol 2012, 30:323-334.
21. Facco F.L. Sleep-disordered breathing and pregnancy. Semin Perinatol 2011, 35:335-339.
22. McEwen B.S. Sleep deprivation as a neurobiologic and physiologic stressor: allostasis and allostatic load. Metabolism 2006, 55:20-23.
23. Spiegel K., Knutson K., Leproult R., Tasali E., Van Cauter E. Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes. J Appl Physiol 2005, 99:2008-2019.
24. Mullington J.M., Haack M., Toth M., Serrador J.M., Meier-Ewert H.K. Cardiovascular, inflammatory, and metabolic consequences of sleep deprivation. Prog Cardiovasc Dis 2009, 51:294-302.
25. Gangwisch J.E., Heymsfield S.B., Boden-Albala B., Buijs R.M., Kreier F., Pickering T.G., et al. Sleep duration as a risk factor for diabetes incidence in a large U.S. sample. Sleep 2007, 30:1667-1673.
26. Spiegelhalder K., Scholtes C., Riemann D. The association between insomnia and cardiovascular diseases. Nat Sci Sleep 2010, 2:71-78.
27. Palagini L., Bruno R.M., Gemignani A., Baglioni C., Ghiadoni L., Riemann D. Sleep loss and hypertension: a systematic review. Curr Pharm Des 2013, 19:2409-2419.
28. Baglioni C., Battagliese G., Feige B., Spiegelhalder K., Nissen C., Voderholzer U., et al. Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord 2011, 135:10-19.
29. Meerlo P., Sgoifo A., Suchecki D. Restricted and disrupted sleep: effects on autonomic function, neuroendocrine stress systems and stress responsivity. Sleep Med Rev 2008, 12:197-210.
30. Han K.S., Kim L., Shim I. Stress and sleep disorder. Exp Neurobiol 2012, 21:141-150.
31. Cardwell M.S. Stress: pregnancy considerations. Obstet Gynecol Surv 2013, 68:119-129.
32. Lumley J. Defining the problem: the epidemiology of preterm birth. BJOG 2003, 110:3-7.
33. Peacock J.L., Bland J.M., Anderson H.R. Preterm delivery: effects of socioeconomic factors, psychological stress, smoking, alcohol, and caffeine. BMJ 1995, 311:531-535.
34. Sibai B.M. Risk factors, pregnancy complications, and prevention of hypertensive disorders in women with pregravid diabetes mellitus. J Matern Fetal Med 2000, 9:62-65.
35. March of Dimes. Pregnancy complications. 2006. Available at: http://www.marchofdimes.com/pregnancy/pregnancy-complications.aspx#.
36. Hollander M.H., Paarlberg K.M., Huisjes A.J. Gestational diabetes: a review of the current literature and guidelines. Obstet Gynecol Surv 2007, 62:125-136.
37. Elek S.M., Hudson D.B., Fleck M.O. Expectant parents' experience with fatigue and sleep during pregnancy. Birth 1997, 24:49-54.
38. Kizilirmak A., Timur S., Kartal B. Insomnia in pregnancy and factors related to insomnia. Scient World J 2012, 2012:197093.
39. Hutchison B.L., Stone P.R., McCowan L.M., Stewart A.W., Thompson J.M., Mitchell E.A. A postal survey of maternal sleep in late pregnancy. BMC Pregn Childbirth 2012, 12:144.
40. Karacan I., Heine W., Agnew H.W., Williams R.L., Webb W.B., Ross J.J. Characteristics of sleep patterns during late pregnancy and postpartum periods. Am J Obstet Gynecol 1968, 101:579-586.
41. Brunner D.P., Munch M., Biedermann K., Huh R., Borbely A.A. Changes in sleep and sleep electroencephalogram during pregnancy. Sleep 1994, 17:576-582.
42. Waters M.A., Lee K.A. Differences between primigravidae and multigravidae mothers in sleep disturbances, fatigue, and functional status. J Nurse Midwifery 1996, 41:364-367.
