Molecular dynamics of the neuronal EF-hand Ca2+-sensor Caldendrin

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Reddy, Pasham Parameshwar ^a   Raghuram, Vijeta ^a,b   Hradsky, Johannes ^a   Spilker, Christina ^a   Chakraborty, Asima ^b   Sharma, Yogendra ^b   Mikhaylova, Marina ^a,c   Kreutz, Michael R ^a  

^a LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

^b CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM BINDING PROTEIN; CALCIUM ION; CALDENDRIN PROTEIN; ISOPROTEIN; MAGNESIUM ION; UNCLASSIFIED DRUG; CA2+-BINDING PROTEIN-1; CALCIUM; MAGNESIUM; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GEL FILTRATION; HYDROPHOBICITY; LIGHT SCATTERING; MOLECULAR DYNAMICS; PROTEIN BINDING; PROTEIN DOMAIN; SURFACE PLASMON RESONANCE; SURFACE PROPERTY; ANIMAL; CELL CULTURE; CHEMISTRY; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOUSE; NERVE CELL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; EF HAND MOTIFS; HEK293 CELLS; HUMANS; MAGNESIUM; MICE; MOLECULAR DYNAMICS SIMULATION; NEURONS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84904816895     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0103186     Document Type: Article

References (32)

1. 2+ signalling. Nat Rev Neurosci 8: 182-193.
2. 2+ signalling. J Neurochem 118: 695-713.
3. 2+ signaling via caldendrin and calneurons. Biochim Biophys Acta 1763: 1229-1237.
4. 2+ -binding proteins. BMC Res Notes 3: 118.
5. Seidenbecher CI, Langnaese K, Sanmarti-Vila L, Boeckers TM, Smalla KH et al. (1998) Caldendrin, a novel neuronal calcium-binding protein confined to the somato-dendritic compartment. J Biol Chem 273: 21324-21331. (Pubitemid 28385426)
6. (2+)-binding protein (CABP) subfamily with similarity to calmodulin. J Biol Chem 275: 1247-1260.
7. 2+-binding protein caldendrin: gene structure, splice isoforms, and expression in the rat central nervous system. Mol Cell Neurosci 19: 459-475.
8. Landwehr M, Redecker P, Dieterich DC, Richter K, Boeckers TM et al. (2003) Association of Caldendrin splice isoforms with secretory vesicles in neurohypophyseal axons and the pituitary. FEBS Lett 547: 189-192. (Pubitemid 36829403)
9. Haynes LP, Tepikin AV, Burgoyne RD (2004) Calcium-binding protein1 is an inhibitor of agonist-evoked, inositol 1,4,5-trisphosphate-mediated calcium signaling. J Biol Chem 279: 547-555. (Pubitemid 38044857)
10. 2+ channels. J Neurosci 24: 4698-4708.
11. 2+ channels. J Biol Chem 282: 8464-8473.
12. Seidenbecher CI, Landwehr M, Smalla KH, Kreutz M, Dieterich DC et al. (2004) Caldendrin but not calmodulin binds to light chain 3 of MAP1A/B: An association with the microtubule cytoskeleton highlighting exclusive binding partners for neuronal Ca2+-sensor proteins. J Mol Biol 336: 957-970. (Pubitemid 38201542)
13. Smalla KH, Seidenbecher CI, Tischmeyer W, Schicknick H, Wyneken U et al. (2003) Kainate-induced epileptic seizures induce a recruitment of caldendrin to the postsynaptic density in rat brain. Mol Brain Res 116: 159-162. (Pubitemid 36993707)
14. Smalla KH, Sahin J, Putzke J, Tischmeyer W, Gundelfinger ED et al. (2009) Altered postsynaptic-density-levels of Caldendrin in the para-chloroampheta- mine-induced serotonin syndrome but not in the rat ketamine model of psychosis. Neurochem Res 34: 1405-1409.
15. Bernstein HG, Sahin J, Smalla KH, Gundelfinger ED, Bogerts B et al. (2007) A reduced number of cortical neurons show increased Caldendrin protein levels in chronic schizophrenia. Schizophrenia Research 96: 246-256. (Pubitemid 47494629)
16. 2+-dependent regulation of inositol 1,4,5 trisphosphate receptors by CaBP1. J Biol Chem 284: 2472-2481.
17. Findeisen F, Minor DL Jr (2010) Structural basis for the differential effects of CaBP1 and calmodulin on Ca(V)1.2 calcium-dependent inactivation. Structure 18: 1617-1631.
18. (2+) -bound closed state: implications for target recognition. Protein Sci 20: 1356-1366.
19. 2+ binding to CaBP1, a neuron-specific regulator of calcium channels. J Biol Chem 280: 37461-37470.
20. Dieterich DC, Karpova A, Mikhaylova M, Zdobnova I, König I et al. (2008) Caldendrin-Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus. PLoS Biol. 6e34.
21. Karpova A, Mikhaylova M, Bera S, Bär J, Reddy PP et al. (2013) Encoding and transducing the synaptic or extrasynaptic origin of NMDA receptor signals to the nucleus. Cell 152: 1119-1133.
22. Mikhaylova M, Reddy PP, Munsch T, Landgraf P, Suman SK et al. (2009) Calneurons provide a calcium threshold for trans-Golgi network to plasma membrane trafficking. Proc Natl Acad Sci USA 106: 9093-9098.
23. Aravind P, Chandra K, Reddy PP, Jeromin A, Chary KV, et al. (2008) Regulatory and structural EF-hand motifs of neuronal calcium sensor-1: Mg 2+ modulates Ca2+ binding, Ca2+-induced conformational changes, and equilibrium unfolding transitions. J Mol Biol. 2008 376(4): 1100-1115.
24. Lansbergen G, Komarova Y, Modesti M, Wyman C, Hoogenraad CC et al. (2004) Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. J. Cell Biol 166: 1003-1014. (Pubitemid 39304764)
25. 2+-myristoyl switch of recoverin. J Neurochem 113: 1150-1162.
26. 2+-binding protein 1. Nat Neurosci 5: 210-217.
27. 2+ channels by calmodulin and Ca2+-binding protein-1. J Biol Chem 280: 29612-29619.
28. 2+-binding proteins. EMBO J 23: 312-321.
29. 2+ sensor proteins. Proc Natl Acad Sci USA 109: 17069-17074.
30. 2+ sensor protein, inhibits inositol trisphosphate receptors by clamping intersubunit interactions. Proc Natl Acad Sci USA 110: 8507-8512.
31. (2+). Front Mol Neurosci 5: 61.
32. Kim KY, Scholl ES, Liu X, Shepherd A, Haeseleer F, et al. (2014) Localization and expression of CaBP1/caldendrin in the mouse brain. Neuroscience. 268C: 33-47.