Rate of decline of antibody titers to pandemic influenza A (H1N1-2009) by hemagglutination inhibition and virus microneutralization assays in a cohort of seroconverting adults in Singapore

BMC Infectious Diseases

Volumn 14, Issue 1, 2014, Pages

  Hsu, Jung P ^a   Zhao, Xiahong ^a   Chen, Mark I Cheng ^a,b   Cook, Alex R ^a   Lee, Vernon ^a,b   Lim, Wei Y ^a   Tan, Linda ^a   Barr, Ian G ^c   Jiang, Lili ^a   Tan, Chyi L ^b   Phoon, Meng C ^a   Cui, Lin ^d   Lin, Raymond ^d   Leo, Yee S ^b   Chow, Vincent T ^a  

^a NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^b TAN TOCK SENG HOSPITAL   (Singapore)

^c WHO COLLABORATING CENTRE FOR REFERENCE AND RESEARCH ON INFLUENZA   (Australia)

^d MINISTRY OF HEALTH   (Singapore)

Author keywords

Declining antibody; Hemagglutination inhibition assay; Microneutralization assay; Pandemic influenza A(H1N1)pdm09; Seroconversion

Indexed keywords

2009 H1N1 INFLUENZA; ADULT; AGE; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HEMAGGLUTINATION INHIBITION; HUMAN; INFECTION RATE; MAJOR CLINICAL STUDY; MALE; PANDEMIC INFLUENZA; QUANTITATIVE ANALYSIS; SEROCONVERSION; SINGAPORE; VIRUS NEUTRALIZATION;

EID: 84904780839     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-14-414     Document Type: Article

References (30)