43. Baratte-Beebe K.R., Lee K. Sources of mid sleep awakenings in childbearing women. Clin Nurs Res 1999, 8:386-397.
44. Lee K.A., Zaffke M.E., McEnany G. Parity and sleep patterns during and after pregnancy. Obstet Gynecol 2000, 95:14-18.
45. Hedman C., Pohjasvaara T., Tolonen U., Suhonen-Malm A.S., Myllylä V.V. Effects of pregnancy on mothers' sleep. Sleep Med 2002, 3:37-42.
46. Greenwood K.M., Hazendonk K.M. Self-reported sleep during the third trimester of pregnancy. Behav Sleep Med 2004, 2:191-204.
47. Okun M.L., Hall M., Coussons-Read M.E. Sleep disturbances increase interleukin-6 production during pregnancy: implications for pregnancy complications. Reprod Sci 2007, 14:560-567.
48. Neau J.P., Texier B., Ingrand P. Sleep and vigilance disorders in pregnancy. Eur Neurol 2009, 62:23-29.
49. Facco F.L., Kramer J., Ho K.H., Zee P.C., Grobman W.A. Sleep disturbances in pregnancy. Obstet Gynecol 2010, 115:77-83.
50. Naud K., Ouellet A., Brown C., Pasquier J.C., Moutquin J.M. Is sleep disturbed in pregnancy?. J Obstet Gynaecol Can 2010, 32:28-34.
51. Kamysheva E., Skouteris H., Wertheim E.H., Paxton S.J., Milgrom J. A prospective investigation of the relationships among sleep quality, physical symptoms, and depressive symptoms during pregnancy. J Affect Disord 2010, 123:317-320.
52. Fernández-Alonso A.M., Trabalón-Pastor M., Chedraui P., Pérez-López F.R. Factors related to insomnia and sleepiness in the late third trimester of pregnancy. Arch Gynecol Obstet 2012, 286:55-61.
53. Dunkel Schetter C., Tanner L. Anxiety, depression and stress in pregnancy: implications for mothers, children, research, and practice. Curr Opin Psychiatry 2012, 25:141-148.
54. Bonari L., Pinto N., Ahn E., Einarson A., Steiner M., Koren G. Perinatal risks of untreated depression during pregnancy. Can J Psychiatry 2004, 49:726-735.
55. Field T., Diego M., Dieter J., Hernandez-Rief M., Schanberg S., Kuhn C., et al. Prenatal depression effects on the foetus and the newborn. Infant Behav Dev 2004, 27:216-229.
56. Field T., Diego M., Hernandez-Reif M. Prenatal depression effects on the fetus and newborn: a review. Infant Behav Dev 2006, 29:445-455.
57. Field T., Diego M., Hernandez-Reif M., Figueiredo B., Schanberg S., Kuhn C., et al. Chronic prenatal depression and neonatal outcome. Int J Neurosci 2008, 118:95-103.
58. Dayan J., Creveuil C., Marks M.N., Conroy S., Herlicoviez M., Dreyfus M., et al. Prenatal depression, prenatal anxiety, and spontaneous preterm birth: a prospective cohort study among women with early and regular care. Psychosom Med 2006, 68:938-946.
59. Li D., Liu L., Odouli R. Presence of depressive symptoms during early pregnancy and the risk of preterm delivery: a prospective cohort study. Hum Reprod 2009, 24:146-153.
60. Grote N.K., Bridge J.A., Gavin A.R., Melville J.L., Iyengar S., Katon W.J. A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction 21. Archs Gen Psychiatry 2010, 67:1012-1024.
61. Field T., Diego M., Hernandez-Reif M., Figueiredo B., Schanberg S., Kuhn C. Sleep disturbances in depressed pregnant women and their newborns. Infant Behav Dev 2007, 30:127-133.
62. DiPietro J., Novak M.F., Costigan K.A., Atella L.D., Reusing S.P. Maternal psychological distress during pregnancy in relation to child development at age two. Child Dev 2006, 77:573-587.
63. Swanson L.M., Pickett S.M., Flynn H., Armitage R. Relationships among depression, anxiety, and insomnia symptoms in perinatal women seeking mental health treatment. J Women's Health 2011, 20:553-558.
