Inhibition of DNA replication of human papillomavirus by using zinc finger-single-chain FokI dimer hybrid

Molecular Biotechnology

Volumn 56, Issue 8, 2014, Pages 731-737

  Mino, Takashi ^a   Mori, Tomoaki ^a,b   Aoyama, Yasuhiro ^a   Sera, Takashi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

Antiviral therapy; Artificial zinc finger protein; DNA cleavage; Human DNA virus; Human papillomavirus; Hybrid nuclease; Single chain FokI dimer

Indexed keywords

ASSAYS; CHAINS; DNA; MOLECULAR BIOLOGY; PROTEINS; VIRUSES; ZINC;

ANTIVIRAL THERAPY; DNA CLEAVAGE; DNA VIRUS; HUMAN PAPILLOMAVIRUS; HYBRID NUCLEASE;

POLYMERASE CHAIN REACTION;

DIMER; HYBRID PROTEIN; REAGENT; VIRUS DNA; ZINC FINGER NUCLEASE; ENDODEOXYRIBONUCLEASE FOKI; MICROCOCCAL NUCLEASE; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE; ZINC FINGER PROTEIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA CLEAVAGE; DNA REPLICATION; DRUG CYTOTOXICITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 18; MAMMAL CELL; MTT ASSAY; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; VIRUS NEUTRALIZATION; BIOTECHNOLOGY; ENZYME SPECIFICITY; FEMALE; GENETICS; HEK293 CELL LINE; METABOLISM; PATHOGENICITY;

DNA VIRUSES; HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 18; MAMMALIA;

BINDING SITES; BIOTECHNOLOGY; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA REPLICATION; DNA, VIRAL; FEMALE; HEK293 CELLS; HUMAN PAPILLOMAVIRUS 18; HUMANS; MICROCOCCAL NUCLEASE; POLYMERASE CHAIN REACTION; SUBSTRATE SPECIFICITY; TRANSFECTION; ZINC FINGERS;

EID: 84904855034     PISSN: 10736085     EISSN: 15590305     Source Type: Journal    
DOI: 10.1007/s12033-014-9751-3     Document Type: Article

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