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Volumn 44, Issue 8, 2014, Pages 888-896

Therapeutic effects of the direct renin inhibitor, aliskiren, on non-alcoholic steatohepatitis in fatty liver Shionogi ob/ob male mice

Author keywords

Direct renin inhibitors; Liver fibrosis; Liver steatosis; Non alcoholic steatohepatitis; Oxidative stress

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; ALISKIREN; ALPHA SMOOTH MUSCLE ACTIN; CONNECTIVE TISSUE GROWTH FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; PLACEBO; RNA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84904738043     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/hepr.12186     Document Type: Article
Times cited : (16)

References (26)
  • 1
    • 79955689492 scopus 로고    scopus 로고
    • An overview of nonalcoholic steatohepatitis: past, present and future directions
    • Pascale A, Pais R, Ratziu V. An overview of nonalcoholic steatohepatitis: past, present and future directions. J Gastrointestin Liver Dis 2010; 19: 415-423.
    • (2010) J Gastrointestin Liver Dis , vol.19 , pp. 415-423
    • Pascale, A.1    Pais, R.2    Ratziu, V.3
  • 2
    • 78651352067 scopus 로고    scopus 로고
    • Prevalence, gender, ethnic variations, and prognosis of NASH
    • Hashimoto E, Tokushige K. Prevalence, gender, ethnic variations, and prognosis of NASH. J Gastroenterol 2011; 46 (Suppl 1): 63-69.
    • (2011) J Gastroenterol , vol.46 , Issue.Suppl 1 , pp. 63-69
    • Hashimoto, E.1    Tokushige, K.2
  • 3
    • 39849099669 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease and the metabolic syndrome: an update
    • Rector RS, Thyfault JP, Wei Y, Ibdah JA. Non-alcoholic fatty liver disease and the metabolic syndrome: an update. World J Gastroenterol 2008; 14: 185-192.
    • (2008) World J Gastroenterol , vol.14 , pp. 185-192
    • Rector, R.S.1    Thyfault, J.P.2    Wei, Y.3    Ibdah, J.A.4
  • 4
    • 65449118734 scopus 로고    scopus 로고
    • The rennin angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress
    • Marique C, Lastra G, Gardner M, Sowers JR. The rennin angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress. Med Clin North Am 2009; 93: 569-582.
    • (2009) Med Clin North Am , vol.93 , pp. 569-582
    • Marique, C.1    Lastra, G.2    Gardner, M.3    Sowers, J.R.4
  • 5
    • 77953713390 scopus 로고    scopus 로고
    • The renin angiotensin system and the metabolic syndrome
    • De Kloet AD, Krause EG, Woods SC. The renin angiotensin system and the metabolic syndrome. Physiol Behav 2010; 100: 525-534.
    • (2010) Physiol Behav , vol.100 , pp. 525-534
    • De Kloet, A.D.1    Krause, E.G.2    Woods, S.C.3
  • 7
    • 33750988751 scopus 로고    scopus 로고
    • Preventive and therapeutic effects of angiotensin II type 1 receptor blocker on hepatic fibrosis induced by bile duct ligation in rats
    • Ueki M, Koda M, Yamamoto S, Matsunaga Y, Murawaki Y. Preventive and therapeutic effects of angiotensin II type 1 receptor blocker on hepatic fibrosis induced by bile duct ligation in rats. J Gastroenterol 2006; 41: 996-1004.
    • (2006) J Gastroenterol , vol.41 , pp. 996-1004
    • Ueki, M.1    Koda, M.2    Yamamoto, S.3    Matsunaga, Y.4    Murawaki, Y.5
  • 8
    • 84861464460 scopus 로고    scopus 로고
    • Therapeutic effects of angiotensin II type 1 receptor blocker, irbesartan, on non-alcoholic steatohepatitis using FLS-ob/ob male mice
    • Kato J, Koda M, Kishina M etal. Therapeutic effects of angiotensin II type 1 receptor blocker, irbesartan, on non-alcoholic steatohepatitis using FLS-ob/ob male mice. Int J Mol Med 2012; 30: 107-113.
    • (2012) Int J Mol Med , vol.30 , pp. 107-113
    • Kato, J.1    Koda, M.2    Kishina, M.3
  • 9
    • 70350511929 scopus 로고    scopus 로고
    • Effect of an angiotensin- II type 1 receptor blocker, candesartan on hepatic fibrosis in chronic hepatitis C : a prospective study
    • Ueki M, Koda M, Shimizu T, Mitsuda A, Yamamoto T, Murawaki Y. Effect of an angiotensin- II type 1 receptor blocker, candesartan on hepatic fibrosis in chronic hepatitis C : a prospective study. Hepatogastroenterology 2009; 56: 1100-1104.
    • (2009) Hepatogastroenterology , vol.56 , pp. 1100-1104
    • Ueki, M.1    Koda, M.2    Shimizu, T.3    Mitsuda, A.4    Yamamoto, T.5    Murawaki, Y.6
  • 10
    • 38149078717 scopus 로고    scopus 로고
    • Inhibition of the renin-angiotensin system attenuates the development of liver fibrosis and oxidative stress in rats
    • El-Demerdash E, Salam OMA, El-Batran SA, Abdallah HM, Shaffie NM. Inhibition of the renin-angiotensin system attenuates the development of liver fibrosis and oxidative stress in rats. Clin Exp Pharmacol Physiol 2008; 35: 159-167.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 159-167
    • El-Demerdash, E.1    Salam, O.M.A.2    El-Batran, S.A.3    Abdallah, H.M.4    Shaffie, N.M.5
  • 11
    • 69249214117 scopus 로고    scopus 로고
    • Preventative and therapeutic effects of perindopril on hepatic fibrosis induced by bile duct ligation in rats
