Insulin resistance, steatohepatitis, and hepatocellular carcinoma in a new congenic strain of fatty liver shionogi (FLS) mice with the Lepob gene

Experimental Animals

Volumn 59, Issue 4, 2010, Pages 407-419

  Soga, Masahiko ^a   Hashimoto, Setsuko ^a   Kishimoto, Yoshio ^a   Hirasawa, Tsutomu ^a   Makino, Susumu ^a,b   Inagaki, Shuichiro ^a  

^a SHIONOGI AND CO LTD   (Japan)

^b Bioscience Center of KAC Co Ltd   (Japan)

Author keywords

Hepatocellular carcinoma; Insulin resistance; Nonalcoholic steatohepsatitis; Obesity

Indexed keywords

GLUCOSE; INSULIN; LEPTIN; LIPID; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACKCROSSING; C57BL 6 MOUSE; CELL INFILTRATION; CONGENIC STRAIN; CONTROLLED STUDY; FEMALE; GLUCOSURIA; HEPATITIS; HYPERINSULINEMIA; HYPERLIPIDEMIA; HYPERPHAGIA; INSULIN RESISTANCE; LIPID STORAGE; LIVER ADENOMA; LIVER CELL CARCINOMA; MALE; METABOLIC DISORDER; MONONUCLEAR CELL; MOUSE; MULTIPLE CANCER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; FATTY LIVER; GENE EXPRESSION; GENETICS; GLUCOSE TOLERANCE TEST; LIVER; LIVER CELL; LIVER TUMOR; METABOLISM; PATHOLOGY;

ANIMALIA; MUS;

ADENOMA, LIVER CELL; ANIMALS; CARCINOMA, HEPATOCELLULAR; DIABETES MELLITUS, TYPE 2; FATTY LIVER; FEMALE; GENE EXPRESSION; GLUCOSE TOLERANCE TEST; GLYCOSURIA; HEPATOCYTES; HYPERLIPIDEMIAS; INSULIN RESISTANCE; LEPTIN; LIPIDS; LIVER; LIVER NEOPLASMS; MALE; MICE; MICE, CONGENIC; MICE, INBRED C57BL; OBESITY; RNA, MESSENGER;

EID: 77957234569     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.59.407     Document Type: Article

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