1. Bloom-Feshbach K, Alonso WJ, Charu V, Tamerius J, Simonsen L, Miller MA, Viboud C. Latitudinal variations in seasonal activity of influenza and respiratory syncytial virus (RSV): a global comparative review. PLoS One 2013, 8(2):e54445.
2. Lee VJ, Yap J, Ong JB, Chan KP, Lin RT, Chan SP, Goh KT, Leo YS, Chen MI. Influenza excess mortality from 1950-2000 in tropical Singapore. PLoS One 2009, 4(12):e8096.
3. Trauer JM, Bandaranayake D, Booy R, Chen MI, Cretikos M, Dowse GK, Dwyer DE, Greenberg ME, Huang QS, Khandaker G, Kok J, Laurie KL, Lee VJ, McVernon J, Walter S, Markey PG. Seroepidemiologic effects of influenza A(H1N1)pdm09 in Australia, New Zealand, and Singapore. Emerg Infect Dis 2013, 19(1):92-101.
4. Chen MI, Cook AR, Lim WY, Lin R, Cui L, Barr IG, Kelso A, Chow VT, Leo YS, Hsu JP, Shaw R, Chew S, Yap JK, Phoon MC, Koh HW, Zheng H, Tan L, Lee VJ. Factors influencing infection by pandemic influenza A(H1N1)pdm09 over three epidemic waves in Singapore. Influenza Other Respir Viruses 2013, 7(6):1380-1389.
5. Presanis AM, Pebody RG, Paterson BJ, Tom BD, Birrell PJ, Charlett A, Lipsitch M, De Angelis D. Changes in severity of 2009 pandemic A/H1N1 influenza in England: a Bayesian evidence synthesis. BMJ 2011, 343:d5408.
6. Win MK, Chen MI, Barkham T, Lin C, Tan A, Lin R, Leo YS. Influenza disease burden in adults by subtypes following the initial epidemic of pandemic H1N1 in Singapore. Influenza Other Respi Viruses 2011, 5(6):e563-e567.
7. Mytton OT, Rutter PD, Donaldson LJ. Influenza A(H1N1)pdm09 in England, 2009 to 2011: a greater burden of severe illness in the year after the pandemic than in the pandemic year. Euro Surveill 2012, 17(14).
8. Brown EG. Influenza virus genetics. Biomed Pharmacother 2000, 54(4):196-209.
9. Truscott J, Fraser C, Cauchemez S, Meeyai A, Hinsley W, Donnelly CA, Ghani A, Ferguson N. Essential epidemiological mechanisms underpinning the transmission dynamics of seasonal influenza. J R Soc Interface 2012, 9(67):304-312.
10. Wang M, Yuan J, Li T, Liu Y, Wu J, Di B, Chen X, Xu X, Lu E, Li K, Wu Y, He P, Wang Y, Liu J. Antibody dynamics of 2009 influenza A (H1N1) virus in infected patients and vaccinated people in China. PLoS One 2011, 6(2):e16809.
11. Chan KH, To KK, Hung IF, Zhang AJ, Chan JF, Cheng VC, Tse H, Che XY, Chen H, Yuen KY. Differences in antibody responses of individuals with natural infection and those vaccinated against pandemic H1N1 2009 influenza. Clin Vaccine Immunol 2011, 18(5):867-873.
12. Al-Khayatt R, Jennings R, Potter CW. Interpretation of responses and protective levels of antibody against attenuated influenza A viruses using single radial haemolysis. J Hyg 1984, 93(2):301-312.
13. Papenburg J, Baz M, Hamelin ME, Rheaume C, Carbonneau J, Ouakki M, Rouleau I, De Serres G, Boivin G. Evaluation of serological diagnostic methods for the 2009 pandemic influenza A (H1N1) virus. Clin Vaccine Immunol 2011, 18(3):520-522.
14. Chen MI, Lee VJ, Lim WY, Barr IG, Lin RT, Koh GC, Yap J, Cui L, Cook AR, Laurie K, Tan LW, Tan BH, Loh J, Shaw R, Durrant C, Chow VT, Kelso A, Chia KS, Leo YS. 2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore. JAMA 2010, 303(14):1383-1391.
15. Hayward AC, Fragaszy EB, Bermingham A, Wang L, Copas A, Edmunds WJ, Ferguson N, Goonetilleke N, Harvey G, Kovar J, Lim MS, McMichael A, Millett ER, Nguyen-Van-Tam JS, Nazareth I, Pebody R, Tabassum F, Watson JM, Wurie FB, Johnson AM, Zambon M. Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study. Lancet Respir Med 2014, 2(6):445-454.
16. Horby P, Le Mai Q, Fox A, Thai PQ, Thi Thu Yen N, Le Thanh T, Le Khanh HN, Duong TN, Thoang DD, Farrar J, Wolbers M, Hien NT. The epidemiology of interpandemic and pandemic influenza in Vietnam, 2007-2010: the Ha Nam household cohort study I. Am J Epidemiol 2012, 175(10):1062-1074.
17. Riley S, Kwok KO, Wu KM, Ning DY, Cowling BJ, Wu JT, Ho LM, Tsang T, Lo SV, Chu DK, Ma ES, Peiris JS. Epidemiological characteristics of 2009 (H1N1) pandemic influenza based on paired sera from a longitudinal community cohort Study. PLoS Med 2011, 8(6):e1000442.
18. Kendal AP, Pereira MS, Skehel JJ. Concepts and procedures for laboratory-based influenza surveillance 1982, Geneva: World Health Organization.
19. Lee VJ, Tay JK, Chen MI, Phoon MC, Xie ML, Wu Y, Lee CX, Yap J, Sakharkar KR, Sakharkar MK, Lin RT, Cui L, Kelly PM, Leo YS, Tan YJ, Chow VT. Inactivated trivalent seasonal influenza vaccine induces limited cross-reactive neutralizing antibody responses against 2009 pandemic and 1934 PR8 H1N1 strains. Vaccine 2010, 28(42):6852-6857.
20. Wood JM, Major D, Heath A, Newman RW, Hoschler K, Stephenson I, Clark T, Katz JM, Zambon MC. Reproducibility of serology assays for pandemic influenza H1N1: collaborative study to evaluate a candidate WHO International Standard. Vaccine 2012, 30(2):210-217.
21. Ong JBS, Chen MIC, Cook AR, Lee HC, Lee VJ, Lin RTP, Tambyah PA, Goh LG. Real-Time Epidemic Monitoring and Forecasting of H1N1-2009 Using Influenza-Like Illness from General Practice and Family Doctor Clinics in Singapore. PLoS One 2010, 5(4):e10036-e10036.
22. Lee VJ, Chen MI, Chan SP, Wong CS, Cutter J, Goh KT, Tambyah PA. Influenza pandemics in Singapore, a tropical, globally connected city. Emerg Infect Dis 2007, 13(7):1052-1057.
23. Couch RB, Atmar RL, Franco LM, Quarles JM, Wells J, Arden N, Nino D, Belmont JW. Antibody correlates and predictors of immunity to naturally occurring influenza in humans and the importance of antibody to the neuraminidase. J Infect Dis 2013, 207(6):974-981.
24. Chen MI, Barr IG, Koh GC, Lee VJ, Lee CP, Shaw R, Lin C, Yap J, Cook AR, Tan BH, Loh JP, Barkham T, Chow VT, Lin RT, Leo YS. Serological response in RT-PCR confirmed H1N1-2009 influenza a by hemagglutination inhibition and virus neutralization assays: an observational study. PLoS One 2010, 5(8):e12474.
25. Weinberger B, Grubeck-Loebenstein B. Vaccines for the elderly. Clin Microbiol Infect 2012, 18(Suppl 5):100-108.
26. Simonsen L, Taylor RJ, Viboud C, Miller MA, Jackson LA. Mortality benefits of influenza vaccination in elderly people: an ongoing controversy. Lancet Infect Dis 2007, 7(10):658-666.
27. Osterholm MT, Kelley NS, Sommer A, Belongia EA. Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis. Lancet Infect Dis 2012, 12(1):36-44.
28. Hsu JP, Phoon MC, Koh GC, Chen MI, Lee VJ, Wu Y, Xie ML, Cheong A, Leo YS, Chow VT. Comparison of neutralizing antibody and cell-mediated immune responses to pandemic H1N1 2009 influenza virus before and after H1N1 2009 influenza vaccination of elderly subjects and healthcare workers. Int J Infect Dis 2012, 16(8):e621-e627.
29. Greenbaum JA, Kotturi MF, Kim Y, Oseroff C, Vaughan K, Salimi N, Vita R, Ponomarenko J, Scheuermann RH, Sette A, Peters B. Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population. Proc Natl Acad Sci U S A 2009, 106(48):20365-20370.
30. Kurupati RK, Kannan S, Xiang ZQ, Doyle S, Ratcliffe S, Schmader KE, Ertl HC. B cell responses to the 2011/12-influenza vaccine in the aged. Aging 2013, 5(3):209-226.