Vitamin D insufficiency and subclinical atherosclerosis in non-diabetic males living with HIV

Journal of the International AIDS Society

Volumn 17, Issue , 2014, Pages

  Portilla, Joaquín ^a,b   Moreno Pérez, Óscar ^b   Serna Candel, Carmen ^c   Escoín, Corina ^a   Alfayate, Rocio ^d   Reus, Sergio ^a,b   Merino, Esperanza ^a,b   Boix, Vicente ^a,b   Giner, Livia ^a   Sánchez Payá, José ^e   Picó, Antonio ^b  

^a Alicante University General Hospital FISABIO   (Spain)

^b MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^c HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^d Alicante University General Hospital FISABIO   (Spain)

^e Alicante University General Hospital FISABIO   (Spain)

Author keywords

Adipokines; Antiretroviral treatment; Atherosclerosis; Carotid intima media thickness; HIV; Vitamin D insufficiency

Indexed keywords

25 HYDROXYVITAMIN D; ABACAVIR; ADIPOCYTOKINE; ATAZANAVIR; C REACTIVE PROTEIN; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; FOSAMPRENAVIR; GLUCOSE; INTERLEUKIN 6; LAMIVUDINE; LIPID; LOPINAVIR; NEVIRAPINE; PLASMINOGEN ACTIVATOR INHIBITOR 1; STAVUDINE; TENOFOVIR; TIPRANAVIR; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ZIDOVUDINE;

ADULT; AMBULATORY CARE; ANTIVIRAL THERAPY; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; COMMON CAROTID ARTERY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIPODYSTROPHY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PREVALENCE; PRIORITY JOURNAL; SEDENTARY LIFESTYLE; TRIACYLGLYCEROL BLOOD LEVEL; VITAMIN D DEFICIENCY;

ADIPOKINES; ANTIRETROVIRAL TREATMENT; ATHEROSCLEROSIS; CAROTID INTIMA MEDIA THICKNESS; HIV; VITAMIN D INSUFFICIENCY;

ADULT; ASYMPTOMATIC DISEASES; ATHEROSCLEROSIS; BLOOD GLUCOSE; C-REACTIVE PROTEIN; CAROTID INTIMA-MEDIA THICKNESS; CROSS-SECTIONAL STUDIES; HIV INFECTIONS; HUMANS; INTERLEUKIN-6; LIPIDS; LOGISTIC MODELS; MALE; PLASMINOGEN ACTIVATOR INHIBITOR 1; RISK FACTORS; TUMOR NECROSIS FACTOR-ALPHA; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84904878493     PISSN: None     EISSN: 17582652     Source Type: Journal    
DOI: 10.7448/IAS.17.1.18945     Document Type: Article

References (38)

1. Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006;81(3):353-73. (Pubitemid 43334631)
2. Viard JP, Souberbielle JC, Kirk O, Reekie J, Knysz B, Losso M, et al. EuroSIDA Study Group. Vitamin D and clinical disease progression in HIV infection: results from the EuroSIDA study. AIDS. 2011;25:1305-15.
3. Dao CN, Patel P, Overton ET, Rhame F, Pals SL, Johnson C, et al. Study to understand the natural history of HIV and AIDS in the era of effective therapy (SUN) investigators. Low vitamin D among HIV-infected adults: prevalence of and risk factors for low vitamin D levels in a cohort of HIV-infected adults and comparison to prevalence among adults in the US general population. Clin Infect Dis. 2011;52:396-405.
4. Rosen CJ. Clinical practice. Vitamin D insufficiency. N Engl J Med. 2011; 364:248-54.
5. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Endocrine Society. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96:1911-30.
6. Wu-Wong JR, Nakane M, Ma J, Ruan X, Kroeger PE. Effects of vitamin D analogs on gene expression profiling in human coronary artery smooth muscle cells. Atherosclerosis. 2006;186:20-8.
7. Zehnder D, Bland R, Chana RS, Wheeler DC, Howie AJ, Williams MC, et al. Synthesis of 1,25-dihydroxyvitamin D(3) by human endothelial cells is regulated by inflammatory cytokines: a novel autocrine determinant of vascular cell adhesion. J Am Soc Nephrol. 2002;13:621-9. (Pubitemid 34183926)
8. Li YC, Kong J, Wei M, Chen ZF, Liu SQ, Cao LP. 1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the rennin angiotensin system. J Clin Invest. 2002;110:229-38. (Pubitemid 34787360)
9. Oh J, Weng S, Felton SK, Bhandare S, Riek A, Butler B, et al. 1,25(OH)2 vitamin D inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus. Circulation. 2009;120:687-98.
10. Giallauria F, Milaneschi Y, Tanaka T, Maggio M, Canepa M, Elango P, et al. Arterial stiffness and vitamin D levels: the Baltimore longitudinal study of aging. J Clin Endocrinol Metab. 2012;97:3717-23.
11. Autier P, Boniol M, Pizot C, Mullie P. Vitamin D status and ill health: a systematic review. Lancet Diabetes Endocrinol 2014;2:76-89.
12. Ross AC, Judd S, Kumari M, Hileman C, Storer N, Labbato D, et al. Vitamin D is linked to carotid intima-media thickness and immune reconstitution in HIV-positive individuals. Antivir Ther. 2011;16:555-63.
13. Choi AI, Lo JC, Mulligan K, Schnell A, Kalapus SC, Li Y, et al. Association of vitamin D insufficiency with carotid intima-media thickness in HIV-infected persons. Clin Infect Dis. 2011;52:941-4.
14. Touboul PJ, Hennerici MG, Meairs S, Adams H, Amarenco P, Bornstein N, et al. Mannheim carotid intima-media thickness and plaque consensus (2004-2006-2011). An update on behalf of the advisory board of the 3rd, 4th and 5th watching the risk symposia, at the 13th, 15th and 20th European Stroke Conferences, Mannheim, Germany, 2004, Brussels, Belgium, 2006, and Hamburg, Germany, 2011. Cerebrovasc Dis. 2004;34:290-6.
15. Carr A, Emery S, Law M, Puls R, Lundgren JD, Powderly WG. HIV lipodystrophy case definition study group. An objective case definition of lipodystrophy in HIV-infected adults: a case-control study. Lancet. 2003;361:726-35. (Pubitemid 36293626)
16. Mueller NJ, Fux CA, Ledergerber B, Elzi L, Schmid P, Dang T, et al. Swiss HIV Cohort Study. High prevalence of severe vitamin D deficiency in combined antiretroviral therapy-naive and successfully treated Swiss HIV patients. AIDS. 2010;24:1127-34.
17. Adeyemi OM, Agniel D, French AL, Tien PC, Weber K, Glesby MJ, et al. Vitamin D deficiency in HIV-infected and HIV-uninfected women in the United States. J Acquir Immune Defic Syndr. 2011;57:197-203.
18. Vescini F, Cozzi-Lepri A, Borderi M, Re MC, Maggiolo F, De Luca A, et al. Icona Foundation Study Group. Prevalence of hypovitaminosis D and factors associated with vitamin D deficiency and morbidity among HIV-infected patients enrolled in a large Italian cohort. J Acquir Immune Defic Syndr. 2011;58:163-72.
