Acceleration of bone formation during fracture healing by injectable collagen powder and human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase

Journal of Biomedical Materials Research - Part A

Volumn 102, Issue 9, 2014, Pages 3049-3055

  Saito, Wataru ^a   Uchida, Kentaro ^a   Ueno, Masaki ^a   Matsushita, Osamu ^b   Inoue, Gen ^a   Nishi, Nozomu ^c   Ogura, Takayuki ^d   Hattori, Shunji ^d   Fujimaki, Hisako ^a   Tanaka, Keisuke ^d   Takaso, Masashi ^a  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c KAGAWA UNIVERSITY   (Japan)

^d NIPPI RESEARCH INSTITUTE OF BIOMATRIX   (Japan)

Author keywords

Basic fibroblast growth factor; collagen binding domain; collagenase; fracture healing; injectable collagen power

Indexed keywords

BIOLOGICAL MATERIALS; BONE; CELL CULTURE; CLOSTRIDIUM; FRACTURE; IMPLANTS (SURGICAL);

BASIC FIBROBLAST GROWTH FACTOR; COLLAGEN BINDING DOMAIN; COLLAGENASE; FRACTURE HEALING; INJECTABLE COLLAGEN POWER;

COLLAGEN;

CLOSTRIDIOPEPTIDASE A; COLLAGEN; COLLAGEN BINDING BASIC FIBROBLAST GROWTH FACTOR FUSION PROTEIN; COLLAGEN BINDING PROTEIN; COLLAGENASE; FIBROBLAST GROWTH FACTOR 2; HYBRID PROTEIN; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BONE MASS; BONE MINERAL; BONE REMODELING; CALLUS; CELL PROLIFERATION; CIRCULAR DICHROISM; CONFORMATION; FEMUR FRACTURE; FRACTURE HEALING; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MICRO-COMPUTED TOMOGRAPHY; MORPHOLOGY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOTOMY; PERIOSTEUM; POWDER; ANATOMY AND HISTOLOGY; ANIMAL; CHEMISTRY; CLOSTRIDIUM; DRUG EFFECTS; ENZYMOLOGY; INJECTION; METABOLISM; PROTEIN TERTIARY STRUCTURE; RAT;

ANIMALS; BONY CALLUS; CLOSTRIDIUM; COLLAGEN; FIBROBLAST GROWTH FACTOR 2; FRACTURE HEALING; HUMANS; INJECTIONS; MALE; MICE; MICROBIAL COLLAGENASE; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS;

EID: 84904793544     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34974     Document Type: Article

References (32)

