E2F1: A potential therapeutic target for systematic lupus erythematosus

Rheumatology International

Volumn 34, Issue 8, 2014, Pages 1175-1176

  Fang, Xin Yu ^a   Ye, Dong Qing ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AUTOANTIBODY; MICRORNA; TRANSCRIPTION FACTOR E2F1; MESSENGER RNA;

ANTIBODY PRODUCTION; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CELL CYCLE PROGRESSION; CELL MATURATION; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG TARGETING; EXPERIMENTAL THERAPY; GENE EXPRESSION; HUMAN; IMMUNE SYSTEM; IMMUNOPATHOGENESIS; IMMUNOSUPPRESSIVE TREATMENT; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; TRANSCRIPTION INITIATION; BLOOD; FEMALE; GENETICS; MALE;

E2F1 TRANSCRIPTION FACTOR; FEMALE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MICRORNAS; RNA, MESSENGER;

EID: 84904808511     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-013-2873-2     Document Type: Article

References (11)

1. Aboelenein HR, Salah S, Lashine YA, Abdelaziz AI (2013) Dual downregulation of microRNA 17-5p and E2F1 transcriptional factor in pediatric systemic lupus erythematosus patients. Rheumatol Int 33(5):1333-1338. doi:10.1007/s00296-012-2543-9
2. Bukur J, Herrmann F, Handke D, Recktenwald C, Seliger B (2010) Identification of E2F1 as an important transcription factor for the regulation of tapasin expression. J Biol Chem 285(40):30419-30426. doi:10.1074/jbc.M109. 094284
3. Zhou D, Masri S, Ye JJ, Chen S (2005) Transcriptional regulation of the mouse PNRC2 promoter by the nuclear factor Y (NFY) and E2F1. Gene 361:89-100. doi:10.1016/j.gene.2005.07.012 (Pubitemid 41506936)
4. Fang F, Wang Y, Li R, Zhao Y, Guo Y, Jiang M, Sun J, Ma Y, Ren Z, Tian Z, Wei F, Yang D, Xiao W (2010) Transcription factor E2F1 suppresses dendritic cell maturation. J Immunol 184(11):6084-6091. doi:10.4049/jimmunol.0902561
5. DeGregori J (2002) The genetics of the E2F family of transcription factors: shared functions and unique roles. Biochim Biophys Acta 1602(2):131-150
6. Cao Q, Xia Y, Azadniv M, Crispe IN (2004) The E2F-1 transcription factor promotes caspase-8 and bid expression, and enhances Fas signaling in T cells. J Immunol 173(2):1111-1117 (Pubitemid 38924286)
7. Zhu JW, Field SJ, Gore L, Thompson M, Yang H, Fujiwara Y, Cardiff RD, Greenberg M, Orkin SH, DeGregori J (2001) E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis. Mol Cell Biol 21(24):8547-8564. doi:10.1128/MCB.21.24.8547-8564.2001 (Pubitemid 33108613)
8. Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J (2001) Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 294(5546):1540-1543. doi:10.1126/science.1064890 (Pubitemid 33063928)
9. Jin O, Kavikondala S, Mok MY, Sun L, Gu J, Fu R, Chan A, Yeung J, Nie Y, Lau CS (2010) Abnormalities in circulating plasmacytoid dendritic cells in patients with systemic lupus erythematosus. Arthritis Res Ther 12(4):R137. doi:10.1186/ar3075
10. Garcia I, Murga M, Vicario A, Field SJ, Zubiaga AM (2000) A role for E2F1 in the induction of apoptosis during thymic negative selection. Cell Growth Differ 11(2):91-98 (Pubitemid 30131489)
11. Iglesias AH, Camelo S, Hwang D, Villanueva R, Stephanopoulos G, Dangond F (2004) Microarray detection of E2F pathway activation and other targets in multiple sclerosis peripheral blood mononuclear cells. J Neuroimmunol 150(1-2):163-177. doi:10.1016/j.jneuroim.2004.01.017 (Pubitemid 38481661)