메뉴 건너뛰기




Volumn 12, Issue 4, 2014, Pages 262-269

Sequential targeted therapy after pazopanib therapy in patients with metastatic renal cell cancer: Efficacy and toxicity

Author keywords

mTOR inhibitor; Pazopanib; Renal cell carcinoma; Sequential therapy; VEGF targeted therapy

Indexed keywords

BEVACIZUMAB; CEDIRANIB; EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PAZOPANIB; SORAFENIB; SUNITINIB; ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; INDOLE DERIVATIVE; MONOCLONAL ANTIBODY; MTOR PROTEIN, HUMAN; NICOTINAMIDE; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; RAPAMYCIN; SULFONAMIDE; TARGET OF RAPAMYCIN KINASE; TEMSIROLIMUS; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

EID: 84904723196     PISSN: 15587673     EISSN: 19380682     Source Type: Journal    
DOI: 10.1016/j.clgc.2014.03.002     Document Type: Article
Times cited : (10)

References (31)
  • 2
    • 0344442746 scopus 로고    scopus 로고
    • Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease
    • N.K. Janzen, H.L. Kim, R.A. Figlin, and A.S. Belldegrun Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease Urol Clin N Am 30 2003 843 852
    • (2003) Urol Clin N Am , vol.30 , pp. 843-852
    • Janzen, N.K.1    Kim, H.L.2    Figlin, R.A.3    Belldegrun, A.S.4
  • 3
    • 77955618680 scopus 로고    scopus 로고
    • Updates on novel therapies for metastatic renal cell carcinoma
    • K.D. Courtney, and T.K. Choueiri Updates on novel therapies for metastatic renal cell carcinoma Ther Adv Med Oncol 2 2010 209 219
    • (2010) Ther Adv Med Oncol , vol.2 , pp. 209-219
    • Courtney, K.D.1    Choueiri, T.K.2
  • 4
    • 4644363095 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor gene and kidney cancer
    • W.G. Kaelin Jr. The von Hippel-Lindau tumor suppressor gene and kidney cancer Clin Cancer Res 10 2004 6290S 6295S
    • (2004) Clin Cancer Res , vol.10
    • Kaelin, Jr.W.G.1
  • 5
    • 77955370669 scopus 로고    scopus 로고
    • Effects of HIF-1alpha and HIF2alpha on growth and metabolism of clear-cell renal cell carcinoma 786-0 xenografts
    • S. Biswas, H. Troy, and R. Leek et al. Effects of HIF-1alpha and HIF2alpha on growth and metabolism of clear-cell renal cell carcinoma 786-0 xenografts J Oncol 2010 2010 757908
    • (2010) J Oncol , vol.2010 , pp. 757908
    • Biswas, S.1    Troy, H.2    Leek, R.3
  • 6
    • 39749132878 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein: An update
    • W.G. Kaelin Jr. The von Hippel-Lindau tumor suppressor protein: an update Methods Enzymol 435 2007 371 383
    • (2007) Methods Enzymol , vol.435 , pp. 371-383
    • Kaelin, Jr.W.G.1
  • 7
    • 84903841946 scopus 로고    scopus 로고
    • The evolving landscape of metastatic renal cell carcinoma
    • D.Y. Heng, and T.K. Choueiri The evolving landscape of metastatic renal cell carcinoma Am Soc Clin Oncol Educ Book 2012 299 302
    • (2012) Am Soc Clin Oncol Educ Book , pp. 299-302
    • Heng, D.Y.1    Choueiri, T.K.2
  • 8
    • 84882781441 scopus 로고    scopus 로고
    • Pazopanib versus sunitinib in metastatic renal-cell carcinoma
    • R.J. Motzer, T.E. Hutson, and D. Cella et al. Pazopanib versus sunitinib in metastatic renal-cell carcinoma N Engl J Med 369 2013 722 731
    • (2013) N Engl J Med , vol.369 , pp. 722-731
    • Motzer, R.J.1    Hutson, T.E.2    Cella, D.3
  • 9
    • 84865506371 scopus 로고    scopus 로고
    • Patient preference between pazopanib (Paz) and sunitinib (Sun): Results of a randomized double-blind, placebo-controlled, cross-over study in patients with metastatic renal cell carcinoma (mRCC) - PISCES study, NCT 01064310
    • (abstract CRA4502)
    • B.J. Escudier, C. Porta, and P. Bono et al. Patient preference between pazopanib (Paz) and sunitinib (Sun): results of a randomized double-blind, placebo-controlled, cross-over study in patients with metastatic renal cell carcinoma (mRCC) - PISCES study, NCT 01064310 J Clin Oncol 30 2012 (abstract CRA4502)
    • (2012) J Clin Oncol , vol.30
    • Escudier, B.J.1    Porta, C.2    Bono, P.3
