Injectable self-gelling composites for bone tissue engineering based on gellan gum hydrogel enriched with different bioglasses

Biomedical Materials (Bristol)

Volumn 9, Issue 4, 2014, Pages

  Douglas, Timothy E L ^a   Piwowarczyk, Wojciech ^b   Pamula, Elzbieta ^b   Liskova, Jana ^c   Schaubroeck, David ^d   Leeuwenburgh, Sander C G ^e   Brackman, Gilles ^a   Balcaen, Lieve ^a   Detsch, Rainer ^f   Declercq, Heidi ^a   Cholewa Kowalska, Katarzyna ^b   Dokupil, Agnieszka ^b   Cuijpers, Vincent M J I ^e   Vanhaecke, Frank ^e   Cornelissen, Ria ^a   Coenye, Tom ^a   Boccaccini, Aldo R ^f   Dubruel, Peter ^a  

^a GHENT UNIVERSITY   (Belgium)

^b AGH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Poland)

^c INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^d GHENT UNIVERSITY   (Belgium)

^e RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^f UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

bioglass; bone tissue engineering; gellan gum; hydrogel; injectable; osteoblast

Indexed keywords

BACTERIA; BIOACTIVE GLASS; BIOCOMPATIBILITY; BONE; CALCIUM; CELL CULTURE; MECHANICAL TESTING; OSTEOBLASTS; PHOSPHATE MINERALS; SOL-GELS; TISSUE ENGINEERING;

ANTI-BACTERIAL ACTIVITY; ANTIBACTERIAL PROPERTIES; BIOLOGICAL CHARACTERIZATION; BONE TISSUE ENGINEERING; GELLAN GUM; INJECTABLE; MESENCHYMAL STEM CELL; STAPHYLOCOCCUS AUREUS;

HYDROGELS;

ANTIINFECTIVE AGENT; BACTERIAL POLYSACCHARIDE; BIOGLASS; BONE CEMENT; CALCIUM PHOSPHATE; CERAMICS; GELLAN; HYDROGEL; POLYMER;

ANIMAL; BONE; CELL ADHESION; CELL PROLIFERATION; CELL SURVIVAL; CERAMICS; CHEMISTRY; COMPRESSIVE STRENGTH; DRUG EFFECTS; HYDROGEL; INFRARED SPECTROSCOPY; MATERIALS TESTING; MECHANICAL STRESS; MESENCHYMAL STROMA CELL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICRO-COMPUTED TOMOGRAPHY; PHASE TRANSITION; PROCEDURES; RAT; REGENERATION; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; X RAY DIFFRACTION;

ANIMALS; ANTI-BACTERIAL AGENTS; BONE AND BONES; BONE CEMENTS; CALCIUM PHOSPHATES; CELL ADHESION; CELL PROLIFERATION; CELL SURVIVAL; CERAMICS; COMPRESSIVE STRENGTH; HYDROGELS; MATERIALS TESTING; MESENCHYMAL STROMAL CELLS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROSCOPY, ELECTRON, SCANNING; PHASE TRANSITION; POLYMERS; POLYSACCHARIDES, BACTERIAL; RATS; REGENERATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRESS, MECHANICAL; TISSUE ENGINEERING; X-RAY DIFFRACTION; X-RAY MICROTOMOGRAPHY;

EID: 84904976163     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/9/4/045014     Document Type: Article

References (46)