1. Nakajima F, Nakajima A, Ogasawara A, Moriya H, Yamazaki M,. Effects of a single percutaneous injection of basic fibroblast growth factor on the healing of a closed femoral shaft fracture in the rat. Calcif Tissue Int 2007; 81: 132-138.
2. Friedlaender GE, Perry CR, Cole JD, Cook SD, Cierny G, Muschler GF, Zych GA, Calhoun JH, LaForte AJ, Yin S,. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. J Bone Joint Surg Am 2001; 83-A(Suppl 1): S151-S158.
3. Govender S, Csimma C, Genant HK, Valentin-Opran A, Amit Y, Arbel R, Aro H, Atar D, Bishay M, Borner MG, Chiron P, Choong P, Cinats J, Courtenay B, Feibel R, Geulette B, Gravel C, Haas N, Raschke M, Hammacher E, van d, V, Hardy P, Holt M, Josten C, Ketterl RL, Lindeque B, Lob G, Mathevon H, McCoy G, Marsh D, Miller R, Munting E, Oevre S, Nordsletten L, Patel A, Pohl A, Rennie W, Reynders P, Rommens PM, Rondia J, Rossouw WC, Daneel PJ, Ruff S, Ruter A, Santavirta S, Schildhauer TA, Gekle C, Schnettler R, Segal D, Seiler H, Snowdowne RB, Stapert J, Taglang G, Verdonk R, Vogels L, Weckbach A, Wentzensen A, Wisniewski T,. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg Am 2002; 84-A: 2123-2134.
4. Kigami R, Sato S, Tsuchiya N, Yoshimakai T, Arai Y, Ito K,. Fgf-2 angiogenesis in bone regeneration within critical-sized bone defects in rat calvaria. Implant Dent 2013; 22: 422-427.
5. Lai RF, Zhou ZY, Chen T,. Accelerating bone generation and bone mineralization in the interparietal sutures of rats using an rhBMP-2/ACS composite after rapid expansion. Exp Anim 2013; 62: 189-196.
6. Valentin-Opran A, Wozney J, Csimma C, Lilly L, Riedel GE,. Clinical evaluation of recombinant human bone morphogenetic protein-2. Clin Orthop Relat Res 2002; 110-120.
7. Seeherman H, Li R, Wozney J,. A review of preclinical program development for evaluating injectable carriers for osteogenic factors. J Bone Joint Surg Am 2003; 85-A (Suppl 3): 96-108.
8. Kawaguchi H, Nakamura K, Tabata Y, Ikada Y, Aoyama I, Anzai J, Nakamura T, Hiyama Y, Tamura M,. Acceleration of fracture healing in nonhuman primates by fibroblast growth factor-2. J Clin Endocrinol Metab 2001; 86: 875-880.
9. Kawaguchi H, Jingushi S, Izumi T, Fukunaga M, Matsushita T, Nakamura T, Mizuno K, Nakamura T, Nakamura K,. Local application of recombinant human fibroblast growth factor-2 on bone repair: a dose-escalation prospective trial on patients with osteotomy. J Orthop Res 2007; 25: 480-487.
10. Kawaguchi H, Oka H, Jingushi S, Izumi T, Fukunaga M, Sato K, Matsushita T, Nakamura K,. A local application of recombinant human fibroblast growth factor 2 for tibial shaft fractures: A randomized, placebo-controlled trial. J Bone Miner Res 2010; 25: 2735-2743.
11. Kawaguchi H, Kurokawa T, Hanada K, Hiyama Y, Tamura M, Ogata E, Matsumoto T,. Stimulation of fracture repair by recombinant human basic fibroblast growth factor in normal and streptozotocin-diabetic rats. Endocrinology 1994; 135: 774-781.
12. Kinard LA, Chu CY, Tabata Y, Kasper FK, Mikos GA,. Bone morphogenetic protein-2 release from composite hydrogels of oligo(poly(ethylene glycaol) fumarate) and gelatin. Pharm Res 2013; 30: 2332-2343.
13. Zhang Q, He QF, Zhang TH, Yu XL, Liu Q, Deng FL,. Improvement in the delivery system of bone morphogenetic protein-2: a new approach to promote bone formation. Biomed Mater 2012; 7: 045002.
14. Nishi N, Matsushita O, Yuube K, Miyanaka H, Okabe A, Wada F,. Collagen-binding growth factors: production and characterization of functional fusion proteins having a collagen-binding domain. Proc Natl Acad Sci U S A 1998; 95: 7018-7023.
15. Uchida K, Matsushita O, Naruse K, Mima T, Nishi N, Hattori S, Ogura T, Inoue G, Tanaka K, Takaso M,. Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase. J Biomed Mater Res A 2013, DOI: 10.1002/jbm.a.34841.