64. Jomeen J., Martin C.R. Assessment and relationship of sleep quality to depression in early pregnancy. J Reprod Infant Psychol 2007, 25:87-99.
65. Okun M.L., Kiewra K., Luther J.F., Wisniewski S.R., Wisner K.L. Sleep disturbances in depressed and nondepressed pregnant women. Depress Anxiety 2011, 28:676-685.
66. Skouteris H., Germano C., Wertheim E.H., Paxton S.J., Milgrom J. Sleep quality and depression during pregnancy: a prospective study. J Sleep Res 2008, 17:217-220.
67. Skouteris H., Wertheim E.H., Germano C., Paxton S.J., Milgrom J. Assessing sleep during pregnancy: a study across two time points examining the Pittsburgh Sleep Quality Index and associations with depressive symptoms. Women's Health Issues 2009, 19:45-51.
68. American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes Care 2009, 32:62-67.
69. Gilmartin A.B., Ural S.H., Repke J.T. Gestational diabetes mellitus. Rev Obstet Gynecol 2008, 1:129-134.
70. Qiu C., Enquobahrie D., Frederick I.O., Abetew D., Williams M.A. Glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot study. BMC Women's Health 2010, 10:17.
71. Reutrakul S., Zaidi N., Wroblewski K., Kay H.H., Ismail M., Ehrmann D.A., et al. Sleep disturbances and their relationship to glucose tolerance in pregnancy. Diabetes Care 2011, 34:2454-2457.
72. Bhattacharya D.M., Campbell S. The incidence of severe complications of preeclampsia Hypertens Pregn 2005, 24:181-190.
73. Von Dadelszen P., Menzies J., Payne B., Mage L. Predicting adverse outcomes in women with severe pre-eclampsia. Semin Perinatol 2009, 33:152-157.
74. Ekholm E.M., Polo O., Rauhala E.R., Ekblad U.U. Sleep quality in pre-eclampsia. Am J Obstet Gynecol 1992, 167:1262-1266.
75. Edwards N., Blyton C.M., Kesby G.J., Wilcox I., Sullivan C.E. Pre-eclampsia is associated with marked alterations in sleep architecture. Sleep 2000, 23:619-625.
76. Williams M.A., Miller R.S., Qiu C., Cripe S.M., Gelaye B., Enquobahrie D. Associations of early pregnancy sleep duration with trimester-specific blood pressures and hypertensive disorders in pregnancy. Sleep 2010, 33:1363-1371.
77. Evans M.L., Dick M.J., Clark A.S. Sleep during the week before labor: relationships to labor outcomes. Clin Nurs Res 1995, 4:238-249.
78. Lee K.A., Gay C.L. Sleep in late pregnancy predicts length of labor and type of delivery. Am J Obstet Gynecol 2004, 191:2041-2046.
79. Naghi I., Keypour F., Ahari S.B., Tavalai S.A., Khak M. Sleep disturbance in late pregnancy and type and duration of labour. J Obstet Gynaecol 2011, 31:489-491.
80. Wangel A.M., Molin J., Ostman M., Jernström H. Emergency cesarean sections can be predicted by markers for stress, worry and sleep disturbances in first-time mothers. Acta Obstet Gynecol Scand 2011, 90:238-244.
81. Zafarghandi N., Hadavand S., Davati A., Mohseni S.M., Kimiaiimoghadam F., Torkestani F. The effects of sleep quality and duration in late pregnancy on labor and fetal outcome. J Matern Fetal Neonatal Med 2012, 25:535-537.
82. Ananth C.V., Vintzileos A.M. Medically indicated preterm birth: recognizing the importance of the problem. Clin Perinatol 2008, 35:53-67.
83. Goldenberg R.L., Culhane J.F., Iams J.D., Romero R. Epidemiology and causes of preterm birth. Lancet 2008, 371:75-84.
84. Institute of Medicine of National Academies Consensus Report Preterm birth: causes, consequences, and prevention 2006, US National Academy of Sciences, Washington, DC.
85. Martin J.A., Kirmeyer S., Osterman M., Shepherd R.A. Born a bit too early: recent trends in late preterm births 2009, National Center for Health Statistics Data Brief, Atlanta, p. 1-8.
