메뉴 건너뛰기




Volumn 60, Issue 2, 2014, Pages 458-460

Reversal of vasohibin-driven negative feedback loop of vascular endothelial growth factor/angiogenesis axis promises a novel antifibrotic therapeutic strategy for liver diseases

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIFIBROTIC AGENT; BEVACIZUMAB; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR RECEPTOR 1; PLATELET DERIVED GROWTH FACTOR; SORAFENIB; SUNITINIB; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VASCULOTROPIN; VASOHIBIN;

EID: 84904757023     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27061     Document Type: Article
Times cited : (9)

References (19)
  • 1
    • 84875892969 scopus 로고    scopus 로고
    • Vasohibin 2 is transcriptionally activated and promotes angiogenesis in hepatocellular carcinoma
    • Xue X, Gao W, Sun B, Xu Y, Han B, Wang F, et al. Vasohibin 2 is transcriptionally activated and promotes angiogenesis in hepatocellular carcinoma. Oncogene 2013;32:1724-1734.
    • (2013) Oncogene , vol.32 , pp. 1724-1734
    • Xue, X.1    Gao, W.2    Sun, B.3    Xu, Y.4    Han, B.5    Wang, F.6
  • 2
    • 84867986488 scopus 로고    scopus 로고
    • Upregulation of vasohibin-1 expression withangiogenesis and poor prognosis of hepatocellular carcinoma after curativesurgery
    • Wang Q, Tian X, Zhang C, Wang Q. Upregulation of vasohibin-1 expression withangiogenesis and poor prognosis of hepatocellular carcinoma after curativesurgery. Med Oncol 2012;29:2727-2736.
    • (2012) Med Oncol , vol.29 , pp. 2727-2736
    • Wang, Q.1    Tian, X.2    Zhang, C.3    Wang, Q.4
  • 4
    • 84904724134 scopus 로고    scopus 로고
    • Disruption of negative feedback loop between vasohibin-1 and VEGF decreases portal pressure, angiogenesis and fibrosis in cirrhotic rats
    • Coch L, Mejias M, Berzigotti A, Garcia-Pras E, Gallego J, Bosch J, et al. Disruption of negative feedback loop between vasohibin-1 and VEGF decreases portal pressure, angiogenesis and fibrosis in cirrhotic rats. Hepatology 2014;60:633-647.
    • (2014) Hepatology , vol.60 , pp. 633-647
    • Coch, L.1    Mejias, M.2    Berzigotti, A.3    Garcia-Pras, E.4    Gallego, J.5    Bosch, J.6
  • 5
    • 9644262535 scopus 로고    scopus 로고
    • Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis
    • Watanabe K, Hasegawa Y, Yamashita H, Shimizu K, Ding Y, Abe M, et al. Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis. J Clin Invest 2004;114:898-907.
    • (2004) J Clin Invest , vol.114 , pp. 898-907
    • Watanabe, K.1    Hasegawa, Y.2    Yamashita, H.3    Shimizu, K.4    Ding, Y.5    Abe, M.6
  • 6
    • 79954466760 scopus 로고    scopus 로고
    • Amelioration of renal alterations in obese type 2 diabetic mice by vasohibin-1, a negative feedback regulator of angiogenesis
    • Saito D, Maeshima Y, Nasu T, Yamasaki H, Tanabe K, Sugiyama H, et al. Amelioration of renal alterations in obese type 2 diabetic mice by vasohibin-1, a negative feedback regulator of angiogenesis. Am J Physiol Renal Physiol 2011;300:F873-F886.
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Saito, D.1    Maeshima, Y.2    Nasu, T.3    Yamasaki, H.4    Tanabe, K.5    Sugiyama, H.6
  • 7
    • 77957328518 scopus 로고    scopus 로고
    • Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: new targets for the treatment of portal hypertension?
    • Thabut D, Shah V. Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: new targets for the treatment of portal hypertension? J Hepatol 2010;53:976-980.
    • (2010) J Hepatol , vol.53 , pp. 976-980
    • Thabut, D.1    Shah, V.2
  • 8
    • 0031778206 scopus 로고    scopus 로고
    • Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver
    • El-Assal ON, Yamanoi A, Soda Y, Yamaguchi M, Igarashi M, Yamamoto A, et al. Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver. Hepatology 1998;27:1554-1562.
    • (1998) Hepatology , vol.27 , pp. 1554-1562
    • El-Assal, O.N.1    Yamanoi, A.2    Soda, Y.3    Yamaguchi, M.4    Igarashi, M.5    Yamamoto, A.6
  • 9
