메뉴 건너뛰기




Volumn 14, Issue 8, 2014, Pages 869-871

Targeting cytokine networks in KRAS-driven tumorigenesis

Author keywords

cytokines; JAK; KRAS; targeted therapy; TBK1 IKKepsilon

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; RANTES; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; ANTINEOPLASTIC AGENT; KRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN;

EID: 84905001999     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/14737140.2014.928596     Document Type: Review
Times cited : (14)

References (20)
  • 1
    • 84897019899 scopus 로고    scopus 로고
    • Oncogenic K-Ras requires activation for enhanced activity
    • Huang H, Daniluk J, Liu Y, et al. Oncogenic K-Ras requires activation for enhanced activity. Oncogene 2014;33(4): 532-5
    • (2014) Oncogene , vol.33 , Issue.4 , pp. 532-535
    • Huang, H.1    Daniluk, J.2    Liu, Y.3
  • 3
    • 84896494013 scopus 로고    scopus 로고
    • IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
    • Taniguchi K, Karin M. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer. Semin Immunol 2014;26(1):54-74
    • (2014) Semin Immunol , vol.26 , Issue.1 , pp. 54-74
    • Taniguchi, K.1    Karin, M.2
  • 4
    • 40849114627 scopus 로고    scopus 로고
    • Oncogenic ras-induced expression of cytokines: A new target of anti-cancer therapeutics
    • Ancrile BB, O'Hayer KM, Counter CM. Oncogenic ras-induced expression of cytokines: A new target of anti-cancer therapeutics. Mol Interv 2008;8(1):22-7
    • (2008) Mol Interv , vol.8 , Issue.1 , pp. 22-27
    • Ancrile, B.B.1    O'Hayer, K.M.2    Counter, C.M.3
  • 5
    • 84894071177 scopus 로고    scopus 로고
    • Loss of p53 attenuates the contribution of il-6 deletion on suppressed tumor progression and extended survival in kras-driven murine lung cancer
    • Tan X, Carretero J, Chen Z, et al. Loss of p53 attenuates the contribution of il-6 deletion on suppressed tumor progression and extended survival in kras-driven murine lung cancer. PLoS One 2013;8(11):e80885
    • (2013) PLoS One , vol.8 , Issue.11
    • Tan, X.1    Carretero, J.2    Chen, Z.3
  • 6
    • 79953756112 scopus 로고    scopus 로고
    • Stat3/socs3 activation by il-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer
    • Lesina M, Kurkowski Magdalena U, Ludes K, et al. Stat3/socs3 activation by il-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer. Cancer Cell 2011;19(4):456-69
    • (2011) Cancer Cell , vol.19 , Issue.4 , pp. 456-469
    • Lesina, M.1    Kurkowski Magdalena, U.2    Ludes, K.3
  • 7
    • 79960383874 scopus 로고    scopus 로고
    • Stat3 plays a critical role in kras-induced pancreatic tumorigenesis
    • Corcoran RB, Contino G, Deshpande V, et al. STAT3 plays a critical role in kras-induced pancreatic tumorigenesis. Cancer Res 2011;71(14):5020-9
    • (2011) Cancer Res , vol.71 , Issue.14 , pp. 5020-5029
    • Corcoran, R.B.1    Contino, G.2    Deshpande, V.3
  • 8
    • 84889840938 scopus 로고    scopus 로고
    • Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase
    • Gong L, Cumpian AC, da Silva Caetano M, et al. Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase. Mol Cancer 2013;12(1):154
    • (2013) Mol Cancer , vol.12 , Issue.1 , pp. 154
    • Gong, L.1    Cumpian, A.C.2    Da Silva Caetano, M.3
  • 9
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • Karnoub AE, Dash AB, Vo AP, et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007;449(7162):557-63
    • (2007) Nature , vol.449 , Issue.7162 , pp. 557-563
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3
  • 10
    • 84897950139 scopus 로고    scopus 로고
    • Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit
    • Zhu Z, Aref AR, Cohoon TJ, et al. Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit. Cancer Discov 2014;4(4):452-65
    • (2014) Cancer Discov , vol.4 , Issue.4 , pp. 452-465
    • Zhu, Z.1    Aref, A.R.2    Cohoon, T.J.3
  • 11
    • 84855946746 scopus 로고    scopus 로고