86. Williamson D.M., Abe K., Bean C., Ferre C., Henderson Z., Lackritz E. Current research in preterm birth. J Women's Health 2008, 17:1545-1549.
87. Chang J.J., Pien G.W., Duntley S.P., Macones G.A. Sleep deprivation during pregnancy and maternal and fetal outcomes: is there a relationship?. Sleep Med Rev 2010, 14:107-114.
88. Beebe K.R., Lee K.A. Sleep disturbance in late pregnancy and early labor. J Perinat Neonatal Nurs 2007, 21:103-108.
89. Strange L.B., Parker K.P., Moore M.L., Strickland O.L., Bliwise D.L. Disturbed sleep and preterm birth: a potential relationship?. Clin Exp Obstet Gynecol 2009, 36:166-168.
90. Samaraweera Y., Abeysena C. Maternal sleep deprivation, sedentary lifestyle and cooking smoke: risk factors for miscarriage: a case control study. Aust NZ J Obstet Gynaecol 2010, 50:352-357.
91. Okun M.L., Schetter C.D., Glynn L.M. Poor sleep quality is associated with preterm birth. Sleep 2011, 34:1493-1498.
92. Micheli K., Komninos I., Bagkeris E., Roumeliotaki T., Koutis A., Kogevinas M., et al. Sleep patterns in late pregnancy and risk of preterm birth and fetal growth restriction. Epidemiology 2011, 22. 738-4.
93. Okun M.L., Luther J.F., Wisniewski S.R., Sit D., Prairie B.A., Wisner K.L. Disturbed sleep, a novel risk factor for preterm birth?. J Women's Health 2012, 21:54-60.
94. Abeysena C., Jayawardana P., Seneviratne R. Effect of psychosocial stress and physical activity on low birth weight: a cohort study. J Obstet Gynaecol Res 2010, 36:296-303.
95. Bonzini M., Palmer K.T., Coggon D., Carugno M., Cromi A., Ferrario M.M. Shift work and pregnancy outcomes: a systematic review with meta-analysis of currently available epidemiological studies. BJOG 2011, 118:1429-1437.
96. Bateson P., Barker D., Clutton-Brock T., Deb D., D'Udine B., Foley R.A., et al. Developmental plasticity and human health. Nature 2004, 430:419-421.
97. Institute of Medicine (US) Committee on Understanding Premature Birth and Assuring Healthy Outcomes Preterm birth: causes, consequences, and prevention 2007, National Academies Press (US), Washington, DC. R.E. Behrman, S.A. Butler (Eds.).
98. Baglioni C., Riemann D. Is chronic insomnia a precursor to major depression? Epidemiological and biological findings. Curr Psychiatry Rep 2012, 14:511-518.
99. Field T., Hernandez-Reif M., Diego M., Schanberg S., Kuhn C. Stability of mood states and biochemistry across pregnancy. Infant Behav Dev 2006, 29:262-267.
100. Field T., Diego M., Hernandez-Reif M. Prenatal depression effects and interventions: a review. Infant Behav Dev 2010, 33:409-418.
101. Irwin M., Clark C., Kennedy B., Christian G.J., Ziegler M. Nocturnal catecholamines and immune function in insomniacs, depressed patients, and control subjects. Brain Behav Immun 2003, 17:365-372.
102. Cyranowski J.M., Marsland A.L., Bromberger J.T., Whiteside T.L., Chang Y., Matthews K.A. Depressive symptoms and production of proinflammatory cytokines by peripheral blood mononuclear cells stimulated in vitro. Brain Behav Immun 2007, 21:229-237.
103. Knutson K.L. Impact of sleep and sleep loss on glucose homeostasis and appetite regulation. Sleep Med Clin 2007, 2:187-197.
104. Knutson K.L., Spiegel K., Penev P., Van Cauter E. The metabolic consequences of sleep deprivation. Sleep Med Rev 2007, 11:163-178.
105. Padilha H.G., Crispim C.A., Zimberg I.Z., De-Souza D.A., Waterhouse J., Tufik S., et al. Link between sleep loss, glucose metabolism and adipokines. Braz J Med Biol Res 2011, 44:992-999.