19. Van Den Bout-Van Den Beukel CJ, Fievez L, Michels M, Sweep FC, Hermus AR, Bosch ME, et al. Vitamin D deficiency among HIV type 1-infected individuals in the Netherlands: effects of antiretroviral therapy. AIDS Res Hum Retroviruses. 2008;24:1375-82.
20. Brown TT, McComsey GA. Association between initiation of antiretroviral therapy with efavirenz and decreases in 25-hydroxyvitamin D. Antivir Ther. 2010;15:425-9.
21. Welz T, Childs K, Ibrahim F, Poulton M, Taylor CB, Moniz CF, et al. Efavirenz is associated with severe vitamin D deficiency and increased alkaline phosphatase. AIDS. 2010;24:1923-8.
22. Fox J, Peters B, Prakash M, Arribas J, Hill A, Moecklinghoff C. Improvement in vitamin D deficiency following antiretroviral regime change: results from the MONET trial. AIDS Res Human Retroviruses. 2011;27:29-34.
23. Yin M, Stein M. The effect of antiretrovirals on vitamin D. Clin Infect Dis. 2011;52:406-8.
24. Carrelli AL, Walker MD, Lowe H, McMahon DJ, Rundek T, Sacco RL, et al. Vitamin D deficiency is associated with subclinical carotid atherosclerosis: the Northern Manhattan study. Stroke. 2011;42:2240-5.
25. Gepner AD, Ramamurthy R, Krueger DC, Korcarz CE, Binkley N, Stein JH. A prospective randomized controlled trial of the effects of vitamin D supplementation on cardiovascular disease risk. PLoS One. 2012;7:e36617.
26. Longenecker CT, Hileman CO, Carman TL, Ross AC, Seydafkan S, Brown TT, et al. Vitamin D supplementation and endothelial function in vitamin D deficient HIV-infected patients: a randomized placebo-controlled trial. Antivir Ther. 2012;17:613-21.
27. Mangili A, Polak JF, Skinner SC, Gerrior J, Sheehan H, Harrington A, et al. HIV infection and progression of carotid and coronary atherosclerosis: the CARE study. J Acquir Immune Defic Syndr. 2011;58:148-53.
28. Currier JS. Update on cardiovascular complications in HIV infection. Top HIV Med. 2009;17:98-103.
29. Sabin CA, Worm SW, Weber R, Reiss P, El-Sadr W, Dabis F, et al. Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration. Lancet. 2008;371:1417-26.
30. Friis-Møller N, Reiss P, Sabin CA, Weber R, Monforte A, El-Sadr W, et al. Class of antiretroviral drugs and the risk of myocardial infarction. N Engl J Med. 2007;356:1723-35. (Pubitemid 46658704)
31. Currier JS, Kendall MA, Henry WK, Alston-Smith B, Torriani FJ, Tebas P, et al. Progression of carotid artery intima-media thickening in HIV-infected and uninfected adults. AIDS. 2007;21:1137-45. (Pubitemid 46763284)
32. Lundgren JD, Neuhaus J, Babiker A, Cooper D, Duprez D, El-Sadr W, et al. Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients. Strategies for Management of Anti-Retroviral Therapy/INSIGHT; DAD Study Groups. AIDS. 2008;22:F17-24.
33. Van den Oord SC, Sijbrands EJ, Ten Kate GL, van Klaveren D, van Domburg RT, van der Steen AF, et al. Carotid intima-media thickness for cardiovascular risk assessment: systematic review and meta-analysis. Atherosclerosis. 2013;228:1-11.
34. Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation. 2007;115:459-67. (Pubitemid 46184197)
35. Maggi P, Lillo A, Perilli F, Maserati R, Chirianni A. Colour-Doppler ultrasonography of carotid vessels in patients treated with antiretroviral therapy: a comparative study. AIDS. 2004;18:1023-8. (Pubitemid 38591193)
36. Sankatsing RR, Wit FW, Vogel M, de Groot E, Brinkman K, Rockstroh JK, et al. Increased carotid intima-media thickness in HIV patients treated with protease inhibitors as compared to non-nucleoside reverse transcriptase inhibitors. Atherosclerosis. 2009;202(2):589-95.
37. Viscogliosi G, Andreozzi P, Marigliano V. Associations of plasma glucose levels and traits of metabolic syndrome with carotid intima media thickness in nondiabetic elderly subjects: are they mediated by insulin resistance? Metab Syndr Relat Disord. 2013;11:41-5.
38. Zhang YF, Hong J, Zhan WW, Li XY, Gu WQ, Yang YS, et al. Hyperglycaemia after glucose loading is a major predictor of preclinical atherosclerosis in nondiabetic subjects. Clin Endocrinol. 2006;64:153-7.