  • 10
    • 79959796486 scopus 로고    scopus 로고
    • NICE guidance on pazopanib for first-line treatment of advanced renal-cell carcinoma
    • C. Griffiths, N. Hay, F. Sutcliffe, and A. Stevens NICE guidance on pazopanib for first-line treatment of advanced renal-cell carcinoma Lancet Oncol 12 2011 221 222
    • (2011) Lancet Oncol , vol.12 , pp. 221-222
    • Griffiths, C.1    Hay, N.2    Sutcliffe, F.3    Stevens, A.4
  • 11
    • 67651214070 scopus 로고    scopus 로고
    • NCCN clinical practice guidelines in oncology: Kidney cancer
    • R.J. Motzer, N. Agarwal, and C. Beard et al. NCCN clinical practice guidelines in oncology: kidney cancer J Natl Compr Canc Netw 7 2009 618 630
    • (2009) J Natl Compr Canc Netw , vol.7 , pp. 618-630
    • Motzer, R.J.1    Agarwal, N.2    Beard, C.3
  • 12
    • 83955162846 scopus 로고    scopus 로고
    • Sequencing of agents for metastatic renal cell carcinoma: Can we customize therapy?
    • G. Sonpavde, T.K. Choueiri, and B. Escudier et al. Sequencing of agents for metastatic renal cell carcinoma: can we customize therapy? Eur Urol 61 2012 307 316
    • (2012) Eur Urol , vol.61 , pp. 307-316
    • Sonpavde, G.1    Choueiri, T.K.2    Escudier, B.3
  • 13
    • 84884583240 scopus 로고    scopus 로고
    • The role of aberrant VHL/HIF pathway elements in predicting clinical outcome to pazopanib therapy in patients with metastatic clear-cell renal cell carcinoma
    • T.K. Choueiri, A. Fay, and R. Gagnon et al. The role of aberrant VHL/HIF pathway elements in predicting clinical outcome to pazopanib therapy in patients with metastatic clear-cell renal cell carcinoma Clin Cancer Res 19 2013 5218 5226
    • (2013) Clin Cancer Res , vol.19 , pp. 5218-5226
    • Choueiri, T.K.1    Fay, A.2    Gagnon, R.3
  • 14
    • 84883179205 scopus 로고    scopus 로고
    • Combination therapy in metastatic renal cell cancer
    • A. Ravaud, M. Gross-Goupil, and J. Bellmunt Combination therapy in metastatic renal cell cancer Semin Oncol 40 2013 472 481
    • (2013) Semin Oncol , vol.40 , pp. 472-481
    • Ravaud, A.1    Gross-Goupil, M.2    Bellmunt, J.3
  • 15
    • 77955470097 scopus 로고    scopus 로고
    • Clinical outcome in metastatic renal cell carcinoma patients after failure of initial vascular endothelial growth factor-targeted therapy
    • M.M. Vickers, T.K. Choueiri, and M. Rogers et al. Clinical outcome in metastatic renal cell carcinoma patients after failure of initial vascular endothelial growth factor-targeted therapy Urology 76 2010 430 434
    • (2010) Urology , vol.76 , pp. 430-434
    • Vickers, M.M.1    Choueiri, T.K.2    Rogers, M.3
  • 16
    • 48649107474 scopus 로고    scopus 로고
    • Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
    • R.J. Motzer, B. Escudier, and S. Oudard et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial Lancet 372 2008 449 456
    • (2008) Lancet , vol.372 , pp. 449-456
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3
  • 17
    • 82755183572 scopus 로고    scopus 로고
    • Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
    • B.I. Rini, B. Escudier, and P. Tomczak et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial Lancet 378 2011 1931 1939
    • (2011) Lancet , vol.378 , pp. 1931-1939
    • Rini, B.I.1    Escudier, B.2    Tomczak, P.3
  • 19
    • 79959782949 scopus 로고    scopus 로고
    • Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): An Italian multicentre retrospective analysis of 189 patient cases
    • C. Porta, G. Procopio, and G. Carteni et al. Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): an Italian multicentre retrospective analysis of 189 patient cases BJU Int 108 2011 E250 E257
    • (2011) BJU Int , vol.108
    • Porta, C.1    Procopio, G.2    Carteni, G.3
  • 20
    • 67349163859 scopus 로고    scopus 로고
    • Sequential sorafenib and sunitinib for renal cell carcinoma
    • M.P. Sablin, S. Negrier, and A. Ravaud et al. Sequential sorafenib and sunitinib for renal cell carcinoma J Urol 182 2009 29 34
    • (2009) J Urol , vol.182 , pp. 29-34