106. Engeda J., Mezuk B., Ratliff S., Ning Y. Association between duration and quality of sleep and the risk of pre-diabetes: evidence from NHANES. Diabet Med 2013, 30:676-680.
107. McNeil J., Doucet E., Chaput J.P. Inadequate sleep as a contributor to obesity and type 2 diabetes. Can J Diabetes 2013, 37:103-108.
108. Gitau R., Fisk N.M., Glover V. Maternal stress in pregnancy and its effect on the human foetus: an overview of research findings. Stress 2001, 4:195-203.
109. Mulder E.J., Robles de Medina P.G., Huizink A.C., Van den Bergh B.R., Buitelaar J.K., Visser G.H. Prenatal maternal stress: effects on pregnancy and the (unborn) child. Early Hum Dev 2002, 70:3-14.
110. Austin M.P., Leader L.R., Reilly N. Prenatal stress, the hypothalamic-pituitary-adrenal axis, and fetal and infant neurobehaviour. Early Hum Dev 2005, 81:917-992.
111. O'Donnell K., O'Connor T.G., Glover V. Prenatal stress and neurodevelopment of the child: focus on the HPA axis and role of the placenta. Dev Neurosci 2009, 31:285-292.
112. Wadhwa P.D., Culhane J.F., Rauh V., Barve S.S., Hogan V., Sandman C.A., et al. Stress, infection and preterm birth: a biobehavioural perspective. Paediatr Perinat Epidemiol 2001, 15:17-29.
113. Wadhwa P.D., Culhane J.F., Rauh V., Barve S.S. Stress and preterm birth: neuroendocrine, immune/inflammatory, and vascular mechanisms. Matern Child Health J 2001, 5:119-125.
114. Ruiz R.J., Fullerton J., Dudley D.J. The interrelationship of maternal stress, endocrine factors and inflammation on gestational length. Obstet Gynecol Surv 2003, 58:415-428.
115. László K.D., Liu X.Q., Svensson T., Wikström A.K., Li J., Olsen J., et al. Psychosocial stress related to the loss of a close relative the year before or during pregnancy and risk of preeclampsia. Hypertension 2013, 62:183-189.
116. Spielman A.J., Caruso L.S., Glovinsky P.B. A behavioural perspective on insomnia treatment. Psychiatr Clin North Am 1987, 10:541-553.
117. Healey E.S., Kales A., Monroe L.J., Bixler E.O., Chamberlin K., Soldatos C.R. Onset of insomnia: role of life-stress events. Psychosom Med 1981, 43:439-451.
118. Haynes S.N., Adams A., Franzen M. The effects of presleep stress on sleep-onset insomnia. J Abnorm Psychol 1981, 90:601-606.
119. Rubman S, Brantley PJ, Waters WF, Jones GN, Constans JI, Findley JC. Daily stress and insomnia. In: Proceedings of the Eleventh Annual Scientific Sessions of the Society of Behavioral Medicine, Chicago, April 18-21; 1990 (abstract).
120. Morin C.M., Rodrigue S., Ivers H. Role of stress, arousal, and coping skills in primary insomnia. Psychosom Med 2003, 65:259-267.
121. Drake C., Richardson G., Roehrs T., Scofield H., Roth T. Vulnerability to stress-related sleep disturbance and hyperarousal. Sleep 2004, 27:285-291.
122. Riemann D., Spiegelhalder K., Feige B., Voderholzer U., Berger M., Perlis M., et al. The hyperarousal model of insomnia: a review of the concept and its evidence. Sleep Med Rev 2010, 14:19-31.
123. McEwen B.S., Stellar E. Stress and the individual: mechanisms leading to disease. Archs Intern Med 1993, 153:2093-2101.
124. McEwen B.S. Protective and damaging effects of stress mediators. N Engl J Med 1998, 338:171-179.
125. Duman R.S. Depression: a case of neuronal life and death?. Biol Psychiatry 2004, 56:140-145.
126. Drevets W.C. Prefrontal cortical-amygdalar metabolism in major depression. Ann N Y Acad Sci 1999, 877:614-637.