    • Ueki M, Koda M, Matono T, Sugihara T, Maeda K, Murawaki Y. Preventative and therapeutic effects of perindopril on hepatic fibrosis induced by bile duct ligation in rats. Mol Med Rep 2009; 2: 857-864.
    • (2009) Mol Med Rep , vol.2 , pp. 857-864
    • Ueki, M.1    Koda, M.2    Matono, T.3    Sugihara, T.4    Maeda, K.5    Murawaki, Y.6
  • 12
    • 34250323865 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blocker inhibits fibrosis in rat nonalcoholic steatohepatitis
    • Hirose A, Ono M, Saibara T etal. Angiotensin II type 1 receptor blocker inhibits fibrosis in rat nonalcoholic steatohepatitis. Hepatology 2007; 45: 1375-1381.
    • (2007) Hepatology , vol.45 , pp. 1375-1381
    • Hirose, A.1    Ono, M.2    Saibara, T.3
  • 13
    • 46549089538 scopus 로고    scopus 로고
    • Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects
    • Kurita S, Takamura T, Ota T etal. Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects. Eur J Pharmacol 2008; 588: 316-324.
    • (2008) Eur J Pharmacol , vol.588 , pp. 316-324
    • Kurita, S.1    Takamura, T.2    Ota, T.3
  • 14
    • 78349289577 scopus 로고    scopus 로고
    • A reduction of unilateral ureteral obstruction-induced renal fibrosis by a therapy combining valsartan with aliskiren
    • Wu WP, Chang CH, Chiu YT etal. A reduction of unilateral ureteral obstruction-induced renal fibrosis by a therapy combining valsartan with aliskiren. Am J Physiol 2010; 299: 929-941.
    • (2010) Am J Physiol , vol.299 , pp. 929-941
    • Wu, W.P.1    Chang, C.H.2    Chiu, Y.T.3
  • 15
    • 13044256397 scopus 로고    scopus 로고
    • The FLS mouse: a new inbred strain with spontaneous fatty liver
    • Soga M, Kishimoto Y, Kawaguchi J etal. The FLS mouse: a new inbred strain with spontaneous fatty liver. Lab Anim Sci 1999; 49: 269-275.
    • (1999) Lab Anim Sci , vol.49 , pp. 269-275
    • Soga, M.1    Kishimoto, Y.2    Kawaguchi, J.3
  • 17
    • 84876969186 scopus 로고    scopus 로고
    • Fatty liver Shionogi-ob/ob mouse: a new candidate for a non-alcoholic steatohepatitis model
    • Sugihara T, Koda M, Kishina M etal. Fatty liver Shionogi-ob/ob mouse: a new candidate for a non-alcoholic steatohepatitis model. Hepatol Res 2013; 43: 547-556.
    • (2013) Hepatol Res , vol.43 , pp. 547-556
    • Sugihara, T.1    Koda, M.2    Kishina, M.3
  • 18
    • 49649110937 scopus 로고    scopus 로고
    • Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
    • Wouters K, Gorp PJV, Bieghs V etal. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology 2008; 48: 474-486.
    • (2008) Hepatology , vol.48 , pp. 474-486
    • Wouters, K.1    Gorp, P.J.V.2    Bieghs, V.3
  • 19
    • 80053612479 scopus 로고    scopus 로고
    • Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis
    • Rooyen DMV, Larter CZ, Haigh WG etal. Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis. Gastroenterology 2011; 141: 1393-1403.
    • (2011) Gastroenterology , vol.141 , pp. 1393-1403
    • Rooyen, D.M.V.1    Larter, C.Z.2    Haigh, W.G.3
  • 20
    • 84886826434 scopus 로고    scopus 로고
    • Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model
    • Epub ahead of print].
    • Aihara Y, Yoshiji H, Noguchi R etal. Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model. Hepatol Res 2013; [Epub ahead of print].
    • (2013) Hepatol Res
    • Aihara, Y.1    Yoshiji, H.2    Noguchi, R.3
  • 22
    • 84862235241 scopus 로고    scopus 로고
    • Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells
    • Luo X, Yang Y, Shen T etal. Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells. Nutr Metab (Lond) 2012; 9: 34.
    • (2012) Nutr Metab (Lond) , vol.9 , pp. 34
    • Luo, X.1    Yang, Y.2    Shen, T.3
  • 23
    • 77951146612 scopus 로고    scopus 로고
    • C-C chemokine receptor 2(CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis
    • Obstfeld AE, Sugaru E, Thearle M etal. C-C chemokine receptor 2(CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis. Diabetes 2010; 59: 916-925.
    • (2010) Diabetes , vol.59 , pp. 916-925
    • Obstfeld, A.E.1    Sugaru, E.2    Thearle, M.3
  • 24
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • Kanda H, Tateya S, Tamori Y etal. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 2006; 116: 1494-1505.
    • (2006) J Clin Invest , vol.116 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3
  • 25
    • 58149328554 scopus 로고    scopus 로고
    • Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis
    • Singh VP, Le B, Khode R, Baker KM, Kumar R. Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis. Diabetes 2008; 57: 3297-3306.
    • (2008) Diabetes , vol.57 , pp. 3297-3306
    • Singh, V.P.1    Le, B.2    Khode, R.3    Baker, K.M.4    Kumar, R.5
  • 26
    • 84855457188 scopus 로고    scopus 로고
    • The renin-angiotensin system: a link between obesity, inflammation and insulin resistance
    • Kalupahana NS, Moustaid-Moussa N. The renin-angiotensin system: a link between obesity, inflammation and insulin resistance. Obes Rev 2012; 13: 136-149.
    • (2012) Obes Rev , vol.13 , pp. 136-149
    • Kalupahana, N.S.1    Moustaid-Moussa, N.2


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