    • Sablin, M.P.1    Negrier, S.2    Ravaud, A.3
  • 21
    • 58949092548 scopus 로고    scopus 로고
    • Sequential therapy with sorafenib and sunitinib in renal cell carcinoma
    • A.Z. Dudek, J. Zolnierek, A. Dham, B.R. Lindgren, and C. Szczylik Sequential therapy with sorafenib and sunitinib in renal cell carcinoma Cancer 115 2009 61 67
    • (2009) Cancer , vol.115 , pp. 61-67
    • Dudek, A.Z.1    Zolnierek, J.2    Dham, A.3    Lindgren, B.R.4    Szczylik, C.5
  • 22
    • 55649103188 scopus 로고    scopus 로고
    • Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: A retrospective outcome analysis
    • C. Eichelberg, R. Heuer, and F.K. Chun et al. Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: a retrospective outcome analysis Eur Urol 54 2008 1373 1378
    • (2008) Eur Urol , vol.54 , pp. 1373-1378
    • Eichelberg, C.1    Heuer, R.2    Chun, F.K.3
  • 23
    • 65549155468 scopus 로고    scopus 로고
    • A multicenter prospective trial of sorafenib in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) refractory to prior sunitinib or bevacizumab
    • (abstract 5123)
    • D.R. Shepard, B.I. Rini, and J.A. Garcia et al. A multicenter prospective trial of sorafenib in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) refractory to prior sunitinib or bevacizumab J Clin Oncol 26 2008 (abstract 5123)
    • (2008) J Clin Oncol , vol.26
    • Shepard, D.R.1    Rini, B.I.2    Garcia, J.A.3
  • 24
    • 73749087933 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with sunitinib-refractory metastatic renal cell cancer
    • G. Di Lorenzo, G. Carteni, and R. Autorino et al. Phase II study of sorafenib in patients with sunitinib-refractory metastatic renal cell cancer J Clin Oncol 27 2009 4469 4474
    • (2009) J Clin Oncol , vol.27 , pp. 4469-4474
    • Di Lorenzo, G.1    Carteni, G.2    Autorino, R.3
  • 25
    • 84899077396 scopus 로고    scopus 로고
    • Sequencing systemic therapies in advanced RCC
    • T. Powles, and S.M. Crusz Sequencing systemic therapies in advanced RCC J Clin Oncol 2013 2013 172 174
    • (2013) J Clin Oncol , vol.2013 , pp. 172-174
    • Powles, T.1    Crusz, S.M.2
  • 27
    • 84879526008 scopus 로고    scopus 로고
    • Record-3: Phase II randomized trial comparing sequential first-line everolimus (EVE) and second-line sunitinib (SUN) versus first-line SUN and second-line EVE in patients with metastatic renal cell carcinoma (mRCC)
    • (abstract 4504)
    • R.J. Motzer, C.H. Barrios, and T.M. Kim et al. Record-3: phase II randomized trial comparing sequential first-line everolimus (EVE) and second-line sunitinib (SUN) versus first-line SUN and second-line EVE in patients with metastatic renal cell carcinoma (mRCC) J Clin Oncol 31 2013 (abstract 4504)
    • (2013) J Clin Oncol , vol.31
    • Motzer, R.J.1    Barrios, C.H.2    Kim, T.M.3
  • 28
    • 65949110334 scopus 로고    scopus 로고
    • Novel therapeutics for metastatic renal cell carcinoma
    • T.E. Hutson, and R.A. Figlin Novel therapeutics for metastatic renal cell carcinoma Cancer 115 suppl 10 2009 2361 2367
    • (2009) Cancer , vol.115 , Issue.SUPPL. 10 , pp. 2361-2367
    • Hutson, T.E.1    Figlin, R.A.2
  • 30
    • 35648938219 scopus 로고    scopus 로고
    • Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer
    • R.M. Bukowski, F.F. Kabbinavar, and R.A. Figlin et al. Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer J Clin Oncol 25 2007 4536 4541
    • (2007) J Clin Oncol , vol.25 , pp. 4536-4541
    • Bukowski, R.M.1    Kabbinavar, F.F.2    Figlin, R.A.3
  • 31
    • 84861735450 scopus 로고    scopus 로고
    • Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: Clinical characteristics, risk factors, and subsequent therapy
    • D.Y. Heng, M.J. Mackenzie, and U.N. Vaishampayan et al. Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy Ann Oncol 23 2012 1549 1555
    • (2012) Ann Oncol , vol.23 , pp. 1549-1555
    • Heng, D.Y.1    Mackenzie, M.J.2    Vaishampayan, U.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.