Matrix segregation as the major cause for sample inhomogeneity in MALDI dried droplet spots

Journal of the American Society for Mass Spectrometry

Volumn 25, Issue 8, 2014, Pages 1356-1363

  Gabriel, Stefan J ^a   Schwarzinger, Clemens ^b   Schwarzinger, Bettina ^b   Panne, Ulrich ^a,c   Weidner, Steffen M ^a  

^a BAM FEDERAL INSTITUTE FOR MATERIALS RESEARCH AND TESTING   (Germany)

^b JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Dried droplet; Imaging MS; MALDI; Matrix segregation; Polymers; Sample preparation

Indexed keywords

DROPS; INFRARED IMAGING; SECONDARY ION MASS SPECTROMETRY;

DRYING DROPLETS; HOMOGENEOUS SAMPLES; IMAGING MASS SPECTROMETRY; IMAGING SPECTROSCOPY; MALDI; MATRIX SOLUTION; SAMPLE PREPARATION; SYNTHETIC POLYMERS;

POLYMERS;

POLYMER; SOLVENT; 2,5-DIHYDROXYBENZOIC ACID; 2-((2E)-3-(4-TERT-BUTYLPHENYL)-2-METHYLPROP-2-ENYLIDENE)MALONONITRILE; ACETONITRILE; ACETONITRILE DERIVATIVE; ARTIFICIAL MEMBRANE; FURAN DERIVATIVE; GENTISIC ACID; MACROGOL DERIVATIVE; NITRILE; POLY(METHYL METHACRYLATE); POLYSTYRENE DERIVATIVE; RETINOIC ACID; TETRAHYDROFURAN;

ARTICLE; CAPILLARY FLOW; CHEMICAL PHENOMENA; CRYSTALLIZATION; DRIED DROPLET SPOT MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; ELECTROSPRAY; INFRARED SPECTROSCOPY; MASS SPECTROMETER; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MATRIX SEGREGATION; MICROSCOPY; MOLECULAR WEIGHT; ARTIFICIAL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ELECTROCHEMICAL ANALYSIS; FLUORESCENCE IMAGING; INFRARED SPECTROPHOTOMETRY; MASS SPECTROMETRY; REPRODUCIBILITY; VOLATILIZATION;

ACETONITRILES; ELECTROCHEMICAL TECHNIQUES; FURANS; GENTISATES; MEMBRANES, ARTIFICIAL; MICROSCOPY; MODELS, MOLECULAR; MOLECULAR WEIGHT; NITRILES; OPTICAL IMAGING; POLYETHYLENE GLYCOLS; POLYMETHYL METHACRYLATE; POLYSTYRENES; REPRODUCIBILITY OF RESULTS; SOLVENTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPECTROPHOTOMETRY, INFRARED; TRETINOIN; VOLATILIZATION;

EID: 84904901049     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-014-0913-0     Document Type: Article

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