    • Krasg12d-induced ikk2/b/nf-kb activation by il-1a and p62 feed forward loops is required for development of pancreatic ductal adenocarcinoma
    • Ling J, Kang YA, Zhao R, et al. Krasg12d-induced ikk2/b/nf-kb activation by il-1a and p62 feed forward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell 2012; 21(1):105-20
    • (2012) Cancer Cell , vol.21 , Issue.1 , pp. 105-120
    • Ling, J.1    Kang, Y.A.2    Zhao, R.3
  • 12
    • 84859710888 scopus 로고    scopus 로고
    • An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice
    • Daniluk J, Liu Y, Deng D, et al. An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. J Clin Invest 2012;122(4):1519-28
    • (2012) J Clin Invest , vol.122 , Issue.4 , pp. 1519-1528
    • Daniluk, J.1    Liu, Y.2    Deng, D.3
  • 13
    • 70449109147 scopus 로고    scopus 로고
    • Requirement for NF-kB signalling in a mouse model of lung adenocarcinoma
    • Meylan E, Dooley AL, Feldser DM, et al. Requirement for NF-kB signalling in a mouse model of lung adenocarcinoma. Nature 2009;462(7269):104-7
    • (2009) Nature , vol.462 , Issue.7269 , pp. 104-107
    • Meylan, E.1    Dooley, A.L.2    Feldser, D.M.3
  • 14
    • 83955165140 scopus 로고    scopus 로고
    • Response and resistance to nf-B. Inhibitors in mouse models of lung adenocarcinoma
    • Xue W, Meylan E, Oliver TG, et al. Response and Resistance to NF-B. Inhibitors in Mouse Models of Lung Adenocarcinoma. Cancer Discov 2011;1(3): 236-47
    • (2011) Cancer Discov , vol.1 , Issue.3 , pp. 236-247
    • Xue, W.1    Meylan, E.2    Oliver, T.G.3
  • 15
    • 70449091786 scopus 로고    scopus 로고
    • Systematic rna interference reveals that oncogenic kras-driven cancers require tbk1
    • Barbie DA, Tamayo P, Boehm JS, et al. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature 2009;462(7269):108-12
    • (2009) Nature , vol.462 , Issue.7269 , pp. 108-112
    • Barbie, D.A.1    Tamayo, P.2    Boehm, J.S.3
  • 16
    • 33749165933 scopus 로고    scopus 로고
    • Ralb gtpase-mediated activation of the ikb family kinase tbk1 couples innate immune signaling to tumor cell survival
    • Chien Y, Kim S, Bumeister R, et al. RalB GTPase-mediated activation of the ikb family kinase tbk1 couples innate immune signaling to tumor cell survival. Cell 2006; 127(1):157-70
    • (2006) Cell , vol.127 , Issue.1 , pp. 157-170
    • Chien, Y.1    Kim, S.2    Bumeister, R.3
  • 17
    • 84872201790 scopus 로고    scopus 로고
    • Ikbke is induced by stat3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer
    • Guo J, Kim D, Gao J, et al. IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer. Oncogene 2012; 32(2):151-9
    • (2012) Oncogene , vol.32 , Issue.2 , pp. 151-159
    • Guo, J.1    Kim, D.2    Gao, J.3
  • 18
    • 84876240899 scopus 로고    scopus 로고
    • The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system
    • Strickson S, Campbell David G, Emmerich Christoph H, et al. The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system. Biochem J 2013;451(3):427-37
    • (2013) Biochem J , vol.451 , Issue.3 , pp. 427-437
    • Strickson, S.1    Campbell David, G.2    Emmerich Christoph, H.3
  • 19
    • 84857828112 scopus 로고    scopus 로고
    • Challenges facing jak inhibitor therapy for myeloproliferative neoplasms
    • Tefferi A. Challenges facing JAK inhibitor therapy for myeloproliferative neoplasms. N Engl J Med 2012;366(9):844-6
    • (2012) N Engl J Med , vol.366 , Issue.9 , pp. 844-846
    • Tefferi, A.1
  • 20
    • 84878951826 scopus 로고    scopus 로고
    • Safety and efficacy of CYT387 a JAK1 and JAK2 inhibitor in myelofibrosis
    • Pardanani A, Laborde RR, Lasho TL, et al. Safety and efficacy of CYT387, a JAK1 and JAK2 inhibitor, in myelofibrosis. Leukemia 2013;27(6):1322-7
    • (2013) Leukemia , vol.27 , Issue.6 , pp. 1322-1327
    • Pardanani, A.1    Laborde, R.R.2    Lasho, T.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.