Type 2 diabetes-related genetic risk scores associated with variations in fasting plasma glucose and development of impaired glucose homeostasis in the prospective DESIR study

Diabetologia

Volumn 57, Issue 8, 2014, Pages 1601-1610

  Vaxillaire, Martine ^a,b,c   Yengo, Loïc ^a,b,c   Lobbens, Stéphane ^a,b,c   Rocheleau, Ghislain ^a,b,c   Eury, Elodie ^a,b,c   Lantieri, Olivier ^d   Marre, Michel ^e,f   Balkau, Beverley ^g,h   Bonnefond, Amélie ^a,b,c   Froguel, Philippe ^a,b,c,i  

^a France   (France)

^b INSTITUT PASTEUR DE LILLE   (France)

^c UNIV LILLE   (France)

^d IRSA   (France)

^e BICHAT HOSPITAL   (France)

^f CENTRE DE RECHERCHE DES CORDELIERS   (France)

^g CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^h UNIVERSITÉ PARIS SACLAY   (France)

ⁱ HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

DESIR; Genotype risk score; Hyperglycaemia; Impaired fasting glucose; Incidence analysis; Metabochip; Quantitative metabolic trait; Type 2 diabetes

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; GLUCOSE BLOOD LEVEL;

ADULT; AGE; AGED; ALLELE; ARTICLE; BODY MASS; DIET RESTRICTION; FAMILY HISTORY; FEMALE; GENDER; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC RISK SCORE; GENETIC SELECTION; GENOTYPE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HUMAN; HYPERGLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PHYSICAL ACTIVITY; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; ANALYSIS; BLOOD; CAUCASIAN; GENETIC PREDISPOSITION; GENETICS; HOMEOSTASIS; MIDDLE AGED; PROSPECTIVE STUDY;

ADULT; AGED; ALLELES; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HOMEOSTASIS; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES;

EID: 84904746615     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3277-x     Document Type: Article

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