1. Allan I, Newman H and Wilson M 2001 Antibacterial activity of particulate Bioglass (R) against supra- and subgingival bacteria Biomaterials 22 1683-7 (Pubitemid 32551920)
2. Bacakova L and Svorcik V 2008 Cell colonization control by physical and chemical modification of materials Cell Growth Processes: New Research ed D Kimura (Hauppauge, NY: Nova Science Publishers), pp. 1-54
3. Bellantone M, Williams H D and Hench L L 2002 Broad-spectrum bactericidal activity of Ag2O-doped bioactive glass Antimicrob. Agents Chemother. 46 1940-45 (Pubitemid 34537304)
4. Boanini E, Torricelli P, Fini M, Sima F, Serban N, Mihailescu I N and Bigi A 2012 Magnesium and strontium doped octacalcium phosphate thin films by matrix assisted pulsed laser evaporation J. Inorg. Biochem. 107 65-72
5. Bracci B, Torricelli P, Panzavolta S, Boanini E, Giardino R and Bigi A 2009 Effect of Mg(2+), Sr(2+), and Mn(2+) on the chemico-physical and in vitro biological properties of calcium phosphate biomimetic coatings J. Inorg. Biochem. 103 1666-74
6. Brackman G, Cos P, Maes L, Nelis H J and Coenye T 2011 Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo Antimicrob. Agents Chemother. 55 2655-61
7. Brunner T J, Grass R N and Stark W J 2006 Glass and bioglass nanopowders by flame synthesis Chem. Commun. (Camb) 2006 1384-6
8. Cai Y L, Zhang J J, Zhang S, Venkatraman S S, Zeng X T, Du H J and Mondal D 2010 Osteoblastic cell response on fluoridated hydroxyapatite coatings: the effect of magnesium incorporation Biomed. Mater. 5 054114
9. Douglas T et al 2012a Enzymatic mineralization of gellan gum hydrogel for bone tissue-engineering applications and its enhancement by polydopamine J. Tissue Eng. Regen. Med. doi:10.1002/term.1616
10. Douglas T E et al 2012b Enzymatic mineralization of hydrogels for bone tissue engineering by incorporation of alkaline phosphatase Macromol. Biosci. 12 1077-89
11. Douglas T E L et al 2014a Generation of composites for bone tissue engineering applications consisting of gellan gum hydrogels mineralized with calcium and magnesium phosphate phases by enzymatic means J. Tissue Eng. Regen. Med. doi:10.1002/term.1875
12. Douglas T E L, Pilarek M, Kalaszczynska I, Senderek I, Skwarczynska A, Cuijpers V M J I, Modrzejewska Z, Lewandowska-Szumiel M and Dubruel P 2014b Enrichment of chitosan hydrogels with perfluorodecalin promotes gelation and stem cell vitality Mater. Lett. 128 79-84
13. Fan J, Gong Y, Ren L, Varshney R R, Cai D. and Wang D A 2010 In vitro engineered cartilage using synovium-derived mesenchymal stem cells with injectable gellan hydrogels Acta Biomater. 6 1178-85
14. Fialho A M, Moreira L M, Granja A T, Popescu A O, Hoffmann K and Sa-Correia I 2008 Occurrence, production, and applications of gellan: current state and perspectives Appl. Microbiol. Biotechnol. 79 889-900
15. Garcia-Fernandez M J, Brackman G, Coenye T, Concheiro A and Alvarez-Lorenzo C 2013 Antiseptic cyclodextrin-functionalized hydrogels and gauzes for loading and delivery of benzalkonium chloride Biofouling 29 261-71
16. Gassling V, Douglas T E, Purcz N, Schaubroeck D, Balcaen L, Bliznuk V, Declercq H A, Vanhaecke F and Dubruel P 2013a Magnesium-enhanced enzymatically mineralized platelet-rich fibrin for bone regeneration applications Biomed. Mater. 8 055001
17. Gassling V, Hedderich J, Acil Y, Purcz N, Wiltfang J and Douglas T 2013b Comparison of platelet rich fibrin and collagen as osteoblast-seeded scaffolds for bone tissue engineering applications Clin. Oral Implants Res. 24 320-8
18. Giavasis I, Harvey L M and Mcneil B 2000 Gellan gum. Crit. Rev. Biotechnol. 20 177-211
19. Gorriti M F, Lopez J M P, Boccaccini A R, Audisio C and Gorustovich A A 2009 In vitro Study of the Antibacterial Activity of Bioactive Glass-ceramic Scaffolds Adv. Eng. Mater. 11 B67-70
20. Gorustovich A A, Roether J A and Boccaccini A R 2010 Effect of bioactive glasses on angiogenesis: a review of in vitro and in vivo evidences Tissue Eng. Part B-Rev. 16 199-207
21. Gubler M, Brunner T J, Zehnder M, Waltimo T, Sener B and Stark W J 2008 Do bioactive glasses convey a disinfecting mechanism beyond a mere increase in pH? Int. Endod. J. 41 670-8
22. Hu S, Chang J, Liu M Q and Ning C Q 2009 Study on antibacterial effect of 45S5 Bioglass(A (R)) J. Mater. Sci. Mater. Med. 20 281-6
23. Hum J and Boccaccini A R 2012 Bioactive glasses as carriers for bioactive molecules and therapeutic drugs: a review J. Mater. Sci. Mater. Med. 23 2317-33
