Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells

Cancer Letters

Volumn 351, Issue 2, 2014, Pages 242-251

  Qian, Yanrong ^a   Wang, Xuan ^a   Liu, Yi ^a   Li, Yunsheng ^a   Colvin, Robert A ^a   Tong, Lingying ^a   Wu, Shiyong ^a   Chen, Xiaozhuo ^a,b  

^a OHIO UNIVERSITY   (United States)

^b OHIO UNIVERSITY   (United States)

Author keywords

Cancer metabolism; Kras; Nonhydrolyzable fluorescent ATP; Receptor tyrosine kinase; Warburg effect

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; CYCLOHEXIMIDE; DACTINOMYCIN; DEXTRAN; PAZOPANIB; SUNITINIB; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL LINE; CANCER RESISTANCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GLYCOLYSIS; HUMAN; HUMAN CELL; INTERNALIZATION; METABOLIC STRESS; MOLECULAR WEIGHT; OXIDATIVE PHOSPHORYLATION; PHARMACOLOGICAL BLOCKING; PINOCYTOSIS; PRIORITY JOURNAL; CELL GROWTH; DOSE RESPONSE; DRUG RESISTANCE; EXTRACELLULAR SPACE; LUNG NEOPLASMS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; ANTINEOPLASTIC AGENTS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; EXTRACELLULAR SPACE; GLYCOLYSIS; HUMANS; LUNG NEOPLASMS; OXIDATIVE PHOSPHORYLATION; PHOSPHORYLATION; PINOCYTOSIS; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES;

EID: 84904758667     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.06.008     Document Type: Article

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