Müller cells and microglia of the mouse eye react throughout the entire retina in response to the procedure of an intravitreal injection

Advances in Experimental Medicine and Biology

Volumn 801, Issue , 2014, Pages 347-353

  Seitz, Roswitha ^a   Tamm, Ernst R ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Intravitreal injection; Microglia activation; M ller cell gliosis; NMDA

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID; PHOSPHATE BUFFERED SALINE; AMINO ACID RECEPTOR STIMULATING AGENT; N METHYLASPARTIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL TRANSFORMATION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CYTOLOGY; DNA MODIFICATION; IMMUNOHISTOCHEMISTRY; INTRAVITREAL DRUG ADMINISTRATION; MICROGLIA; MOUSE; MUELLER CELL; NERVE CELL STIMULATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; GLIOSIS; INBRED MOUSE STRAIN; MACROGLIA; PATHOLOGY; RETINA; RETINA DISEASE;

ANIMALIA; MUS;

ANIMALS; DISEASE MODELS, ANIMAL; EPENDYMOGLIAL CELLS; EXCITATORY AMINO ACID AGONISTS; GLIOSIS; INTRAVITREAL INJECTIONS; MICE; MICE, INBRED STRAINS; MICROGLIA; N-METHYLASPARTATE; RETINA; RETINAL DISEASES;

EID: 84904788680     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-1-4614-3209-8_44     Document Type: Article

References (12)

1. Seitz R et al (2010) Norrin mediates neuroprotective effects on retinal ganglion cells via activation of the Wnt/beta-catenin signaling pathway and the induction of neuroprotective growth factors in Muller cells. J Neurosci 30(17):5998-6010
2. Seitz R, Tamm ER (2013) N-methyl-D-aspartate (NMDA)-mediated excitotoxic damage: a mouse model of acute retinal ganglion cell damage. Methods Mol Biol 935:99-109
3. Boche D, Perry VH, Nicoll JA (2012) Activation patterns of microglia and their identification in the human brain. Neuropathol Appl Neurobiol 39(1):3-18
4. Bringmann A, Wiedemann P (2012) Muller glial cells in retinal disease. Ophthalmologica 227(1):1-19
5. Humphrey MF et al (1993) A quantitative study of the lateral spread of Muller cell responses to retinal lesions in the rabbit. J Comp Neurol 334(4):545-558
6. Tackenberg MA et al (2009) Muller cell activation, proliferation and migration following laser injury. Mol Vis 15:1886-1896
7. Floyd CL et al (2004) Antagonism of group I metabotropic glutamate receptors and PLC attenuates increases in inositol trisphosphate and reduces reactive gliosis in strain-injured astrocytes. J Neurotrauma 21(2):205-216
8. Karumbaiah L et al (2012) The upregulation of specific interleukin (IL) receptor antagonists and paradoxical enhancement of neuronal apoptosis due to electrode induced strain and brain micromotion. Biomaterials 33(26):5983-5996
9. Miller WJ et al (2009) Mechanically induced reactive gliosis causes ATP-mediated alterations in astrocyte stiffness. J Neurotrauma 26(5):789-797
10. Eder C, Klee R, Heinemann U (1998) Involvement of stretch-activated Cl- channels in ramification of murine microglia. J Neurosci 18(18):7127-7137
11. Ryskamp DA et al (2011) The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells. J Neurosci 31(19):7089-7101
12. Sun D et al (2009) The morphology and spatial arrangement of astrocytes in the optic nerve head of the mouse. J Comp Neurol 516(1):1-19