Inhibition of phosphatase and tensin homologue (PTEN) in human ovary in vitro results in increased activation of primordial follicles but compromises development of growing follicles

Molecular Human Reproduction

Volumn 20, Issue 8, 2014, Pages 736-744

  McLaughlin, Marie ^a   Innell, Hazel L ^b   Anderson, Richard A ^b   Telfer, Evelyn E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Follicle; Human; In vitro; Ovary; PTEN

Indexed keywords

ACTIVIN A; DIPOTASSIUM BISPEROXO(5 HYDROXYPYRIDINE 2 CARBOXYL)OXOVANADATE; ESTERASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RECOMBINANT CYTOKINE; TISSUE CULTURE MEDIUM; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; BISPEROXOVANADIUM; PTEN PROTEIN, HUMAN; VANADIUM DERIVATIVE;

ADULT; ARTICLE; BIOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INCUBATION TIME; MICROSCOPY; ORGAN GROWTH; OVARY FOLLICLE; OVARY FOLLICLE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN TRANSPORT; SURVIVAL; TISSUE CULTURE; TISSUE FIXATION; TISSUE SURVIVAL; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MIDDLE AGED; OVARY; TISSUE CULTURE TECHNIQUE; YOUNG ADULT;

ADULT; BLOTTING, WESTERN; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; OVARIAN FOLLICLE; OVARY; PTEN PHOSPHOHYDROLASE; TISSUE CULTURE TECHNIQUES; VANADIUM COMPOUNDS; YOUNG ADULT;

EID: 84904764685     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gau037     Document Type: Article

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