24. Jones J R 2013 Review of bioactive glass: from Hench to hybrids Acta Biomater. 9 4457-4486
25. Killion J A, Kehoe S, Geever L M, Devine D M, Sheehan E, Boyd D and Higginbotham C L 2013 Hydrogel/bioactive glass composites for bone regeneration applications: Synthesis and characterisation Mater. Sci. Eng. C Mater. Biol. Appl. 33 4203-12
26. Kokubo T, Ito S, Huang Z T, Hayashi T, Sakka S, Kitsugi T and Yamamuro T 1990 Ca,P-rich layer formed on high-strength bioactive glass-ceramic A-W J. Biomed. Mater. Res. 24 331-43 (Pubitemid 20132804)
27. Koutsopoulos S 2002 Synthesis and characterization of hydroxyapatite crystals: a review study on the analytical methods J. Biomed. Mater. Res. 62 600-12
28. Laczka M, Cholewa-Kowalska K, Laczka-Osyczka A, Tworzydlo M and Turyna B 2000 Gel-derived materials of a CaO-P(2) O(5)-SiO(2) system modified by boron, sodium, magnesium, aluminum, and fluorine compounds J. Biomed. Mater. Res. 52 601-12
29. Lamers E, van Horssen R, te Riet J, van Delft F C M J M, Luttge R, Walboomers X F and Jansen J A 2010 The influence of nanoscale topographical cues on initial osteoblast morphology and migration Eur. Cells Mater. 20 329-43
30. Legeros R Z 1991 Calcium Phosphates in Oral Biology and Medicine (San Francisco: Karger)
31. Maeno S, Niki Y, Matsumoto H, Morioka H, Yatabe T, Funayama A, Toyama Y, Taguchi T and Tanaka J 2005 The effect of calcium ion concentration on osteoblast viability, proliferation and differentiation in monolayer and 3D culture Biomaterials 26 4847-55 (Pubitemid 40343032)
32. Marelli B, Ghezzi C E, Barralet J E, Boccaccini A R and Nazhat S N 2010 Three-dimensional mineralization of dense nanofibrillar collagen-bioglass hybrid scaffolds Biomacromolecules 11 1470-9
33. Marelli B, Ghezzi C E, Mohn D, Stark W J, Barralet J E, Boccaccini A R and Nazhat S N 2011 Accelerated mineralization of dense collagen-nano bioactive glass hybrid gels increases scaffold stiffness and regulates osteoblastic function Biomaterials 32 8915-26
34. Misra S K, Ansari T I, Valappil S P, Mohn D, Philip S E, Stark W J, Roy I, Knowles J C, Salih V and Boccaccini A R 2010 Poly (3-hydroxybutyrate) multifunctional composite scaffolds for tissue engineering applications Biomaterials 31 2806-15
35. Okamoto T and Kubota K 1996 Sol-gel transition of polysaccharide gellan gum Carbohydr. Polym. 30 149-53 (Pubitemid 126338598)
36. Oliveira J T, Martins L, Picciochi R, Malafaya P B, Sousa R A, Neves N M, Mano J F and Reis R L 2010 Gellan gum: a new biomaterial for cartilage tissue engineering applications J. Biomed. Mater. Res. A 93 852-63
37. Pamula E et al 2011 Degradation, bioactivity, and osteogenic potential of composites made of PLGA and two different sol-gel bioactive glasses Ann. Biomed. Eng. 39 2114-29
38. Pleshko N, Boskey A and Mendelsohn R 1991 Novel infrared spectroscopic method for the determination of crystallinity of hydroxyapatite minerals Biophys. J. 60 786-93
39. Rivadeneira J, Audisio M C, Boccaccini A R and Gorustovich A A 2013 In vitro antistaphylococcal effects of a novel 45S5 bioglass/agar-gelatin biocomposite films J. Appl. Microbiol. 115 604-12
40. Sader M S, Legeros R Z and Soares G A 2009 Human osteoblasts adhesion and proliferation on magnesium-substituted tricalcium phosphate dense tablets J. Mater. Sci. Mater. Med. 20 521-7
41. Stoor P, Soderling E and Salonen J I 1998 Antibacterial effects of a bioactive glass paste on oral microorganisms Acta Odontol. Scand. 56 161-5 (Pubitemid 28330891)
42. Vargas G E, Durand L A H, Cadena V, Romero M, Mesones R V and Mačković M 2013 Effect of nano-sized bioactive glass particles on the angiogenic properties of collagen based composites J. Mater. Sci.: Mater. Med. 24 1261-9
43. Xie Z P, Zhang C Q, Yi C Q, Qiu J J, Wang J Q and Zhou J 2008 Failure of particulate bioglass to prevent experimental staphylococcal infection of open tibial fractures J. Antimicrob. Chemother. 62 1162-3
44. Xu H, Wang Y J, Zheng Y D, Chen X F, Ren L, Wu G and Huang X S 2007 Preparation and characterization of bioglass/polyvinyl alcohol composite hydrogel Biomed. Mater. 2 62-6 (Pubitemid 46795264)
45. Zehnder M, Waltimo N, Sener B and Soderling E 2006 Dentin enhances the effectiveness of bioactive glass S53P4 against a strain of Enterococcus faecalis Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 101 530-5. (Pubitemid 43396705)
46. Zeng Q Y, Han Y, Li H Y and Chang J 2014 Bioglass/alginate composite hydrogel beads as cell carriers for bone regeneration J. Biomed. Mater. Res. Part B-Appl. Biomater. 102 42-51