    • 84904741716 scopus 로고    scopus 로고
    • Dufour JF, Clavien PA, eds. Berlin: Springer-Verlag;
    • Dufour JF, Clavien PA, eds. Signaling Pathways in Liver Diseases. Berlin: Springer-Verlag; 2010:41-68.
    • (2010) Signaling Pathways in Liver Diseases , pp. 41-68
  • 10
    • 0034822702 scopus 로고    scopus 로고
    • Identication of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression
    • Shackel NA, McGuinness P, Abbott C, Gorrell M, McCaughan G. Identication of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression. Gut 2001;49:567-576.
    • (2001) Gut , vol.49 , pp. 567-576
    • Shackel, N.A.1    McGuinness, P.2    Abbott, C.3    Gorrell, M.4    McCaughan, G.5
  • 11
    • 84904743772 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration. FDA Commissioner announces Avastin decision-drug not shown to be safe and effective in breast cancer patients. Available at: Accessed February 21, 2014.
    • U.S. Food and Drug Administration. FDA Commissioner announces Avastin decision-drug not shown to be safe and effective in breast cancer patients. 2011. Available at: www.fda.gov/downloads/NewsEvents/Newsroom/UCM280546.pdf. Accessed February 21, 2014.
    • (2011)
  • 13
    • 84904726718 scopus 로고    scopus 로고
    • Everolimus is a potent inhibitor of activated hepatic stellate cell functions in vitro and in vivo, while demonstrating anti-angiogenic activities
    • Nov 28. [Epub ahead of print].
    • Piguet AC, Majumder S, Balaguru UM, Manjunathan R, Saran U, Chatterjee S, Dufour JF. Everolimus is a potent inhibitor of activated hepatic stellate cell functions in vitro and in vivo, while demonstrating anti-angiogenic activities. Clin Sci (Lond) 2013 Nov 28. [Epub ahead of print].
    • (2013) Clin Sci (Lond)
    • Piguet, A.C.1    Majumder, S.2    Balaguru, U.M.3    Manjunathan, R.4    Saran, U.5    Chatterjee, S.6    Dufour, J.F.7
  • 14
    • 37749049919 scopus 로고    scopus 로고
    • Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats
    • Tugues S, Fernandez-Varo G, Muñoz-Luque J, Ros J, Arroyo V, Rodés J, et al. Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats. Hepatology 2007;46:1919-1926.
    • (2007) Hepatology , vol.46 , pp. 1919-1926
    • Tugues, S.1    Fernandez-Varo, G.2    Muñoz-Luque, J.3    Ros, J.4    Arroyo, V.5    Rodés, J.6
  • 15
    • 54449083925 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma
    • Llovet JM, Bruix J. Molecular targeted therapies in hepatocellular carcinoma. Hepatology 2008;48:1312-1327.
    • (2008) Hepatology , vol.48 , pp. 1312-1327
    • Llovet, J.M.1    Bruix, J.2
  • 16
    • 84883411552 scopus 로고    scopus 로고
    • Bevacizumab attenuates hepatic fibrosis in rats by inhibiting activation of hepatic stellate cells
    • Huang Y, Feng H, Kan T, Huang B, Zhang M, Li Y, et al. Bevacizumab attenuates hepatic fibrosis in rats by inhibiting activation of hepatic stellate cells. PLoS One 2013;8:e73492.
    • (2013) PLoS One , vol.8
    • Huang, Y.1    Feng, H.2    Kan, T.3    Huang, B.4    Zhang, M.5    Li, Y.6
  • 18
    • 84856390541 scopus 로고    scopus 로고
    • Hypoxia and hypoxia inducible factors: diverse roles in liver diseases
    • Nath B, Szabo G. Hypoxia and hypoxia inducible factors: diverse roles in liver diseases. Hepatology 2012;55:622-633.
    • (2012) Hepatology , vol.55 , pp. 622-633
    • Nath, B.1    Szabo, G.2
  • 19
    • 84859269337 scopus 로고    scopus 로고
    • Vasohibin induces prolyl hydroxylase-mediated degradation of hypoxia-inducible factor-1α in human umbilical vein endothelial cells
    • Kozako T, Matsumoto N, Kuramoto Y, Sakata A, Motonagare R, Aikawa A, et al. Vasohibin induces prolyl hydroxylase-mediated degradation of hypoxia-inducible factor-1α in human umbilical vein endothelial cells. FEBS Lett 2012;586:1067-1072.
    • (2012) FEBS Lett , vol.586 , pp. 1067-1072
    • Kozako, T.1    Matsumoto, N.2    Kuramoto, Y.3    Sakata, A.4    Motonagare, R.5    Aikawa, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.