Evaluation of a procoagulant phospholipid functional assay as a routine test for measuring circulating microparticle activity

Blood Coagulation and Fibrinolysis

Volumn 25, Issue 5, 2014, Pages 534-537

  Campello, Elena ^a   Spiezia, Luca ^a   Radu, Claudia M ^a   Gavasso, Sabrina ^a   Woodhams, Barry ^b   Simioni, Paolo ^a  

^a UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^b HaemaCon Ltd   (United Kingdom)

Author keywords

Flow cytometry; Microparticles; Procoagulant assays

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5 LEIDEN; LIPOCORTIN 5; PHOSPHOLIPID; PROCOAGULANT; PROCOAGULANT PHOSPHOLIPID; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ASSAY; BIOLOGICAL ACTIVITY; BLOOD CLOTTING TIME; BLOOD SAMPLING; BODY MASS; CANCER PATIENT; COMPARATIVE STUDY; CROSS-SECTIONAL STUDY; FEMALE; FLOW CYTOMETRY; HETEROZYGOTE; HOMOZYGOTE; HUMAN; LIMIT OF DETECTION; MAJOR CLINICAL STUDY; MALE; MEMBRANE MICROPARTICLE; NEOPLASM; OBESITY; PRIORITY JOURNAL; THROMBOCYTE FREE PLASMA; VENOUS THROMBOEMBOLISM; BLOOD CLOTTING TEST; METABOLISM; MIDDLE AGED; PROCEDURES; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BLOOD COAGULATION TESTS; CELL-DERIVED MICROPARTICLES; FEMALE; HUMANS; MALE; MIDDLE AGED; PHOSPHOLIPIDS;

EID: 84904967516     PISSN: 09575235     EISSN: 14735733     Source Type: Journal    
DOI: 10.1097/MBC.0000000000000068     Document Type: Article

References (17)

1. Owens AP III, Mackman N. Microparticles in hemostasis and thrombosis. Circ Res 2011; 108: 1284-1297.
2. Barteneva NS, Fasler-Kan E, Bernimoulin M, Stern JN, Ponomarev ED, Duckett L, et al. Circulating microparticles: square the circle. BMC Cell Biology 2013; 14: 23.
3. Yuana Y, Bertina RM, Osanto S. Preanalytical and analytical issues in the analysis of blood microparticles. Thromb Haemost 2011; 105: 396-408.
4. Lacroix R, Robert S, Poncelet P, Kasthuri RS, Key NS, Dignat-George F, ISTH SSC Workshop. Standardization of platelet-derived microparticle enumeration by flow cytometry with calibrated beads: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop. J Thromb Haemost 2010; 8: 2571-2574.
5. Connor DE, Exner T, Ma DD, Joseph JE. Detection of the procoagulant activity of microparticle-associated phosphatidylserine using XACT. Blood Coagul Fibrinolysis 2009; 20: 558-564.
6. Yuana Y, Oosterkamp TH, Bahatyrova S, Ashcroft B, Garcia Rodriguez P, Bertina RM, et al. Atomic force microscopy: a novel approach to the detection of nanosized blood microparticles. J Thromb Haemost 2010; 8: 315-323.
7. Thielbeer F, Donaldson K, Bradley M. Zeta potential mediated reaction monitoring on nano and microparticles. Bioconjug Chem 2011; 22: 144-150.
8. Momen-Heravi F, Balaj L, Alian S, Tigges J, Toxavidis V, Ericsson M, et al. Alternative methods for characterization of extracellular vesicles. Front Physiol 2012; 3: 354-362.
9. Key NS, Chantrathammachart P, Moody PW, Chang JY. Membrane microparticles in VTEand cancer. ThrombRes 2010; 125 (Suppl 2): 80-83.
10. Campello E, Spiezia L, Radu CM, Bulato C, Castelli M, Gavasso S, et al. Endothelial, platelet and tissue factor-bearing microparticles in cancer patients with and without venous thrombembolism. Thromb Res 2011; 127: 473-477.
11. Campello E, Spiezia L, Radu CM, Bon M, Gavasso S, Zerbinati P, et al. Circulating microparticles in carriers of factor V Leiden with and without a history of venous thrombosis. Thromb Haemost 2012; 108: 633-639.
12. Berckmans R, van Beers E, van den Goor J, van Doormaal F, Tushuizen J, Diamant M, et al. Measuring the real contribution of microparticle-exposed procoagulant phospholipids to coagulation: a new assay. J Thromb Haemost 2009; 7 (Suppl 2): 583; Abstract: PP-MO-769.
13. van Dreden P, Rousseau A, Fontaine S, Woodhams BJ, Exner T. Monitoring patient plasma platelet-derived procoagulant microparticles (PMP) with a new factor Xa-based clotting test (XaCT). Blood Coagul Fibrinolysis 2009; 20: 494-502.
14. Noubouossie DC, Lê PQ, Rozen L, Debaugnies F, Ferster A, Demulder A. Evaluation of the procoagulant activity of endogenous phospholipids in the platelet-free plasma of children with sickle cell disease using functional assays. Thromb Res 2012; 130: 259-264.
15. Stagnara J, Garnache Ottou F, Angelot F, Mourey G, Seilles E, Biichlé S, et al. Correlation between platelet-derived microparticle enumeration by flow cytometry and phospholipid-dependent procoagulant activity in microparticles: the centrifugation step matters!. Thromb Haemost 2012; 107: 1185-1187.
16. Lacroix R, Judicone C, Mooberry M, Boucekine M, Key NS, Dignat-George F, The ISTH SSC Workshop. Standardization of preanalytical variables in plasma microparticle determination: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop. J Thromb Haemost 2013; 11: 1190-1193.
17. Connor DE, Exner T, Ma DD, Joseph JE. The majority of circulating plateletderived microparticles fail to bind annexin V, lack phospholipid- dependent procoagulant activity and demonstrate greater expression of glycoprotein Ib. Thromb Haemost 2010; 103: 1044-1052.