16. Philominathan ST, Matsushita O, Gensure R, Sakon J,. Ca2+-induced linker transformation leads to a compact and rigid collagen-binding domain of Clostridium histolyticum collagenase. FEBS J 2009; 276: 3589-3601.
17. Wilson JJ, Matsushita O, Okabe A, Sakon J,. A bacterial collagen-binding domain with novel calcium-binding motif controls domain orientation. EMBO J 2003; 22: 1743-1752.
18. Matsushita O, Koide T, Kobayashi R, Nagata K, Okabe A,. Substrate recognition by the collagen-binding domain of Clostridium histolyticum class I collagenase. J Biol Chem 2001; 276: 8761-8770.
19. Matsushita O, Jung CM, Minami J, Katayama S, Nishi N, Okabe A,. A study of the collagen-binding domain of a 116-kDa Clostridium histolyticum collagenase. J Biol Chem 1998; 273: 3643-3648.
20. Girish V, Vijayalakshmi A,. Affordable image analysis using NIH Image/ImageJ. Indian J Cancer 2004; 41: 47.
21. Onuma K, Urabe K, Naruse K, Uchida K, Itoman M,. Allogenic serum improves cold preservation of osteochondral allografts. Clin Orthop Relat Res 2012; 470: 2905-2914.
22. Katano M, Naruse K, Uchida K, Mikuni-Takagaki Y, Takaso M, Itoman M, Urabe K,. Low intensity pulsed ultrasound accelerates delayed healing process by reducing the time required for the completion of endochondral ossification in the aged mouse femur fracture model. Exp Anim 2011; 60: 385-395.
23. Uchida K, Urabe K, Naruse K, Kozai Y, Onuma K, Mikuni-Takagaki Y, Kashima I, Ueno M, Sakai R, Itoman M, Takaso M,. Differential age-related bone architecture changes between female and male STR/Ort mice. Exp Anim 2012; 61: 59-66.
24. Ueno M, Urabe K, Naruse K, Uchida K, Minehara H, Yamamoto T, Steck R, Gregory L, Wullschleger ME, Schuetz MA, Itoman M,. Influence of internal fixator stiffness on murine fracture healing: two types of fracture healing lead to two distinct cellular events and FGF-2 expressions. Exp Anim 2011; 60: 79-87.
25. Gayatri R, Sharma KA, Rajaram R, Ramasami T,. Chromium(III)-induced structural charges and self-assembly of collagen. Biochem Bioph Res Co 2001; 283: 229-235.
26. Visser R, Arrabal PM, Becerra J, Rinas U, Cifuentes M,. The effect of an rhBMP-2 absorbable collagen sponge-targeted system on bone formation in vivo. Biomaterials 2009; 30: 2032-2037.
27. Chen W, Shi C, Yi S, Chen B, Zhang W, Fang Z, Wei Z, Jiang S, Sun X, Hou X, Xiao Z, Ye G, Dai J,. Bladder regeneration by collagen scaffolds with collagen binding human basic fibroblast growth factor. J Urol 2010; 183: 2432-2439.
28. Shi C, Chen W, Zhao Y, Chen B, Xiao Z, Wei Z, Hou X, Tang J, Wang Z, Dai J,. Regeneration of full-thickness abdominal wall defects in rats using collagen scaffolds loaded with collagen-binding basic fibroblast growth factor. Biomaterials 2011; 32: 753-759.
29. Rapraeger AC, Krufka A, Olwin BB,. Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation. Science 1991; 252: 1705-1708.
30. Zhao W, Chen B, Li X, Lin H, Sun W, Zhao Y, Wang B, Zhao Y, Han Q, Dai J,. Vascularization and cellularization of collagen scaffolds incorporated with two different collagen-targeting human basic fibroblast growth factors. J Biomed Mater Res A 2007; 82: 630-636.
31. Epstein SE, Fuchs S, Zhou YF, Baffour R, Kornowski R,. Therapeutic interventions for enhancing collateral development by administration of growth factors: basic principles, early results and potential hazards. Cardiovasc Res 2001; 49: 532-542.
32. Unger EF, Goncalves L, Epstein SE, Chew EY, Trapnell CB, Cannon RO, III, Quyyumi AA,. Effects of a single intracoronary injection of basic fibroblast growth factor in stable angina pectoris. Am J Cardiol 2000; 85: 1414-1419.